Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   J7U00_RS03140 Genome accession   NZ_CP072431
Coordinates   589372..590016 (+) Length   214 a.a.
NCBI ID   WP_002951384.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain S24745     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 584372..595016
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J7U00_RS03120 (J7U00_03135) stkP/pknB 584747..586618 (+) 1872 WP_014621795.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  J7U00_RS03125 - 587255..587422 (+) 168 WP_014608530.1 potassium channel family protein -
  J7U00_RS03130 (J7U00_03145) liaF 587677..588375 (+) 699 WP_011226289.1 cell wall-active antibiotics response protein LiaF -
  J7U00_RS03135 (J7U00_03150) - 588372..589382 (+) 1011 WP_011226288.1 sensor histidine kinase -
  J7U00_RS03140 (J7U00_03155) vraR 589372..590016 (+) 645 WP_002951384.1 response regulator transcription factor Regulator
  J7U00_RS03155 (J7U00_03170) rimM 590562..591080 (+) 519 WP_011226286.1 ribosome maturation factor RimM -
  J7U00_RS03160 (J7U00_03175) trmD 591070..591789 (+) 720 WP_002951382.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  J7U00_RS03165 (J7U00_03180) - 591791..592789 (+) 999 WP_011226284.1 NAD(P)/FAD-dependent oxidoreductase -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24048.39 Da        Isoelectric Point: 4.5864

>NTDB_id=482474 J7U00_RS03140 WP_002951384.1 589372..590016(+) (vraR) [Streptococcus thermophilus strain S24745]
MSNKINVILVDDHEMVRLGLKSFLNLQGDVEVVGEAENGREGVDLALELRPDVVVMDLVMPELDGVQATLELLKEWPEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNSIRKVYRGEEAIETEVDNKIKYHDSHPNLHDDLTARERDILALL
AKGYDNQTIANELFISLKTVKTHVSNILGKLNVDDRTQAVVYAFRHHLVSQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=482474 J7U00_RS03140 WP_002951384.1 589372..590016(+) (vraR) [Streptococcus thermophilus strain S24745]
ATGTCGAATAAGATTAATGTAATTTTGGTAGATGATCATGAAATGGTTCGTTTAGGCCTTAAGAGTTTCTTGAATCTCCA
AGGAGATGTAGAAGTGGTTGGAGAGGCAGAAAACGGCCGTGAGGGTGTCGATCTTGCCCTGGAGCTACGACCAGATGTCG
TTGTTATGGACCTTGTTATGCCTGAGCTAGATGGTGTTCAGGCGACTTTGGAATTGCTAAAAGAATGGCCTGAAGCTAAG
ATTCTAGTTTTGACCAGCTATTTGGACAATGAAAAAATTTATCCAGTCATTGAAGCTGGCGCCAAAGGCTATATGCTTAA
AACGAGCAGTGCAGCAGAGATTCTAAATAGTATCCGTAAGGTTTACCGTGGAGAGGAAGCTATCGAAACTGAGGTAGACA
ATAAGATTAAATACCACGATAGTCACCCGAACTTACATGATGACTTGACCGCGCGCGAACGTGATATCTTAGCCCTCCTA
GCTAAAGGATATGACAATCAAACCATTGCTAACGAACTTTTTATTTCTTTAAAAACCGTCAAGACTCATGTGTCTAATAT
CCTTGGGAAATTAAATGTTGATGACCGTACTCAGGCTGTAGTTTATGCCTTTAGACATCATCTGGTTTCACAGGATGATG
AATAA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(7-118)

Bacterial regulatory proteins, luxR family (GerE)

(149-203)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

50.485

96.262

0.486
  degU Bacillus subtilis subsp. subtilis str. 168

36.161

100

0.379