Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   J8F87_RS09485 Genome accession   NZ_CP072564
Coordinates   1980347..1981003 (+) Length   218 a.a.
NCBI ID   WP_081508827.1    Uniprot ID   -
Organism   Escherichia coli strain WG5::PA2     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1975347..1986003
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J8F87_RS09455 (J8F87_09390) dcyD 1976227..1977213 (+) 987 WP_001128242.1 D-cysteine desulfhydrase -
  J8F87_RS09460 (J8F87_09395) tcyL 1977228..1977896 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  J8F87_RS09465 (J8F87_09400) tcyN 1977893..1978645 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  J8F87_RS09470 (J8F87_09405) sdiA 1978875..1979597 (+) 723 WP_081508826.1 transcriptional regulator SdiA -
  J8F87_RS09475 (J8F87_09410) yecF 1979664..1979888 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  J8F87_RS09480 (J8F87_09415) yecU 1979875..1980051 (-) 177 WP_000590347.1 protein YecU -
  J8F87_RS22535 - 1980134..1980205 (-) 72 Protein_1855 transcriptional regulator -
  J8F87_RS09485 (J8F87_09420) letA 1980347..1981003 (+) 657 WP_081508827.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  J8F87_RS09490 (J8F87_09425) uvrC 1981000..1982832 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  J8F87_RS09495 (J8F87_09430) pgsA 1982889..1983437 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  J8F87_RS09515 (J8F87_09450) yecA 1984087..1984752 (+) 666 WP_000847882.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23991.79 Da        Isoelectric Point: 7.3522

>NTDB_id=484100 J8F87_RS09485 WP_081508827.1 1980347..1981003(+) (letA) [Escherichia coli strain WG5::PA2]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSRQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=484100 J8F87_RS09485 WP_081508827.1 1980347..1981003(+) (letA) [Escherichia coli strain WG5::PA2]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAAGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482