Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   I872_RS06095 Genome accession   NC_021175
Coordinates   1219093..1219725 (-) Length   210 a.a.
NCBI ID   WP_015605263.1    Uniprot ID   A0ABM5NKM9
Organism   Streptococcus cristatus AS 1.3089     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1214093..1224725
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  I872_RS06070 (I872_06055) comFA/cflA 1214203..1215504 (-) 1302 WP_041826810.1 DEAD/DEAH box helicase Machinery gene
  I872_RS06075 (I872_06060) - 1215561..1216196 (+) 636 WP_015605259.1 YigZ family protein -
  I872_RS06080 (I872_06065) cysK 1216313..1217242 (+) 930 WP_015605260.1 cysteine synthase A -
  I872_RS06085 (I872_06070) - 1217293..1217655 (-) 363 WP_015605261.1 S1 RNA-binding domain-containing protein -
  I872_RS06090 (I872_06075) - 1217655..1219055 (-) 1401 WP_015605262.1 bifunctional Cof-type HAD-IIB family hydrolase/peptidylprolyl isomerase -
  I872_RS06095 (I872_06080) vraR 1219093..1219725 (-) 633 WP_015605263.1 response regulator transcription factor Regulator
  I872_RS06100 (I872_06085) - 1219703..1220722 (-) 1020 WP_015605264.1 sensor histidine kinase -
  I872_RS06105 (I872_06090) liaF 1220719..1221414 (-) 696 WP_015605265.1 cell wall-active antibiotics response protein LiaF -
  I872_RS06110 (I872_06095) - 1221637..1222452 (-) 816 WP_015605266.1 endonuclease/exonuclease/phosphatase family protein -
  I872_RS06115 (I872_06100) - 1222470..1224659 (-) 2190 WP_041826811.1 PTS transporter subunit IIBC -

Sequence

Protein


Download         Length: 210 a.a.        Molecular weight: 23939.42 Da        Isoelectric Point: 4.7441

>NTDB_id=48533 I872_RS06095 WP_015605263.1 1219093..1219725(-) (vraR) [Streptococcus cristatus AS 1.3089]
MRILLVDDHQMVRLGLKSFFELQDDIEEVTEATNGREGVEKALESRPDVIMMDIVMPEMSGIDATLAILKEWPEAKILIL
TSYLDNEKIYPVLDAGAHGYMLKTSSADEILHAVRKVAKGEFAIETEVSKKVEYHRNHIELYEDLTARERDILGLLAKGY
ENQRIADELFISLKTVKTHVSNILSKLEVSDRTQAVVYAFQHHLVPQDDF

Nucleotide


Download         Length: 633 bp        

>NTDB_id=48533 I872_RS06095 WP_015605263.1 1219093..1219725(-) (vraR) [Streptococcus cristatus AS 1.3089]
ATGAGAATATTACTAGTGGATGACCATCAAATGGTCAGATTGGGCTTGAAAAGCTTTTTTGAATTACAGGACGATATTGA
AGAAGTAACAGAGGCTACAAATGGTAGAGAAGGTGTCGAAAAGGCTTTGGAAAGCCGTCCAGATGTGATTATGATGGATA
TCGTCATGCCAGAGATGAGTGGCATTGATGCCACCTTGGCTATCTTGAAAGAATGGCCAGAGGCAAAGATTTTAATCTTG
ACTTCCTATCTGGACAATGAAAAAATCTATCCTGTGTTGGATGCGGGTGCTCATGGCTATATGTTGAAGACTTCTAGCGC
GGATGAAATTCTCCACGCCGTCAGAAAGGTTGCAAAAGGTGAATTTGCCATTGAAACAGAAGTCAGCAAGAAGGTTGAAT
ACCATCGAAATCATATAGAGCTTTATGAGGATTTGACAGCGCGGGAGCGGGATATTTTGGGGCTTCTAGCCAAGGGATAT
GAAAACCAGCGGATCGCTGATGAGCTCTTTATTTCCTTAAAAACGGTCAAGACGCATGTGTCCAATATTTTGTCTAAGCT
GGAAGTGAGCGATCGAACCCAAGCAGTCGTCTACGCTTTTCAGCATCACCTTGTTCCGCAAGACGATTTTTAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(145-199)

Response regulator receiver domain (Response_reg)

(3-114)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

52.913

98.095

0.519
  degU Bacillus subtilis subsp. subtilis str. 168

37.946

100

0.405

Multiple sequence alignment