Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA   Type   Machinery gene
Locus tag   IF749_RS02475 Genome accession   NZ_CP062334
Coordinates   436330..437016 (+) Length   228 a.a.
NCBI ID   WP_001793467.1    Uniprot ID   A0A641AAY3
Organism   Staphylococcus aureus strain NAS_NP_164     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 431330..442016
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IF749_RS02440 (IF749_02440) yqeH 431857..432957 (+) 1101 WP_001280141.1 ribosome biogenesis GTPase YqeH -
  IF749_RS02445 (IF749_02445) aroE 432971..433777 (+) 807 WP_000666748.1 shikimate dehydrogenase -
  IF749_RS02450 (IF749_02450) yhbY 433781..434071 (+) 291 WP_000955235.1 ribosome assembly RNA-binding protein YhbY -
  IF749_RS02455 (IF749_02455) nadD 434074..434643 (+) 570 WP_000725167.1 nicotinate (nicotinamide) nucleotide adenylyltransferase -
  IF749_RS02460 (IF749_02460) yqeK 434633..435217 (+) 585 WP_001019324.1 bis(5'-nucleosyl)-tetraphosphatase (symmetrical) YqeK -
  IF749_RS02465 (IF749_02465) rsfS 435218..435571 (+) 354 WP_001088022.1 ribosome silencing factor -
  IF749_RS02470 (IF749_02470) - 435574..436290 (+) 717 WP_000084829.1 class I SAM-dependent methyltransferase -
  IF749_RS02475 (IF749_02475) comEA 436330..437016 (+) 687 WP_001793467.1 ComEA family DNA-binding protein Machinery gene
  IF749_RS02480 (IF749_02480) - 437108..437569 (+) 462 WP_000439693.1 ComE operon protein 2 -
  IF749_RS02485 (IF749_02485) comEC 437574..439775 (+) 2202 WP_064130030.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  IF749_RS02490 (IF749_02490) holA 439832..440806 (+) 975 WP_001282568.1 DNA polymerase III subunit delta -
  IF749_RS02495 (IF749_02495) rpsT 440851..441102 (-) 252 WP_001274017.1 30S ribosomal protein S20 -

Sequence

Protein


Download         Length: 228 a.a.        Molecular weight: 25786.50 Da        Isoelectric Point: 9.6753

>NTDB_id=487898 IF749_RS02475 WP_001793467.1 436330..437016(+) (comEA) [Staphylococcus aureus strain NAS_NP_164]
MVLLYQFLLRYKDFLTQWKLYIISAVVLIMVLIGFIFWRQDDYTSRNFENKDNALKQSTSENSSLSKVEDVQVKDGDNSK
NKGPVYVDVKGAVKHPNVYKMTSKDRVVDLLDKAQLLEDADVSQINLSEKLTDQKMIFIPHKGQKNVEPQIGVNSVHVKN
GNTNNTKVNLNTASVSELMSVPGVGQAKANAIVEYRNQQGAFQEIDDLKKVKGFGSKTFDKLKSYFTI

Nucleotide


Download         Length: 687 bp        

>NTDB_id=487898 IF749_RS02475 WP_001793467.1 436330..437016(+) (comEA) [Staphylococcus aureus strain NAS_NP_164]
GTGGTTTTATTGTATCAATTTTTATTACGCTATAAAGATTTTTTAACTCAATGGAAGTTATATATTATAAGTGCTGTTGT
TTTAATTATGGTATTAATTGGTTTTATATTCTGGAGACAAGATGATTATACTTCAAGAAATTTTGAAAATAAAGATAATG
CTCTGAAACAAAGCACTAGTGAAAATAGTAGTTTGTCCAAAGTAGAAGATGTCCAGGTCAAAGATGGAGATAATTCCAAA
AATAAGGGTCCTGTATATGTCGATGTAAAAGGTGCTGTTAAACATCCTAATGTTTATAAAATGACATCTAAGGATAGAGT
AGTTGATTTACTTGATAAAGCACAATTATTGGAGGATGCAGATGTAAGTCAAATTAATTTGTCTGAAAAATTAACAGATC
AAAAAATGATTTTCATACCTCATAAAGGACAAAAGAATGTTGAACCACAAATTGGAGTAAACAGTGTGCATGTAAAAAAT
GGGAACACAAATAATACTAAAGTAAATTTAAATACCGCATCTGTATCAGAATTGATGTCTGTTCCTGGAGTAGGGCAAGC
TAAAGCTAATGCAATTGTTGAATATCGCAACCAACAAGGTGCATTTCAAGAAATTGACGATTTGAAAAAAGTAAAAGGTT
TTGGAAGTAAAACTTTTGATAAACTGAAATCTTATTTCACGATATAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(164-227)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A641AAY3

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA Staphylococcus aureus MW2

100

100

1
  comEA Staphylococcus aureus N315

97.368

100

0.974