Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   J7U23_RS06440 Genome accession   NZ_CP072435
Coordinates   1235489..1237276 (-) Length   595 a.a.
NCBI ID   WP_372589850.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain S24736     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1230489..1242276
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J7U23_RS06415 (J7U23_06360) - 1231453..1232093 (-) 641 Protein_1210 DNA alkylation repair protein -
  J7U23_RS06420 (J7U23_06365) - 1232286..1232798 (-) 513 WP_022096706.1 GNAT family N-acetyltransferase -
  J7U23_RS06425 - 1232957..1233094 (+) 138 WP_372433441.1 hypothetical protein -
  J7U23_RS06430 (J7U23_06370) - 1233076..1233758 (+) 683 Protein_1213 transposase -
  J7U23_RS06435 (J7U23_06375) cls 1233850..1235400 (-) 1551 WP_179970536.1 cardiolipin synthase -
  J7U23_RS06440 (J7U23_06380) uvrC 1235489..1237276 (-) 1788 WP_372589850.1 excinuclease ABC subunit UvrC Machinery gene
  J7U23_RS06445 (J7U23_06385) - 1237336..1238031 (-) 696 Protein_1216 YjjG family noncanonical pyrimidine nucleotidase -
  J7U23_RS06450 (J7U23_06390) - 1238309..1238659 (+) 351 Protein_1217 serine dehydratase beta chain -
  J7U23_RS06455 (J7U23_06395) prx 1238855..1239043 (-) 189 WP_372589851.1 hypothetical protein Regulator
  J7U23_RS06460 (J7U23_06400) - 1239308..1239745 (-) 438 WP_372589852.1 hypothetical protein -
  J7U23_RS06465 - 1240008..1240115 (-) 108 Protein_1220 RNA-binding protein -
  J7U23_RS06470 (J7U23_06410) - 1240119..1240599 (-) 481 Protein_1221 NUDIX hydrolase -
  J7U23_RS06475 (J7U23_06415) - 1240948..1241904 (-) 957 WP_260214219.1 hypothetical protein -

Sequence

Protein


Download         Length: 595 a.a.        Molecular weight: 68635.02 Da        Isoelectric Point: 9.3815

>NTDB_id=482786 J7U23_RS06440 WP_372589850.1 1235489..1237276(-) (uvrC) [Streptococcus thermophilus strain S24736]
MNDLIKHKLELLPNNPGCYLHKDKFGNIIYVGKAKNLKNRVRSYFRGSHDTKTELLVSEIADFEFIVTESNIEALLLEIN
LIQENMPKFNIRLKDGKSYPFIKITKELYPRLLITRQVKKDGGLYFGPYPDSGAANEIKKLLDRIFPFKKCKNPANKVCF
YYHIGQCNAHTICHTTEDYWQGLVEDVKNFLNGYDDKIVNQLKAKMKDMSDQMEFERAAEYRDLIEAVSTLRTKQRVIRQ
DMQDRDIFGYYVDKGWMCVQVFFVRQGKLIQRDVNIFPYYNDAEEDFLTYMGQFYLDSRHLKPKEIFIPGDIDQESVEAL
VGDEVKVFKPQRGEKKQLVNLATKNARVSLTQKFDLLEKDIAKTQGAIENLGKLMGIPTPVRIESFDNSNIMGTSPVSAM
VVFENGKPNKKEYRKYKIKTVEGPDDYASMREVIRRRYSRVKRDGLTPPDLIIMDGGQGQVNVAKDVLRNELNLSIPVAG
LQKNDKHQTNELLFGDPLRVIDLPRQSEEFFLLHRIQDEVHRFAITFHRQVRSKNSFSSKLDGVEGLGPKRKQKLLKNFK
SMIAIQQASVEDIQALGIPEKVAQALLDKLSQDSH

Nucleotide


Download         Length: 1788 bp        

>NTDB_id=482786 J7U23_RS06440 WP_372589850.1 1235489..1237276(-) (uvrC) [Streptococcus thermophilus strain S24736]
ATGAACGATCTGATTAAACATAAGTTGGAATTACTCCCAAACAACCCGGGATGTTATCTCCATAAGGACAAATTTGGCAA
TATTATCTATGTCGGTAAGGCTAAAAATCTAAAAAATCGTGTGCGTAGCTATTTTCGTGGAAGTCATGATACCAAGACGG
AGCTTCTGGTATCCGAGATTGCAGACTTTGAATTTATCGTTACCGAGTCTAATATCGAGGCCTTGCTTTTGGAAATTAAC
CTCATCCAAGAGAATATGCCCAAATTCAACATCCGCCTCAAGGATGGCAAGTCTTATCCATTTATCAAGATTACTAAGGA
ACTCTATCCAAGGCTCTTGATTACCCGCCAGGTTAAGAAGGATGGTGGTCTCTATTTTGGTCCTTACCCAGACTCTGGTG
CAGCCAATGAAATCAAGAAGCTGTTGGACCGTATTTTCCCCTTTAAGAAATGTAAAAATCCTGCTAACAAGGTCTGTTTC
TATTACCATATTGGCCAATGTAATGCCCACACCATCTGTCACACCACTGAGGACTATTGGCAAGGTTTGGTTGAGGATGT
CAAGAATTTTCTAAACGGTTATGATGATAAAATCGTTAACCAGCTTAAGGCCAAGATGAAGGATATGTCTGACCAGATGG
AGTTTGAGCGGGCAGCAGAATATCGAGATCTGATTGAGGCGGTATCGACACTGAGGACCAAGCAAAGGGTTATCCGTCAG
GACATGCAGGATCGTGATATTTTCGGTTACTACGTGGACAAGGGTTGGATGTGTGTTCAAGTTTTCTTTGTTCGCCAAGG
AAAACTCATCCAGCGTGATGTCAATATATTCCCTTACTATAATGATGCTGAGGAAGATTTTCTAACCTATATGGGTCAAT
TTTACTTGGATAGCCGTCATCTCAAGCCTAAGGAGATTTTCATTCCAGGGGACATTGATCAAGAGTCTGTCGAAGCTCTG
GTCGGAGATGAAGTCAAGGTTTTTAAACCGCAAAGAGGCGAGAAAAAGCAGTTGGTTAATCTAGCAACGAAAAATGCCCG
TGTCAGCCTGACTCAAAAATTTGATCTTCTTGAAAAAGATATAGCCAAGACCCAAGGAGCCATTGAAAATCTAGGCAAAC
TCATGGGAATTCCGACACCGGTTCGCATCGAGTCCTTCGATAACTCTAACATCATGGGAACGAGCCCTGTATCTGCCATG
GTCGTTTTTGAGAACGGCAAACCTAATAAAAAAGAGTACCGCAAATACAAGATTAAGACGGTTGAAGGGCCTGACGATTA
TGCCAGCATGCGTGAGGTCATTCGTCGCCGTTATAGTCGTGTCAAACGTGATGGTCTAACCCCACCAGACCTCATTATCA
TGGATGGTGGTCAAGGTCAGGTCAATGTCGCTAAGGACGTGCTTCGTAATGAGCTGAATCTATCTATCCCGGTTGCAGGT
CTTCAGAAAAATGACAAGCACCAAACCAATGAATTGCTCTTTGGAGATCCTTTGCGAGTCATTGATTTGCCACGTCAATC
CGAGGAGTTTTTCCTCCTTCACCGTATTCAGGATGAAGTACACCGCTTTGCCATCACCTTCCATCGACAAGTCCGTAGTA
AGAATAGTTTCAGTTCCAAACTTGATGGCGTGGAGGGGTTGGGACCTAAACGCAAACAAAAACTCCTCAAAAACTTCAAA
TCAATGATAGCTATCCAACAAGCCAGTGTCGAAGACATCCAAGCTCTTGGAATTCCTGAAAAAGTAGCTCAAGCTTTATT
AGATAAGTTGAGCCAAGATAGTCATTAA

Domains

Predicted by InterProScan.

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(375-525)

Helix-hairpin-helix domain (HHH_5)

(540-590)

GIY-YIG catalytic domain (GIY-YIG)

(16-87)

UvrB/uvrC motif (UVR)

(196-229)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

75.973

99.328

0.755
  uvrC Streptococcus pneumoniae R6

75.635

99.328

0.751
  uvrC Streptococcus pneumoniae D39

75.635

99.328

0.751