Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   J7T92_RS06230 Genome accession   NZ_CP072429
Coordinates   1181752..1183539 (-) Length   595 a.a.
NCBI ID   WP_372588865.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain S24747     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 1176752..1188539
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J7T92_RS06205 (J7T92_06190) - 1177112..1178188 (-) 1077 WP_011681318.1 aspartate-semialdehyde dehydrogenase -
  J7T92_RS06210 (J7T92_06195) - 1178549..1179061 (-) 513 WP_002951148.1 GNAT family N-acetyltransferase -
  J7T92_RS06215 - 1179220..1179357 (+) 138 WP_372588866.1 hypothetical protein -
  J7T92_RS06220 (J7T92_06200) - 1179339..1180022 (+) 684 Protein_1171 ISL3 family transposase -
  J7T92_RS06225 (J7T92_06205) cls 1180113..1181663 (-) 1551 WP_372588901.1 cardiolipin synthase -
  J7T92_RS06230 (J7T92_06210) uvrC 1181752..1183539 (-) 1788 WP_372588865.1 excinuclease ABC subunit UvrC Machinery gene
  J7T92_RS06235 (J7T92_06215) - 1183599..1184294 (-) 696 WP_011681324.1 YjjG family noncanonical pyrimidine nucleotidase -
  J7T92_RS06240 (J7T92_06220) sdaAB 1184572..1185243 (+) 672 WP_011681325.1 L-serine ammonia-lyase, iron-sulfur-dependent subunit beta -
  J7T92_RS06245 (J7T92_06225) sdaAA 1185256..1186125 (+) 870 WP_011226205.1 L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha -
  J7T92_RS06250 - 1186309..1186541 (+) 233 Protein_1177 IS30 family transposase -
  J7T92_RS06255 (J7T92_06230) - 1186848..1187417 (-) 570 WP_014727594.1 hypothetical protein -
  J7T92_RS06260 (J7T92_06235) - 1187560..1188344 (-) 785 Protein_1179 ABC transporter permease -

Sequence

Protein


Download         Length: 595 a.a.        Molecular weight: 68557.92 Da        Isoelectric Point: 9.4695

>NTDB_id=482283 J7T92_RS06230 WP_372588865.1 1181752..1183539(-) (uvrC) [Streptococcus thermophilus strain S24747]
MNGLIKHKLELLPSNPGCYLHKDKFGNIIYVGKAKNLKNRVRSYFRGSHDTKTELLVSEIADFEFIVTESNIEALLLEIN
LIQENMPKFNIRLKDDKSYPFIKITKELYPRLLITRQVKKDGGLYFGPYPDSGAANEIKKLLDRIFPFKKCKNPANKVCF
YYHIGQCNAHTICHTTEDYWQGLVEDVKNFLNGHDDKIVNQLKAKMKDMSDQMAFERAAEYRDLIEAVSTLRTKQRVIRQ
DMQDRDIFGYYVDKGWMCVQVFFVRQGKLIQRDVNMFPYYNDAEEDFLTYMGQFYLDSRHLKPREIFIPGDIDQESVEAL
VGDEVKVFKPQRGEKKQLVNLATKNARVSLTQKFDLLEKDIAKTQGAIENLGKLMGIPTPVRIESFDNSNIMGTSPVSAM
VVFENGKPNKKEYRKYKIKTVEGPDDYASMREVIRRRYSRVKRDGLTPPDLIIMDGGQGQVNVAKDVLRNELNLSIPVAG
LQKNDKHQTNELLFGDPLRVIDLPRQSEEFFLLHRIQDEVHRFAITFHRQVRSKNSFSSKLDGVEGLGPKRKQKLLKNFK
SMTAIQQASVEDIQALGIPEKVAQALLDKLSQDSH

Nucleotide


Download         Length: 1788 bp        

>NTDB_id=482283 J7T92_RS06230 WP_372588865.1 1181752..1183539(-) (uvrC) [Streptococcus thermophilus strain S24747]
ATGAATGGTCTGATTAAACATAAGTTGGAACTGCTCCCAAGCAACCCAGGGTGTTATCTCCACAAGGACAAATTCGGCAA
TATTATTTATGTCGGTAAGGCTAAAAATCTAAAAAATCGTGTGCGTAGCTATTTTCGTGGAAGCCATGATACCAAGACGG
AGCTTTTGGTATCTGAGATTGCAGACTTTGAATTTATCGTAACCGAGTCTAATATCGAGGCCCTGCTTTTGGAAATTAAC
CTCATTCAAGAGAATATGCCCAAATTTAATATTCGCCTCAAGGATGATAAATCTTACCCTTTTATCAAGATTACCAAGGA
GCTCTATCCAAGGCTCTTGATTACTCGCCAGGTCAAAAAGGATGGTGGTCTTTATTTCGGCCCTTACCCAGACTCTGGTG
CAGCCAATGAAATCAAGAAGCTTTTGGACCGTATTTTCCCCTTTAAGAAATGTAAAAATCCTGCCAACAAGGTTTGTTTT
TATTACCATATTGGTCAATGTAATGCCCACACCATCTGTCACACCACTGAGGATTATTGGCAAGGTTTGGTTGAGGATGT
CAAGAATTTCCTAAACGGTCATGATGATAAAATCGTTAACCAGCTCAAGGCCAAGATGAAGGACATGTCTGACCAGATGG
CGTTTGAGCGTGCAGCGGAGTATCGCGATTTGATTGAGGCGGTATCGACACTGAGGACCAAGCAAAGGGTTATCCGTCAG
GACATGCAGGACCGTGATATCTTCGGTTACTACGTGGACAAGGGTTGGATGTGTGTTCAAGTTTTCTTTGTTCGCCAAGG
GAAACTCATCCAGCGTGATGTCAATATGTTCCCTTACTATAATGATGCTGAGGAAGATTTTCTGACCTATATGGGTCAAT
TTTACCTGGATAGTCGTCATCTTAAGCCTAGGGAAATTTTTATTCCTGGAGACATTGATCAAGAGTCTGTCGAAGCTCTG
GTCGGAGATGAAGTCAAGGTTTTTAAACCGCAAAGAGGCGAGAAAAAGCAGTTGGTTAATCTGGCAACGAAAAATGCCCG
TGTCAGCCTGACTCAAAAATTTGATCTTCTTGAAAAAGATATAGCCAAGACCCAAGGAGCCATTGAAAATCTAGGCAAAC
TCATGGGAATTCCGACACCGGTTCGCATCGAGTCCTTCGATAACTCTAACATCATGGGAACGAGCCCTGTATCTGCCATG
GTCGTTTTTGAGAACGGCAAACCTAATAAAAAAGAGTACCGCAAATACAAGATTAAGACGGTTGAAGGGCCTGACGATTA
TGCCAGCATGCGTGAGGTCATTCGTCGCCGTTATAGTCGTGTCAAACGTGATGGTCTAACCCCACCAGACCTCATTATCA
TGGATGGTGGTCAAGGTCAGGTCAATGTCGCTAAGGATGTGCTTCGTAATGAGCTGAATCTATCTATTCCGGTTGCAGGT
CTTCAGAAAAATGACAAGCACCAAACCAATGAATTGCTCTTTGGAGATCCTTTGCGAGTCATTGATTTGCCACGTCAATC
CGAGGAATTTTTCCTCCTTCACCGTATTCAGGATGAAGTACACCGCTTTGCCATCACCTTCCATCGTCAAGTCCGTAGTA
AGAATAGTTTCAGTTCCAAACTTGATGGCGTGGAGGGGTTGGGACCTAAACGCAAACAAAAACTCCTCAAAAACTTCAAA
TCAATGACGGCTATCCAACAAGCCAGTGTCGAAGACATCCAAGCTCTTGGAATTCCTGAAAAAGTAGCTCAAGCTTTATT
AGATAAGTTGAGCCAAGATAGTCATTAA

Domains

Predicted by InterProScan.

GIY-YIG catalytic domain (GIY-YIG)

(16-87)

Helix-hairpin-helix domain (HHH_5)

(540-590)

UvrB/uvrC motif (UVR)

(196-229)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(375-525)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

76.142

99.328

0.756
  uvrC Streptococcus pneumoniae R6

75.804

99.328

0.753
  uvrC Streptococcus pneumoniae D39

75.804

99.328

0.753