Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   TL13_RS02285 Genome accession   NC_021213
Coordinates   454601..455242 (+) Length   213 a.a.
NCBI ID   WP_015646507.1    Uniprot ID   -
Organism   Streptococcus suis TL13     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 449601..460242
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  TL13_RS02265 (TL13_0450) - 449901..450638 (+) 738 WP_004194145.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  TL13_RS02270 (TL13_0451) pknB 450638..452296 (+) 1659 Protein_406 Stk1 family PASTA domain-containing Ser/Thr kinase -
  TL13_RS11055 - 452417..452632 (+) 216 Protein_407 serine/threonine protein kinase -
  TL13_RS02275 (TL13_0452) liaF 452921..453616 (+) 696 WP_015646506.1 cell wall-active antibiotics response protein LiaF -
  TL13_RS02280 (TL13_0453) - 453613..454629 (+) 1017 WP_002937028.1 sensor histidine kinase -
  TL13_RS02285 (TL13_0454) vraR 454601..455242 (+) 642 WP_015646507.1 response regulator transcription factor Regulator
  TL13_RS02290 (TL13_0455) - 455292..456692 (+) 1401 WP_015646508.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  TL13_RS02295 (TL13_0456) - 456694..457065 (+) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -
  TL13_RS02300 (TL13_0457) cysK 457091..458017 (-) 927 WP_015646509.1 cysteine synthase A -
  TL13_RS02305 (TL13_0458) - 458107..458739 (-) 633 WP_015646510.1 YigZ family protein -
  TL13_RS02310 (TL13_0459) comFA/cflA 458796..460088 (+) 1293 WP_015646511.1 DEAD/DEAH box helicase Machinery gene

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23818.41 Da        Isoelectric Point: 4.8970

>NTDB_id=48621 TL13_RS02285 WP_015646507.1 454601..455242(+) (vraR) [Streptococcus suis TL13]
MNTIRVMLVDDHEMVRLGLKSYLNLQPDVEVVAEASDGEEGLAKALEVKPDVVVMDLVMPKMTGVEATLALLKEWPQAQI
VILTSYLDNEKIYPVLEAGARGYMLKTSSADEILVAIRKVALGEYAIETEVEKKVEHHKRHPDLHDDLTAREREILTLLA
KGYDNQRIADESFISLKTVKTHVSNILSKLAVSDRTQAVVYAFQHGLVAQEDQ

Nucleotide


Download         Length: 642 bp        

>NTDB_id=48621 TL13_RS02285 WP_015646507.1 454601..455242(+) (vraR) [Streptococcus suis TL13]
ATGAATACGATTCGAGTGATGCTGGTTGACGACCATGAGATGGTTCGCCTAGGATTGAAAAGTTACTTAAATTTACAGCC
AGATGTTGAAGTAGTTGCAGAAGCTAGTGATGGCGAGGAAGGTTTGGCTAAAGCGTTAGAGGTTAAACCTGATGTTGTAG
TGATGGACTTGGTTATGCCCAAGATGACTGGCGTAGAAGCAACTCTGGCCTTGCTGAAGGAATGGCCGCAAGCGCAGATT
GTCATCCTGACCTCCTATCTAGATAATGAGAAAATCTATCCTGTGCTGGAAGCAGGAGCTCGTGGTTATATGTTGAAAAC
GTCAAGTGCTGACGAAATCTTAGTAGCCATCCGCAAGGTAGCTCTTGGAGAATATGCTATTGAGACAGAAGTAGAGAAAA
AAGTAGAGCACCATAAACGCCACCCAGATTTACATGATGACTTGACAGCTCGCGAACGCGAAATCTTGACGTTGTTAGCC
AAGGGATATGATAATCAACGAATTGCAGATGAGTCCTTCATTTCCCTAAAAACTGTTAAGACCCATGTTTCCAATATCTT
ATCCAAACTAGCTGTTAGCGATCGTACTCAAGCAGTTGTTTATGCTTTCCAGCATGGTTTGGTGGCGCAAGAGGATCAAT
AG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-117)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.589

97.183

0.531
  degU Bacillus subtilis subsp. subtilis str. 168

38.938

100

0.413

Multiple sequence alignment