Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   J7U05_RS06015 Genome accession   NZ_CP072443
Coordinates   1154111..1155898 (-) Length   595 a.a.
NCBI ID   WP_116920287.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain S24724     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1149111..1160898
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J7U05_RS05995 (J7U05_05975) - 1150075..1150715 (-) 641 Protein_1126 DNA alkylation repair protein -
  J7U05_RS06000 (J7U05_05980) - 1150907..1151419 (-) 513 WP_002951148.1 GNAT family N-acetyltransferase -
  J7U05_RS06005 (J7U05_05985) - 1151697..1152380 (+) 684 Protein_1128 ISL3 family transposase -
  J7U05_RS06010 (J7U05_05990) cls 1152472..1154022 (-) 1551 WP_193838427.1 cardiolipin synthase -
  J7U05_RS06015 (J7U05_05995) uvrC 1154111..1155898 (-) 1788 WP_116920287.1 excinuclease ABC subunit UvrC Machinery gene
  J7U05_RS06020 (J7U05_06000) - 1155958..1156653 (-) 696 WP_116920288.1 YjjG family noncanonical pyrimidine nucleotidase -
  J7U05_RS06025 (J7U05_06005) - 1156952..1157386 (+) 435 WP_049825679.1 biotin transporter BioY -
  J7U05_RS06030 (J7U05_06010) - 1157621..1158247 (-) 627 WP_014608466.1 ABC transporter permease -
  J7U05_RS06035 (J7U05_06015) - 1158252..1159007 (-) 756 WP_014727588.1 ABC transporter ATP-binding protein -
  J7U05_RS06040 (J7U05_06020) - 1159019..1159936 (-) 918 WP_014727589.1 glycine betaine ABC transporter substrate-binding protein -
  J7U05_RS06045 (J7U05_06025) - 1159933..1160589 (-) 657 WP_041829367.1 ABC transporter permease -

Sequence

Protein


Download         Length: 595 a.a.        Molecular weight: 68761.07 Da        Isoelectric Point: 9.3039

>NTDB_id=483607 J7U05_RS06015 WP_116920287.1 1154111..1155898(-) (uvrC) [Streptococcus thermophilus strain S24724]
MNDLIKHKLELLPNNPGCYLHKDKFGNIIYVGKAKNLKNRVRSYFRGSHDTKTELLVSEIADFEFIVTESNIEALLLEIN
LIQENMPKFNIRLKDGKSYPFIKITKEFYPRLLITRQVKKDGGLYFGPYPDSGAANEIKKLLDRIFPFKKCKNPANKVCF
YYHIGQCNAHTICHTTEDYWQDLVEDVKNFLNGYDDKIVNQLKAKMKDMSDQMEFERAAEYRDLIEAVSTLRTKQRVIRQ
DMQDRDIFGYYVDKGWMCVQVFFVRQGKLIQRDVNMFPYYNDAEEDFLTYMGQFYLDSRHLKPREIFIPGDIDQESVEAL
VGDEVKVFKPQRGEKKQLVNLATKNARVSLTQKFDLLEKDIAKTQGAIENLGKLMGIPTPVRIESFDNSNIMGTSPVSAM
VVFENGKPNKKEYRKYKIKTVEGPDDYASMREVIRRRYSRVKRDGLTPPDLIIMDGGQGQVNVAKDVLRNELNLSIPVAG
LQKNDKHQTNELLFGDPLRVIDLPRQSEEFFLLHRIQDEVHRFAITFHRQVRSKNSFSSKLDGVEGLGPKRKQKLLKNFK
SMTAIQQASVEDIQALGIPEKVAQALLDKLSQDSH

Nucleotide


Download         Length: 1788 bp        

>NTDB_id=483607 J7U05_RS06015 WP_116920287.1 1154111..1155898(-) (uvrC) [Streptococcus thermophilus strain S24724]
ATGAACGATCTGATTAAACATAAGTTGGAATTGCTCCCAAACAACCCGGGATGTTATCTCCATAAGGACAAATTTGGCAA
TATTATCTATGTCGGTAAGGCTAAAAATCTAAAAAATCGTGTGCGTAGCTATTTTCGTGGAAGTCATGATACCAAGACGG
AGCTTCTGGTATCCGAGATTGCAGACTTTGAATTTATCGTTACCGAGTCTAATATCGAGGCCTTGCTTTTGGAAATTAAC
CTCATCCAAGAGAATATGCCCAAATTCAACATCCGCCTCAAGGATGGCAAGTCTTATCCATTTATCAAGATTACTAAGGA
ATTCTATCCAAGGCTCTTGATTACCCGCCAGGTTAAGAAGGATGGTGGTCTCTATTTTGGTCCTTACCCAGACTCTGGTG
CAGCCAATGAAATCAAGAAGCTGTTGGACCGTATTTTCCCCTTTAAGAAATGTAAAAATCCTGCTAACAAGGTCTGTTTC
TATTACCATATTGGCCAATGTAATGCCCACACCATCTGTCACACCACTGAGGACTATTGGCAAGATTTGGTTGAGGATGT
CAAGAATTTTCTAAACGGTTATGATGATAAAATCGTTAACCAGCTTAAGGCCAAGATGAAGGACATGTCTGATCAGATGG
AGTTTGAGCGGGCAGCAGAATATCGAGATCTGATTGAGGCGGTATCGACACTGAGGACCAAGCAAAGGGTTATTCGTCAG
GACATGCAGGACCGTGATATCTTCGGTTACTACGTGGACAAGGGTTGGATGTGTGTTCAAGTTTTCTTTGTTCGCCAAGG
AAAACTCATCCAGCGTGATGTCAATATGTTCCCTTACTATAATGATGCTGAGGAAGATTTTCTGACCTATATGGGTCAAT
TTTACCTGGATAGTCGTCATCTTAAGCCTAGGGAAATTTTTATTCCTGGAGATATTGATCAAGAGTCTGTCGAAGCTCTG
GTCGGAGATGAAGTCAAGGTTTTTAAACCGCAAAGAGGCGAGAAAAAGCAGTTGGTTAATCTGGCAACGAAAAATGCCCG
TGTCAGCCTGACTCAAAAATTTGATCTTCTTGAAAAAGATATAGCCAAGACCCAAGGAGCCATTGAAAATCTAGGCAAAC
TCATGGGAATTCCGACACCGGTTCGCATCGAGTCCTTCGATAACTCTAACATCATGGGAACGAGCCCTGTATCTGCCATG
GTCGTTTTTGAGAACGGCAAACCTAATAAAAAAGAGTACCGCAAATACAAGATTAAGACGGTTGAAGGGCCTGACGATTA
TGCCAGCATGCGTGAGGTCATTCGTCGCCGTTATAGTCGTGTCAAACGTGATGGTCTAACCCCACCAGACCTCATTATCA
TGGATGGTGGTCAAGGTCAGGTCAATGTCGCTAAGGACGTGCTTCGTAATGAGCTGAATCTATCTATCCCGGTTGCAGGT
CTTCAGAAAAATGACAAGCACCAAACCAATGAATTGCTCTTTGGAGATCCTTTGCGAGTCATTGATTTGCCACGTCAATC
CGAGGAATTTTTCCTCCTTCACCGTATTCAGGATGAAGTACACCGCTTTGCCATCACCTTCCATCGACAAGTCCGTAGTA
AGAATAGTTTCAGTTCCAAACTTGATGGCGTGGAGGGGTTGGGACCTAAACGCAAACAAAAACTCCTCAAAAACTTCAAA
TCAATGACGGCTATCCAACAAGCCAGTGTCGAAGACATCCAAGCTCTTGGAATTCCTGAAAAAGTAGCTCAAGCTTTATT
AGATAAGTTGAGCCAAGATAGTCATTAA

Domains

Predicted by InterProScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(375-525)

Helix-hairpin-helix domain (HHH_5)

(540-590)

UvrB/uvrC motif (UVR)

(196-229)

GIY-YIG catalytic domain (GIY-YIG)

(16-87)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

76.142

99.328

0.756
  uvrC Streptococcus pneumoniae R6

75.804

99.328

0.753
  uvrC Streptococcus pneumoniae D39

75.804

99.328

0.753