Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   KBW65_RS19500 Genome accession   NZ_CP072976
Coordinates   4068991..4069647 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain EC2341     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 4063991..4074647
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  KBW65_RS19470 (KBW65_19470) dcyD 4064870..4065856 (+) 987 WP_001128218.1 D-cysteine desulfhydrase -
  KBW65_RS19475 (KBW65_19475) tcyL 4065871..4066539 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  KBW65_RS19480 (KBW65_19480) tcyN 4066536..4067288 (+) 753 WP_001273008.1 L-cystine ABC transporter ATP-binding protein TcyN -
  KBW65_RS19485 (KBW65_19485) sdiA 4067518..4068240 (+) 723 WP_001154273.1 transcriptional regulator SdiA -
  KBW65_RS19490 (KBW65_19490) yecF 4068308..4068532 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  KBW65_RS19495 (KBW65_19495) yecU 4068519..4068695 (-) 177 WP_000590347.1 protein YecU -
  KBW65_RS25310 - 4068778..4068849 (-) 72 Protein_3843 transcriptional regulator -
  KBW65_RS19500 (KBW65_19500) letA 4068991..4069647 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  KBW65_RS19505 (KBW65_19505) uvrC 4069644..4071476 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  KBW65_RS19510 (KBW65_19510) pgsA 4071533..4072081 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  KBW65_RS19530 (KBW65_19530) yecA 4072731..4073396 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=485979 KBW65_RS19500 WP_000611335.1 4068991..4069647(+) (letA) [Escherichia coli strain EC2341]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=485979 KBW65_RS19500 WP_000611335.1 4068991..4069647(+) (letA) [Escherichia coli strain EC2341]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486