Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   KD735_RS10115 Genome accession   NZ_CP073624
Coordinates   2058364..2059020 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain AW1.7     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2053364..2064020
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KD735_RS10085 (KD735_09995) dcyD 2054244..2055230 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  KD735_RS10090 (KD735_10000) tcyL 2055245..2055913 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  KD735_RS10095 (KD735_10005) tcyN 2055910..2056662 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  KD735_RS10100 (KD735_10010) sdiA 2056892..2057614 (+) 723 Protein_1974 transcriptional regulator SdiA -
  KD735_RS10105 (KD735_10015) yecF 2057681..2057905 (-) 225 WP_054626268.1 DUF2594 family protein YecF -
  KD735_RS10110 (KD735_10020) yecU 2057892..2058068 (-) 177 WP_000590347.1 protein YecU -
  KD735_RS10115 (KD735_10025) letA 2058364..2059020 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  KD735_RS10120 (KD735_10030) uvrC 2059017..2060849 (+) 1833 WP_054626269.1 excinuclease ABC subunit UvrC Machinery gene
  KD735_RS10125 (KD735_10035) pgsA 2060906..2061454 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  KD735_RS10145 (KD735_10055) yecA 2062104..2062769 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=487512 KD735_RS10115 WP_000611335.1 2058364..2059020(+) (letA) [Escherichia coli strain AW1.7]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=487512 KD735_RS10115 WP_000611335.1 2058364..2059020(+) (letA) [Escherichia coli strain AW1.7]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486