Detailed information NTG0482591

Bioinformatically predicted

Overview

• Name: pilR
• Type: Regulator
• Locus tag: ICG51_RS05185
• Genome accession: NZ_CP061497
• Coordinates: 1090198..1091652 (-)
• Length: 484 a.a.
• NCBI ID: WP_190281944.1
• Uniprot ID: A0A7H1RKG6
• Organism: Thermomonas sp. XSG
• Function: regulate pilin expression (predicted from homology) Competence regulation

Genomic Context

Location: 1085198..1096652

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
ICG51_RS05170 (ICG51_001035)	sucD	1086269..1087144 (-)	876	WP_187569472.1	succinate--CoA ligase subunit alpha	-
ICG51_RS05175 (ICG51_001036)	sucC	1087255..1088424 (-)	1170	WP_190281942.1	ADP-forming succinate--CoA ligase subunit beta	-
ICG51_RS05180 (ICG51_001037)	-	1088569..1090182 (+)	1614	WP_190281943.1	ATP-binding protein	-
ICG51_RS05185 (ICG51_001038)	pilR	1090198..1091652 (-)	1455	WP_190281944.1	sigma-54 dependent transcriptional regulator	Regulator
ICG51_RS14345	-	1092100..1092189 (+)	90	Protein_1012	prepilin-type N-terminal cleavage/methylation domain-containing protein	-
ICG51_RS14350	-	1092583..1092720 (+)	138	Protein_1013	prepilin-type N-terminal cleavage/methylation domain-containing protein	-
ICG51_RS05200 (ICG51_001041)	-	1093072..1094955 (+)	1884	WP_190281947.1	hypothetical protein	-

Sequence

Protein

• Length: 484 a.a.
• Molecular weight: 52043.99 Da
• Isoelectric Point: 6.7732

>NTDB_id=482591 ICG51_RS05185 WP_190281944.1 1090198..1091652(-) (pilR) [Thermomonas sp. XSG]
MSIPPRSPQANAPICALVVDDERDIRELLVLTLGRMGLKCDTASSLHDARALLKRNQYALCLTDMRLADGSGIELVQEIS
QLYAQTPVAMITAFGNQEAAVGALKAGAFDFVSKPVDLAVLRGLVQHALKLVPAALAAGEEAPKRAPVTGAVASRLLGQS
AAMAELRATLGKVARSQAPVYIAGESGVGKELVARTIHDEGMRAAGPFVPVNCGAIPTELMESEFFGHRKGSFTGAHADK
TGLFQAAEGGTLFLDEIAELPMSMQVKLLRAIQEKSVRPVGANTEVPVDVRILSATHKNLAALVEEGRFRHDLYYRINVI
ELRVPPLRERREDLPVLVDAILTRLAAAQGRLRPELHPDAMEALAHYTFPGNVRELENILERAFALADDDGIRAADLRLP
EARPAAPPPSLAAQASAAAATLDPSLIDPRESASSALPGFIEEVERKAIEQALVDNRYNKTKTAAQLGITFRALRYKLKK
LGID

Nucleotide

• Length: 1455 bp

>NTDB_id=482591 ICG51_RS05185 WP_190281944.1 1090198..1091652(-) (pilR) [Thermomonas sp. XSG]
ATGAGTATTCCCCCCCGCAGCCCCCAAGCCAACGCCCCGATCTGTGCCCTGGTGGTCGATGACGAGCGCGACATCCGCGA
ACTGCTGGTGCTGACCCTGGGGCGGATGGGGCTGAAATGCGACACGGCCTCGTCCCTCCACGACGCGCGCGCGCTGCTCA
AGCGCAACCAGTACGCGCTGTGCCTGACCGACATGCGCCTGGCCGACGGTTCCGGCATCGAGCTGGTGCAGGAAATCTCG
CAGCTCTATGCGCAGACGCCGGTGGCGATGATCACCGCGTTCGGCAACCAGGAGGCGGCGGTGGGCGCCCTGAAGGCCGG
TGCCTTCGACTTCGTCAGCAAGCCGGTTGACCTGGCGGTGCTGCGCGGGCTGGTCCAGCACGCGCTGAAGCTGGTGCCAG
CGGCTCTTGCCGCTGGCGAGGAAGCGCCCAAAAGGGCGCCGGTGACCGGTGCGGTGGCCTCGCGGCTGCTGGGACAGTCC
GCGGCGATGGCCGAGCTGCGCGCCACTCTGGGCAAGGTGGCCCGCAGCCAGGCGCCGGTCTACATCGCGGGCGAGTCCGG
CGTGGGCAAGGAGCTGGTGGCGCGCACCATCCATGACGAGGGGATGCGCGCGGCCGGGCCGTTCGTGCCGGTCAACTGCG
GCGCGATCCCGACCGAGCTGATGGAAAGCGAGTTCTTCGGCCATCGCAAGGGCAGTTTCACCGGGGCCCATGCCGACAAG
ACCGGCCTGTTCCAGGCGGCCGAGGGCGGCACGCTGTTCCTGGACGAGATCGCCGAGCTGCCGATGTCCATGCAGGTCAA
GCTGCTGCGTGCGATCCAGGAGAAGTCGGTGCGGCCGGTGGGCGCCAATACCGAGGTGCCGGTGGACGTGCGGATCCTGT
CCGCCACCCACAAGAACCTGGCCGCGCTGGTGGAGGAGGGCAGGTTCCGCCACGACCTGTACTACCGCATCAACGTCATC
GAACTGCGGGTGCCGCCGCTGCGCGAGCGCCGCGAGGACCTGCCTGTGCTGGTGGACGCCATCCTCACCCGTTTGGCCGC
AGCGCAGGGGCGGCTGCGGCCGGAGCTGCATCCGGACGCGATGGAGGCGCTGGCGCACTACACCTTCCCCGGCAACGTGC
GCGAGCTGGAGAACATCCTCGAGCGCGCCTTCGCGCTGGCCGACGACGACGGCATCCGCGCCGCCGACCTGCGCCTGCCC
GAAGCCCGCCCGGCGGCGCCGCCACCGTCGCTGGCGGCGCAGGCCAGTGCAGCGGCCGCCACCCTGGACCCCAGCCTGAT
CGATCCGCGCGAATCCGCCAGCAGTGCGCTGCCGGGCTTCATCGAGGAAGTGGAGCGCAAGGCGATCGAGCAGGCGCTGG
TCGACAACCGCTACAACAAGACCAAGACCGCCGCCCAGCTGGGCATCACCTTCCGTGCGCTGCGCTACAAGCTGAAGAAG
CTGGGCATCGACTGA

Domains

Predicted by InterproScan.

• Bacterial regulatory protein, Fis family (HTH_8) (441-481)

• Sigma-54 interaction domain (Sigma54_activat) (156-322)

• Response regulator receiver domain (Response_reg) (17-123)

3D structure

• AlphaFold DB: A0A7H1RKG6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilR	Pseudomonas aeruginosa PAK	60.851	97.107	0.591
pilR	Acinetobacter baumannii strain A118	46.269	96.901	0.448