Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilR   Type   Regulator
Locus tag   IF130_RS05685 Genome accession   NZ_CP061840
Coordinates   1254288..1255616 (+) Length   442 a.a.
NCBI ID   WP_011213530.1    Uniprot ID   Q5WXB6
Organism   Legionella pneumophila subsp. pneumophila strain AW-13-4     
Function   regulate pilin expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 1249288..1260616
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IF130_RS05665 (IF130_05665) amrS 1249418..1250494 (+) 1077 WP_011213526.1 AmmeMemoRadiSam system radical SAM enzyme -
  IF130_RS05670 (IF130_05670) - 1250553..1250972 (+) 420 WP_011213527.1 lpg1171 family Dot/Icm T4SS effector -
  IF130_RS05675 (IF130_05675) lidL 1251122..1252606 (+) 1485 WP_072363922.1 Dot/Icm type IV secretion system effector LidL -
  IF130_RS05680 (IF130_05680) - 1252705..1254291 (+) 1587 WP_011213529.1 PAS domain-containing sensor histidine kinase -
  IF130_RS05685 (IF130_05685) pilR 1254288..1255616 (+) 1329 WP_011213530.1 sigma-54 dependent transcriptional regulator Regulator
  IF130_RS05690 (IF130_05690) - 1256046..1256291 (+) 246 WP_011213531.1 hypothetical protein -
  IF130_RS05695 (IF130_05695) - 1256729..1257664 (-) 936 WP_011213532.1 alpha/beta fold hydrolase -
  IF130_RS05700 (IF130_05700) - 1257943..1259379 (-) 1437 WP_011213533.1 M48 family metalloprotease -
  IF130_RS05705 (IF130_05705) ribD 1259442..1260515 (+) 1074 WP_011213534.1 bifunctional diaminohydroxyphosphoribosylaminopyrimidine deaminase/5-amino-6-(5-phosphoribosylamino)uracil reductase RibD -

Sequence

Protein


Download         Length: 442 a.a.        Molecular weight: 49298.31 Da        Isoelectric Point: 6.9042

>NTDB_id=484967 IF130_RS05685 WP_011213530.1 1254288..1255616(+) (pilR) [Legionella pneumophila subsp. pneumophila strain AW-13-4]
MTKSKVLVIDDEPDIRELLTLTLSRMGLTCDAVSDFKQGIEHIKQNYYSLVLTDMRLPDGDGIEIVKFIQKYKPQMPVAV
ITAYGNVEGAVNTLKAGAFDYVSKPIDLKMLRDLVKTALSMQNPPTEKPDEDLLVGESLVMQQLRENIHKLARSQAPVFI
QGASGVGKELVAQLIHVNGPRKDKPFIPVNCGAIPGELMESEFFGHKKGSFTGAISDKTGLFVAAHGGTLFLDEIAELPL
AMQVKLLRAIQEKAIKPIGELYEVPVDVRILSASHKNLIEEVNAGAFRQDLYYRINVIELRVPTLMERLSDIPCLTEAIL
RKLSKNQNRNLVKINPSCFEILSRYHFPGNVRELENILERAMAMCEGEVIEPSDLHLPRTTITPAVAVPSTSTNLNGYLQ
DQEKELILDALEKTKWNRTAAAQLLGVSFRTLRYRLKKLGLD

Nucleotide


Download         Length: 1329 bp        

>NTDB_id=484967 IF130_RS05685 WP_011213530.1 1254288..1255616(+) (pilR) [Legionella pneumophila subsp. pneumophila strain AW-13-4]
ATGACCAAAAGTAAAGTGCTTGTTATAGATGACGAACCAGATATAAGAGAGTTATTAACTCTTACTTTATCACGTATGGG
TTTAACTTGCGATGCAGTGTCTGACTTTAAGCAAGGCATAGAACATATAAAACAAAATTATTATTCTTTGGTTTTAACCG
ATATGCGTTTACCTGATGGAGATGGTATAGAAATTGTTAAATTCATTCAGAAATACAAACCGCAGATGCCAGTTGCCGTC
ATTACTGCCTATGGAAATGTCGAGGGTGCGGTCAACACTTTAAAGGCGGGTGCATTTGATTACGTATCAAAACCTATAGA
CTTAAAAATGCTTAGAGATCTCGTTAAGACGGCATTATCCATGCAAAACCCGCCTACCGAGAAGCCTGATGAAGATCTAC
TGGTTGGTGAAAGTTTGGTAATGCAACAACTTCGTGAAAACATTCATAAATTAGCTCGCAGTCAGGCACCAGTTTTTATT
CAAGGAGCTTCAGGTGTTGGGAAAGAATTGGTCGCTCAGTTGATCCATGTTAATGGTCCCAGAAAGGATAAGCCATTTAT
TCCTGTAAACTGTGGCGCAATACCTGGTGAGTTGATGGAATCAGAGTTTTTTGGCCATAAAAAAGGGAGCTTTACAGGAG
CGATTTCTGATAAAACAGGGTTGTTTGTTGCGGCTCATGGTGGCACTTTGTTTCTTGATGAAATCGCCGAACTTCCTCTC
GCCATGCAGGTAAAATTGCTACGTGCCATTCAGGAGAAGGCAATTAAGCCGATAGGTGAGTTATATGAAGTTCCTGTGGA
TGTTCGCATCCTAAGTGCGAGTCATAAAAATTTGATTGAGGAAGTTAATGCAGGGGCATTTCGTCAAGATTTGTATTATC
GAATTAATGTGATTGAATTGCGTGTCCCAACTTTAATGGAAAGGCTTTCAGATATTCCTTGCCTGACAGAGGCGATATTA
AGAAAATTATCTAAAAATCAAAACAGAAACCTGGTGAAAATAAATCCATCCTGTTTTGAAATATTGAGTCGTTATCATTT
TCCAGGAAATGTCAGAGAACTGGAGAATATCCTCGAGCGTGCCATGGCTATGTGTGAAGGAGAGGTTATAGAACCATCCG
ATTTGCATTTGCCCAGAACAACAATAACCCCAGCTGTTGCCGTACCCTCCACATCAACTAACTTAAATGGTTACCTTCAG
GATCAGGAAAAAGAGTTAATTCTTGATGCGCTCGAGAAAACAAAATGGAACAGAACCGCTGCTGCCCAACTACTGGGGGT
CAGCTTCCGAACTCTCCGTTATCGATTAAAAAAACTGGGCCTTGATTAG

Domains

Predicted by InterproScan.

Bacterial regulatory protein, Fis family (HTH_8)

(399-439)

Response regulator receiver domain (Response_reg)

(6-115)

Sigma-54 interaction domain (Sigma54_activat)

(134-300)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q5WXB6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilR Pseudomonas aeruginosa PAK

59.417

100

0.6
  pilR Acinetobacter baumannii strain A118

48.584

100

0.505