Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   J7U00_RS03805 Genome accession   NZ_CP072431
Coordinates   714883..716670 (+) Length   595 a.a.
NCBI ID   WP_011681323.1    Uniprot ID   Q03K10
Organism   Streptococcus thermophilus strain S24745     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 709883..721670
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J7U00_RS03775 (J7U00_03780) - 710047..710616 (+) 570 WP_014727594.1 hypothetical protein -
  J7U00_RS03780 - 710820..711052 (-) 233 Protein_738 IS30 family transposase -
  J7U00_RS03785 (J7U00_03785) sdaAA 711236..712105 (-) 870 WP_011226205.1 L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha -
  J7U00_RS03790 (J7U00_03790) sdaAB 712118..712789 (-) 672 WP_011681325.1 L-serine ammonia-lyase, iron-sulfur-dependent subunit beta -
  J7U00_RS03795 (J7U00_03795) - 712970..713905 (+) 936 WP_138496752.1 IS30 family transposase -
  J7U00_RS03800 (J7U00_03800) - 714128..714823 (+) 696 WP_011681324.1 YjjG family noncanonical pyrimidine nucleotidase -
  J7U00_RS03805 (J7U00_03805) uvrC 714883..716670 (+) 1788 WP_011681323.1 excinuclease ABC subunit UvrC Machinery gene
  J7U00_RS03810 (J7U00_03810) cls 716759..718309 (+) 1551 WP_171073573.1 cardiolipin synthase -
  J7U00_RS03815 (J7U00_03815) - 718400..719082 (-) 683 Protein_745 transposase -
  J7U00_RS03820 - 719064..719201 (-) 138 WP_002948564.1 hypothetical protein -
  J7U00_RS03825 (J7U00_03820) - 719360..719872 (+) 513 WP_002951148.1 GNAT family N-acetyltransferase -
  J7U00_RS03830 (J7U00_03825) - 720233..721309 (+) 1077 WP_014608459.1 aspartate-semialdehyde dehydrogenase -

Sequence

Protein


Download         Length: 595 a.a.        Molecular weight: 68470.97 Da        Isoelectric Point: 9.6924

>NTDB_id=482476 J7U00_RS03805 WP_011681323.1 714883..716670(+) (uvrC) [Streptococcus thermophilus strain S24745]
MNGLIKHKLELLPSNPGCYLHKDKFGNIIYVGKAKNLKNRVRSYFRGSHDTKTELLVSEIADFEFIVTESNIEALLLEIN
LIQENMPKFNIRLKDGKSYPFIKITKELYPRLLITRQVKKDGGLYFGPYPDSGAANEIKKLLDRIFPFKKCKNPANKVCF
YYHIGQCNAHTICHTTEDYWQGLVEDVKNFLNGHDDKIVNQLKAKMKDMSDQMAFERAAEYRDLIEAVSTLRTKQRVIRQ
DMQDRDIFGYYVDKGWMCVQVFFVRQGKLIQRDVNMFPYYNDAEEDFLTYMGQFYLDSRHLKPKEIFIPGDIDQESVEAL
VGDEVKVFKPKRGEKKQLVNLATKNARVSLTQKFDLLEKDIAKTQGAIENLGKLMGIPTPVRIESFDNSNIMGTSPVSAM
VVFENGKPNKKEYRKYKIKTVEGPDDYASMREVIRRRYSRVKRDGLTPPDLIIMDGGQGQVNVAKDVLRNELNLSIPVAG
LQKNDKHQTNELLFGDPLRVIDLPRQSEEFFLLHRIQDEVHRFAITFHRQVRSKNSFSSKLDGVEGLGPKRKQKLLKNFK
SMTAIQQASVEDIQALGIPKKVAQALLDKLSQDSH

Nucleotide


Download         Length: 1788 bp        

>NTDB_id=482476 J7U00_RS03805 WP_011681323.1 714883..716670(+) (uvrC) [Streptococcus thermophilus strain S24745]
ATGAATGGTCTGATTAAACATAAGTTGGAACTGCTCCCAAGCAACCCAGGGTGTTATCTCCACAAGGACAAATTCGGCAA
TATTATTTATGTCGGTAAGGCTAAAAATCTAAAAAATCGTGTGCGTAGCTATTTTCGTGGAAGCCATGATACCAAGACGG
AGCTTTTGGTATCTGAGATTGCAGACTTTGAATTTATCGTAACCGAGTCTAATATCGAGGCCCTGCTTTTGGAAATTAAC
CTCATTCAAGAGAATATGCCCAAATTTAACATTCGCCTCAAGGATGGCAAGTCTTATCCATTTATCAAGATTACTAAGGA
ACTCTATCCAAGGCTCTTGATTACCCGCCAGGTTAAGAAGGATGGTGGTCTCTATTTTGGTCCTTACCCAGACTCTGGTG
CAGCCAATGAAATCAAGAAGCTGTTGGACCGTATTTTCCCCTTTAAGAAATGTAAAAATCCTGCTAACAAGGTCTGTTTC
TATTACCATATTGGCCAATGTAATGCCCACACCATCTGTCACACCACTGAGGACTATTGGCAAGGTTTGGTTGAGGATGT
CAAGAATTTTCTAAACGGTCATGATGATAAAATCGTTAACCAGCTTAAGGCCAAGATGAAGGACATGTCTGATCAGATGG
CGTTTGAGCGGGCAGCAGAATATCGAGATCTGATTGAGGCAGTGTCGACGCTCAGGACCAAACAAAGGGTTATCCGTCAA
GATATGCAGGACCGCGATATTTTTGGCTACTACGTGGACAAGGGCTGGATGTGTGTTCAAGTTTTCTTTGTTCGCCAAGG
AAAACTCATCCAGCGTGATGTCAATATGTTCCCTTACTATAATGATGCTGAGGAAGATTTTCTAACCTATATGGGTCAAT
TTTACTTGGATAGCCGTCATCTCAAGCCTAAGGAGATTTTCATTCCAGGGGACATTGATCAAGAGTCTGTCGAAGCTCTG
GTCGGAGATGAAGTCAAGGTTTTTAAACCGAAAAGAGGCGAGAAAAAGCAGTTGGTTAATCTGGCAACGAAAAATGCCCG
TGTCAGCCTGACTCAAAAATTTGATCTTCTTGAAAAAGATATAGCCAAGACCCAAGGAGCCATTGAAAATCTAGGCAAAC
TCATGGGAATTCCGACACCGGTTCGCATCGAGTCCTTCGATAACTCTAACATCATGGGAACGAGCCCTGTATCTGCCATG
GTCGTTTTTGAGAACGGCAAACCTAATAAAAAAGAGTACCGCAAATACAAGATTAAGACGGTTGAAGGTCCTGACGATTA
TGCCAGCATGCGTGAGGTCATTCGTCGCCGTTATAGTCGTGTCAAACGTGATGGTCTAACCCCACCAGACCTCATTATCA
TGGATGGTGGTCAAGGTCAGGTCAATGTCGCTAAGGACGTGCTTCGTAATGAGCTGAATCTATCTATCCCGGTTGCAGGT
CTTCAGAAAAATGACAAGCACCAAACCAATGAATTGCTCTTTGGAGATCCTTTGCGAGTCATTGATTTGCCACGTCAATC
CGAGGAGTTTTTCCTCCTTCACCGTATTCAGGATGAAGTACACCGCTTTGCCATCACCTTCCATCGACAAGTCCGTAGTA
AGAATAGTTTCAGTTCCAAACTTGATGGCGTGGAGGGGTTGGGACCTAAACGCAAACAAAAACTCCTCAAAAACTTCAAA
TCAATGACAGCTATCCAACAAGCCAGTGTCGAAGACATCCAAGCTCTTGGAATTCCTAAAAAAGTAGCTCAAGCTTTATT
AGATAAGTTGAGCCAAGATAGTCATTAA

Domains

Predicted by InterProScan.

GIY-YIG catalytic domain (GIY-YIG)

(16-87)

UvrB/uvrC motif (UVR)

(196-229)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(375-525)

Helix-hairpin-helix domain (HHH_5)

(540-590)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q03K10

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

75.804

99.328

0.753
  uvrC Streptococcus pneumoniae R6

75.465

99.328

0.75
  uvrC Streptococcus pneumoniae D39

75.465

99.328

0.75