Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   J8I94_RS10395 Genome accession   NZ_CP072686
Coordinates   2188292..2188948 (+) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain FP4     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2183292..2193948
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J8I94_RS10365 (J8I94_10265) dcyD 2184172..2185157 (+) 986 Protein_2035 D-cysteine desulfhydrase -
  J8I94_RS10370 (J8I94_10270) tcyL 2185172..2185840 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  J8I94_RS10375 (J8I94_10275) tcyN 2185837..2186589 (+) 753 WP_001272998.1 L-cystine ABC transporter ATP-binding protein TcyN -
  J8I94_RS10380 (J8I94_10280) sdiA 2186819..2187541 (+) 723 WP_001154255.1 transcriptional regulator SdiA -
  J8I94_RS10385 (J8I94_10285) yecF 2187609..2187833 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  J8I94_RS10390 (J8I94_10290) yecU 2187820..2187996 (-) 177 WP_001307856.1 protein YecU -
  J8I94_RS10395 (J8I94_10295) letA 2188292..2188948 (+) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  J8I94_RS10400 (J8I94_10300) uvrC 2188945..2190777 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  J8I94_RS10405 (J8I94_10305) pgsA 2190834..2191382 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  J8I94_RS10425 (J8I94_10325) yecA 2192031..2192696 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=484499 J8I94_RS10395 WP_000611328.1 2188292..2188948(+) (letA) [Escherichia coli strain FP4]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=484499 J8I94_RS10395 WP_000611328.1 2188292..2188948(+) (letA) [Escherichia coli strain FP4]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAATGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGAGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGATATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482