Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   KBW97_RS08970 Genome accession   NZ_CP072986
Coordinates   1888880..1889536 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain T159A     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1883880..1894536
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KBW97_RS08940 dcyD 1884759..1885745 (+) 987 WP_001128215.1 D-cysteine desulfhydrase -
  KBW97_RS08945 tcyL 1885760..1886428 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  KBW97_RS08950 tcyN 1886425..1887177 (+) 753 WP_001272991.1 L-cystine ABC transporter ATP-binding protein TcyN -
  KBW97_RS08955 sdiA 1887407..1888129 (+) 723 WP_001152715.1 transcriptional regulator SdiA -
  KBW97_RS08960 yecF 1888197..1888421 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  KBW97_RS08965 yecU 1888408..1888584 (-) 177 WP_000590347.1 protein YecU -
  KBW97_RS23570 - 1888667..1888738 (-) 72 Protein_1768 transcriptional regulator -
  KBW97_RS08970 letA 1888880..1889536 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  KBW97_RS08975 uvrC 1889533..1891365 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  KBW97_RS08980 pgsA 1891422..1891970 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  KBW97_RS09000 yecA 1892620..1893285 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=486106 KBW97_RS08970 WP_000611335.1 1888880..1889536(+) (letA) [Escherichia coli strain T159A]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=486106 KBW97_RS08970 WP_000611335.1 1888880..1889536(+) (letA) [Escherichia coli strain T159A]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486