Detailed information NTG0482591

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: J7U07_RS07365
• Genome accession: NZ_CP072433
• Coordinates: 1418427..1420667 (-)
• Length: 746 a.a.
• NCBI ID: WP_372588677.1
• Uniprot ID: -
• Organism: Streptococcus thermophilus strain S24743
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1413427..1425667

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J7U07_RS07345 (J7U07_07245)	-	1414291..1415151 (-)	861	WP_011226395.1	methionyl aminopeptidase	-
J7U07_RS07350 (J7U07_07250)	spxR	1415195..1416475 (-)	1281	WP_372588676.1	CBS-HotDog domain-containing transcription factor SpxR	-
J7U07_RS07355 (J7U07_07255)	-	1416468..1417013 (-)	546	WP_014608611.1	GNAT family N-acetyltransferase	-
J7U07_RS07360 (J7U07_07260)	-	1417079..1418341 (-)	1263	WP_014608612.1	UDP-N-acetylglucosamine 1-carboxyvinyltransferase	-
J7U07_RS07365 (J7U07_07265)	comEC/celB	1418427..1420667 (-)	2241	WP_372588677.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
J7U07_RS07370 (J7U07_07270)	comEA	1420657..1421352 (-)	696	WP_014608614.1	helix-hairpin-helix domain-containing protein	Machinery gene
J7U07_RS07375 (J7U07_07275)	-	1421460..1422215 (-)	756	WP_179970604.1	1-acyl-sn-glycerol-3-phosphate acyltransferase	-
J7U07_RS07380	-	1422415..1422948 (+)	534	WP_014608615.1	polysaccharide deacetylase family protein	-
J7U07_RS07385	-	1423057..1423206 (+)	150	WP_014608616.1	polysaccharide deacetylase	-
J7U07_RS07390 (J7U07_07285)	-	1423256..1424020 (+)	765	WP_014608617.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
J7U07_RS07395 (J7U07_07290)	-	1424024..1424293 (+)	270	WP_011226404.1	GIY-YIG nuclease family protein	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84852.78 Da
• Isoelectric Point: 9.8818

>NTDB_id=482591 J7U07_RS07365 WP_372588677.1 1418427..1420667(-) (comEC/celB) [Streptococcus thermophilus strain S24743]
MWLKKAPINLFSLALLIVALYFTIFVSNFYAIGTFVFLVICFLRHHWKNRAALKLVGLIGGFFLVYFLFLYHIAIMQDKQ
TPAEIHQVTLVADTLSVNGERLSAIGKSNGQTYQVFYRLKSDKEQHFFKTTSQTLVLKGKIKLSSATGQRNFQGFDYKSY
LASQGIYRIAQIERLEHAVTPKSISPIAFFHQLRRKALVHIQTHFPNPMRHYMTGLLFGYLDKEFDEQSQLYTSLGIIHL
FALSGMQVGFFLGWFRYGLLRLGLPKNYILAILLPFSIFYGLMTGWTASVLRSLIQSLLAECGIKKLNNMGITLLLFFLV
LPHFLLTVGGVLSCSYAFLLCLFNFEEMPSFKKSIYMSLVLSLGTLPFLTYYYGTFEPLSLILTAIFSLVFDSFLLPVLT
VLFTLSGMVIFSQFNTLFEWMEFFLTWVQSWGVQPLILGKPSLFQFVSMIFVLVLLFDFWKKPQFRISLLMIFSLLMVWV
KHPLINEVTVVDVGQGDSIFLRSMKGETVLIDVGGKVTFGSKEKWQEGSQTSNAEKTLIPYLQARGVSQIDYLVLTHTDT
DHIGDLEVVAKRFKIKKICVSEGALTKPSFAKRIRFLKCPVRTLKAGDKLPMMGSNLQVLYPNKIGDGGNNDSLVLYGKL
LGTSFLFTGDLEKEGEEELMTSYPNLKVRVLKAGHHGSKDSSSEAFLDQLKPSLALVSAGENNRYKHPNDETLERFKERH
IKVLRTDQDGAIRFKGWFQLSSETVR

Nucleotide

• Length: 2241 bp

>NTDB_id=482591 J7U07_RS07365 WP_372588677.1 1418427..1420667(-) (comEC/celB) [Streptococcus thermophilus strain S24743]
ATGTGGCTTAAAAAAGCTCCAATCAATCTTTTTTCCCTAGCGCTTTTAATAGTTGCTCTTTATTTTACTATTTTTGTATC
TAATTTCTATGCTATTGGGACTTTTGTCTTTCTGGTGATATGTTTTTTGAGGCATCATTGGAAGAATAGAGCAGCTCTAA
AGTTGGTGGGACTTATAGGTGGTTTCTTTTTGGTCTACTTTTTATTTTTATACCATATAGCTATCATGCAAGATAAACAA
ACTCCTGCTGAAATTCATCAGGTGACACTGGTTGCAGATACGCTCTCAGTTAATGGTGAGCGATTATCAGCAATCGGGAA
GTCAAATGGACAAACCTATCAGGTCTTTTACCGGCTAAAATCTGATAAGGAGCAGCATTTTTTTAAGACTACTAGTCAAA
CGCTTGTTTTAAAAGGGAAAATAAAGTTGTCCTCGGCAACTGGTCAACGTAATTTTCAAGGCTTTGATTATAAGTCTTAT
CTAGCTAGTCAGGGCATTTATAGGATTGCTCAGATTGAGCGTCTGGAACATGCCGTAACCCCAAAATCGATATCTCCAAT
AGCTTTTTTTCATCAATTGAGGAGGAAGGCTCTAGTTCATATTCAGACGCATTTTCCTAATCCGATGAGACACTACATGA
CAGGACTGCTCTTTGGGTATTTGGACAAGGAGTTTGATGAGCAGAGTCAACTCTACACTAGCTTGGGGATTATTCATCTT
TTTGCGCTATCGGGTATGCAGGTTGGATTTTTTCTTGGCTGGTTTCGCTATGGACTTCTCCGTTTGGGGCTTCCCAAAAA
TTATATCCTTGCTATCTTATTACCTTTTTCGATTTTCTATGGCTTAATGACTGGTTGGACGGCTTCGGTCTTACGTTCTT
TGATTCAAAGCCTCTTGGCTGAGTGTGGTATTAAAAAACTGAACAATATGGGCATAACGCTACTTCTATTTTTTCTAGTC
TTGCCTCATTTTCTTTTAACGGTAGGAGGTGTTTTAAGTTGTTCTTATGCCTTCTTGTTGTGTTTATTTAATTTTGAGGA
GATGCCGTCCTTTAAAAAGTCAATTTATATGAGTTTAGTATTGAGTCTTGGGACTTTGCCTTTTTTGACCTACTATTATG
GAACTTTTGAACCATTGAGTTTGATTCTGACGGCAATCTTCTCTCTAGTTTTTGATAGCTTTCTCTTACCTGTCTTAACA
GTACTTTTTACACTTTCAGGAATGGTAATTTTTTCTCAATTTAACACACTTTTTGAATGGATGGAGTTCTTTTTGACTTG
GGTACAATCTTGGGGAGTCCAGCCATTGATTTTAGGAAAACCTAGCTTGTTTCAGTTTGTCTCAATGATATTTGTATTGG
TTTTGCTCTTTGATTTTTGGAAAAAGCCTCAGTTTAGAATATCCCTCTTGATGATTTTTAGTCTTTTGATGGTCTGGGTC
AAACATCCTTTAATAAATGAAGTAACGGTGGTCGACGTTGGTCAAGGAGATAGTATTTTTTTAAGGAGTATGAAAGGTGA
AACGGTCCTAATAGATGTAGGTGGCAAGGTGACTTTCGGCTCTAAGGAAAAATGGCAAGAGGGGAGCCAGACGAGTAATG
CGGAGAAAACCTTAATTCCCTATCTACAGGCAAGGGGAGTGTCTCAAATTGACTATCTGGTTCTGACTCATACGGATACA
GACCATATTGGTGATTTGGAGGTAGTGGCTAAACGGTTTAAGATTAAGAAAATTTGTGTCAGTGAGGGGGCTTTGACTAA
GCCTAGTTTTGCCAAACGTATTCGATTTCTTAAATGTCCCGTTCGCACTTTAAAGGCTGGTGATAAGCTGCCTATGATGG
GAAGTAACCTACAGGTTCTTTATCCCAATAAAATTGGTGATGGTGGTAACAATGATTCACTTGTTCTCTATGGAAAGTTA
TTGGGAACCAGTTTTCTATTTACTGGTGATTTGGAAAAAGAAGGAGAAGAGGAATTGATGACTAGCTATCCAAATTTAAA
AGTAAGGGTCCTCAAAGCAGGACATCACGGTTCTAAAGACTCTTCATCAGAAGCTTTTTTGGACCAGCTAAAGCCATCAC
TTGCTCTTGTCTCAGCAGGTGAAAATAATCGTTATAAGCATCCAAATGATGAAACATTAGAGCGTTTCAAAGAACGTCAC
ATTAAGGTTTTACGCACAGACCAGGATGGTGCCATTCGGTTTAAGGGATGGTTCCAACTATCAAGTGAAACTGTCCGATA
A

Domains

Predicted by InterProScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-699)

• Domain of unknown function (DUF4131) (DUF4131) (29-170)

• Competence protein (Competence) (216-462)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	47.453	100	0.475
comEC/celB	Streptococcus mitis SK321	46.586	100	0.466
comEC/celB	Streptococcus pneumoniae TIGR4	45.649	100	0.457
comEC/celB	Streptococcus pneumoniae Rx1	45.382	100	0.454
comEC/celB	Streptococcus pneumoniae D39	45.382	100	0.454
comEC/celB	Streptococcus pneumoniae R6	45.382	100	0.454
comEC	Lactococcus lactis subsp. cremoris KW2	44.828	97.185	0.436