Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   J7T61_RS06320 Genome accession   NZ_CP072441
Coordinates   1206780..1208567 (-) Length   595 a.a.
NCBI ID   WP_011681323.1    Uniprot ID   Q03K10
Organism   Streptococcus thermophilus strain S24728     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1201780..1213567
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J7T61_RS06295 (J7T61_06295) - 1202141..1203217 (-) 1077 WP_011681318.1 aspartate-semialdehyde dehydrogenase -
  J7T61_RS06300 (J7T61_06300) - 1203578..1204090 (-) 513 WP_002951148.1 GNAT family N-acetyltransferase -
  J7T61_RS06305 - 1204249..1204386 (+) 138 WP_002948564.1 hypothetical protein -
  J7T61_RS06310 (J7T61_06305) - 1204368..1205050 (+) 683 Protein_1189 transposase -
  J7T61_RS06315 (J7T61_06310) cls 1205141..1206691 (-) 1551 WP_171815050.1 cardiolipin synthase -
  J7T61_RS06320 (J7T61_06315) uvrC 1206780..1208567 (-) 1788 WP_011681323.1 excinuclease ABC subunit UvrC Machinery gene
  J7T61_RS06325 (J7T61_06320) - 1208627..1209322 (-) 696 WP_011681324.1 YjjG family noncanonical pyrimidine nucleotidase -
  J7T61_RS06330 (J7T61_06325) sdaAB 1209600..1210271 (+) 672 WP_011681325.1 L-serine ammonia-lyase, iron-sulfur-dependent subunit beta -
  J7T61_RS06335 (J7T61_06330) sdaAA 1210284..1211153 (+) 870 WP_011226205.1 L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha -
  J7T61_RS06340 - 1211337..1211569 (+) 233 Protein_1195 IS30 family transposase -
  J7T61_RS06345 (J7T61_06335) - 1211876..1212310 (-) 435 WP_372429193.1 hypothetical protein -
  J7T61_RS06350 (J7T61_06340) - 1212588..1213372 (-) 785 Protein_1197 ABC transporter permease -

Sequence

Protein


Download         Length: 595 a.a.        Molecular weight: 68470.97 Da        Isoelectric Point: 9.6924

>NTDB_id=483406 J7T61_RS06320 WP_011681323.1 1206780..1208567(-) (uvrC) [Streptococcus thermophilus strain S24728]
MNGLIKHKLELLPSNPGCYLHKDKFGNIIYVGKAKNLKNRVRSYFRGSHDTKTELLVSEIADFEFIVTESNIEALLLEIN
LIQENMPKFNIRLKDGKSYPFIKITKELYPRLLITRQVKKDGGLYFGPYPDSGAANEIKKLLDRIFPFKKCKNPANKVCF
YYHIGQCNAHTICHTTEDYWQGLVEDVKNFLNGHDDKIVNQLKAKMKDMSDQMAFERAAEYRDLIEAVSTLRTKQRVIRQ
DMQDRDIFGYYVDKGWMCVQVFFVRQGKLIQRDVNMFPYYNDAEEDFLTYMGQFYLDSRHLKPKEIFIPGDIDQESVEAL
VGDEVKVFKPKRGEKKQLVNLATKNARVSLTQKFDLLEKDIAKTQGAIENLGKLMGIPTPVRIESFDNSNIMGTSPVSAM
VVFENGKPNKKEYRKYKIKTVEGPDDYASMREVIRRRYSRVKRDGLTPPDLIIMDGGQGQVNVAKDVLRNELNLSIPVAG
LQKNDKHQTNELLFGDPLRVIDLPRQSEEFFLLHRIQDEVHRFAITFHRQVRSKNSFSSKLDGVEGLGPKRKQKLLKNFK
SMTAIQQASVEDIQALGIPKKVAQALLDKLSQDSH

Nucleotide


Download         Length: 1788 bp        

>NTDB_id=483406 J7T61_RS06320 WP_011681323.1 1206780..1208567(-) (uvrC) [Streptococcus thermophilus strain S24728]
ATGAATGGTCTGATTAAACATAAGTTGGAACTGCTCCCAAGCAACCCAGGGTGTTATCTCCACAAGGACAAATTCGGCAA
TATTATTTATGTCGGTAAGGCTAAAAATCTAAAAAATCGTGTGCGTAGCTATTTTCGTGGAAGCCATGATACCAAGACGG
AGCTTTTGGTATCTGAGATTGCAGACTTTGAATTTATCGTAACCGAGTCTAATATCGAGGCCCTGCTTTTGGAAATTAAC
CTCATTCAAGAGAATATGCCCAAATTTAACATTCGCCTCAAGGATGGCAAGTCTTATCCATTTATCAAGATTACTAAGGA
ACTCTATCCAAGGCTCTTGATTACCCGCCAGGTTAAGAAGGATGGTGGTCTCTATTTTGGTCCTTACCCAGACTCTGGTG
CAGCCAATGAAATCAAGAAGCTGTTGGACCGTATTTTCCCCTTTAAGAAATGTAAAAATCCTGCTAACAAGGTCTGTTTC
TATTACCATATTGGCCAATGTAATGCCCACACCATCTGTCACACCACTGAGGACTATTGGCAAGGTTTGGTTGAGGATGT
CAAGAATTTTCTAAACGGTCATGATGATAAAATCGTTAACCAGCTTAAGGCCAAGATGAAGGACATGTCTGATCAGATGG
CGTTTGAGCGGGCAGCAGAATATCGAGATCTGATTGAGGCAGTGTCGACGCTCAGGACCAAACAAAGGGTTATCCGTCAA
GATATGCAGGACCGCGATATTTTTGGCTACTACGTGGACAAGGGCTGGATGTGTGTTCAAGTTTTCTTTGTTCGCCAAGG
AAAACTCATCCAGCGTGATGTCAATATGTTCCCTTACTATAATGATGCTGAGGAAGATTTTCTAACCTATATGGGTCAAT
TTTACTTGGATAGCCGTCATCTCAAGCCTAAGGAGATTTTCATTCCAGGGGACATTGATCAAGAGTCTGTCGAAGCTCTG
GTCGGAGATGAAGTCAAGGTTTTTAAACCGAAAAGAGGCGAGAAAAAGCAGTTGGTTAATCTGGCAACGAAAAATGCCCG
TGTCAGCCTGACTCAAAAATTTGATCTTCTTGAAAAAGATATAGCCAAGACCCAAGGAGCCATTGAAAATCTAGGCAAAC
TCATGGGAATTCCGACACCGGTTCGCATCGAGTCCTTCGATAACTCTAACATCATGGGAACGAGCCCTGTATCTGCCATG
GTCGTTTTTGAGAACGGCAAACCTAATAAAAAAGAGTACCGCAAATACAAGATTAAGACGGTTGAAGGGCCTGACGATTA
TGCCAGCATGCGTGAGGTCATTCGTCGCCGTTATAGTCGTGTCAAACGTGATGGTCTAACCCCACCAGACCTCATTATCA
TGGATGGTGGTCAAGGTCAGGTCAATGTCGCTAAGGACGTGCTTCGTAATGAGCTGAATCTATCTATCCCGGTTGCAGGT
CTTCAGAAAAATGACAAGCACCAAACCAATGAATTGCTCTTTGGAGATCCTTTGCGAGTCATTGATTTGCCACGTCAATC
CGAGGAGTTTTTCCTCCTTCACCGTATTCAGGATGAAGTACACCGCTTTGCCATCACCTTCCATCGACAAGTCCGTAGTA
AGAATAGTTTCAGTTCCAAACTTGATGGCGTGGAGGGGTTGGGACCTAAACGCAAACAAAAACTCCTCAAAAACTTCAAA
TCAATGACAGCTATCCAACAAGCCAGTGTCGAAGACATCCAAGCTCTTGGAATTCCTAAAAAAGTAGCTCAAGCTTTATT
AGATAAGTTGAGCCAAGATAGTCATTAA

Domains

Predicted by InterProScan.

GIY-YIG catalytic domain (GIY-YIG)

(16-87)

UvrB/uvrC motif (UVR)

(196-229)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(375-525)

Helix-hairpin-helix domain (HHH_5)

(540-590)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q03K10

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

75.804

99.328

0.753
  uvrC Streptococcus pneumoniae R6

75.465

99.328

0.75
  uvrC Streptococcus pneumoniae D39

75.465

99.328

0.75