Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   J6O57_RS09775 Genome accession   NZ_CP073718
Coordinates   1990073..1990729 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain CX08     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1985073..1995729
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J6O57_RS09745 (J6O57_09660) dcyD 1985953..1986939 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  J6O57_RS09750 (J6O57_09665) tcyL 1986954..1987622 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  J6O57_RS09755 (J6O57_09670) tcyN 1987619..1988371 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  J6O57_RS09760 (J6O57_09675) sdiA 1988601..1989323 (+) 723 WP_001154276.1 transcriptional regulator SdiA -
  J6O57_RS09765 (J6O57_09680) yecF 1989390..1989614 (-) 225 WP_223566729.1 DUF2594 family protein YecF -
  J6O57_RS09770 (J6O57_09685) yecU 1989601..1989777 (-) 177 WP_000590347.1 protein YecU -
  J6O57_RS24320 - 1989860..1989931 (-) 72 Protein_1914 transcriptional regulator -
  J6O57_RS09775 (J6O57_09690) letA 1990073..1990729 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  J6O57_RS09780 (J6O57_09695) uvrC 1990726..1992558 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  J6O57_RS09785 (J6O57_09700) pgsA 1992615..1993163 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  J6O57_RS09805 (J6O57_09720) yecA 1993813..1994478 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=487788 J6O57_RS09775 WP_000611335.1 1990073..1990729(+) (letA) [Escherichia coli strain CX08]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=487788 J6O57_RS09775 WP_000611335.1 1990073..1990729(+) (letA) [Escherichia coli strain CX08]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486