Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   J7U22_RS02835 Genome accession   NZ_CP072428
Coordinates   548761..550548 (+) Length   595 a.a.
NCBI ID   WP_372588865.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain S24749     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 543761..555548
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J7U22_RS02805 (J7U22_02815) - 543956..544740 (+) 785 Protein_529 ABC transporter permease -
  J7U22_RS02810 (J7U22_02820) - 544883..545452 (+) 570 WP_014727594.1 hypothetical protein -
  J7U22_RS02815 - 545759..545991 (-) 233 Protein_531 IS30 family transposase -
  J7U22_RS02820 (J7U22_02825) sdaAA 546175..547044 (-) 870 WP_011226205.1 L-serine ammonia-lyase, iron-sulfur-dependent, subunit alpha -
  J7U22_RS02825 (J7U22_02830) sdaAB 547057..547728 (-) 672 WP_011681325.1 L-serine ammonia-lyase, iron-sulfur-dependent subunit beta -
  J7U22_RS02830 (J7U22_02835) - 548006..548701 (+) 696 WP_011681324.1 YjjG family noncanonical pyrimidine nucleotidase -
  J7U22_RS02835 (J7U22_02840) uvrC 548761..550548 (+) 1788 WP_372588865.1 excinuclease ABC subunit UvrC Machinery gene
  J7U22_RS02840 (J7U22_02845) cls 550637..552187 (+) 1551 WP_372588901.1 cardiolipin synthase -
  J7U22_RS02845 (J7U22_02850) - 552278..552961 (-) 684 Protein_537 ISL3 family transposase -
  J7U22_RS02850 - 552943..553080 (-) 138 WP_372588866.1 hypothetical protein -
  J7U22_RS02855 (J7U22_02855) - 553239..553751 (+) 513 WP_002951148.1 GNAT family N-acetyltransferase -
  J7U22_RS02860 (J7U22_02860) - 554112..555188 (+) 1077 WP_011681318.1 aspartate-semialdehyde dehydrogenase -

Sequence

Protein


Download         Length: 595 a.a.        Molecular weight: 68557.92 Da        Isoelectric Point: 9.4695

>NTDB_id=482164 J7U22_RS02835 WP_372588865.1 548761..550548(+) (uvrC) [Streptococcus thermophilus strain S24749]
MNGLIKHKLELLPSNPGCYLHKDKFGNIIYVGKAKNLKNRVRSYFRGSHDTKTELLVSEIADFEFIVTESNIEALLLEIN
LIQENMPKFNIRLKDDKSYPFIKITKELYPRLLITRQVKKDGGLYFGPYPDSGAANEIKKLLDRIFPFKKCKNPANKVCF
YYHIGQCNAHTICHTTEDYWQGLVEDVKNFLNGHDDKIVNQLKAKMKDMSDQMAFERAAEYRDLIEAVSTLRTKQRVIRQ
DMQDRDIFGYYVDKGWMCVQVFFVRQGKLIQRDVNMFPYYNDAEEDFLTYMGQFYLDSRHLKPREIFIPGDIDQESVEAL
VGDEVKVFKPQRGEKKQLVNLATKNARVSLTQKFDLLEKDIAKTQGAIENLGKLMGIPTPVRIESFDNSNIMGTSPVSAM
VVFENGKPNKKEYRKYKIKTVEGPDDYASMREVIRRRYSRVKRDGLTPPDLIIMDGGQGQVNVAKDVLRNELNLSIPVAG
LQKNDKHQTNELLFGDPLRVIDLPRQSEEFFLLHRIQDEVHRFAITFHRQVRSKNSFSSKLDGVEGLGPKRKQKLLKNFK
SMTAIQQASVEDIQALGIPEKVAQALLDKLSQDSH

Nucleotide


Download         Length: 1788 bp        

>NTDB_id=482164 J7U22_RS02835 WP_372588865.1 548761..550548(+) (uvrC) [Streptococcus thermophilus strain S24749]
ATGAATGGTCTGATTAAACATAAGTTGGAACTGCTCCCAAGCAACCCAGGGTGTTATCTCCACAAGGACAAATTCGGCAA
TATTATTTATGTCGGTAAGGCTAAAAATCTAAAAAATCGTGTGCGTAGCTATTTTCGTGGAAGCCATGATACCAAGACGG
AGCTTTTGGTATCTGAGATTGCAGACTTTGAATTTATCGTAACCGAGTCTAATATCGAGGCCCTGCTTTTGGAAATTAAC
CTCATTCAAGAGAATATGCCCAAATTTAATATTCGCCTCAAGGATGATAAATCTTACCCTTTTATCAAGATTACCAAGGA
GCTCTATCCAAGGCTCTTGATTACTCGCCAGGTCAAAAAGGATGGTGGTCTTTATTTCGGCCCTTACCCAGACTCTGGTG
CAGCCAATGAAATCAAGAAGCTTTTGGACCGTATTTTCCCCTTTAAGAAATGTAAAAATCCTGCCAACAAGGTTTGTTTT
TATTACCATATTGGTCAATGTAATGCCCACACCATCTGTCACACCACTGAGGATTATTGGCAAGGTTTGGTTGAGGATGT
CAAGAATTTCCTAAACGGTCATGATGATAAAATCGTTAACCAGCTCAAGGCCAAGATGAAGGACATGTCTGACCAGATGG
CGTTTGAGCGTGCAGCGGAGTATCGCGATTTGATTGAGGCGGTATCGACACTGAGGACCAAGCAAAGGGTTATCCGTCAG
GACATGCAGGACCGTGATATCTTCGGTTACTACGTGGACAAGGGTTGGATGTGTGTTCAAGTTTTCTTTGTTCGCCAAGG
GAAACTCATCCAGCGTGATGTCAATATGTTCCCTTACTATAATGATGCTGAGGAAGATTTTCTGACCTATATGGGTCAAT
TTTACCTGGATAGTCGTCATCTTAAGCCTAGGGAAATTTTTATTCCTGGAGACATTGATCAAGAGTCTGTCGAAGCTCTG
GTCGGAGATGAAGTCAAGGTTTTTAAACCGCAAAGAGGCGAGAAAAAGCAGTTGGTTAATCTGGCAACGAAAAATGCCCG
TGTCAGCCTGACTCAAAAATTTGATCTTCTTGAAAAAGATATAGCCAAGACCCAAGGAGCCATTGAAAATCTAGGCAAAC
TCATGGGAATTCCGACACCGGTTCGCATCGAGTCCTTCGATAACTCTAACATCATGGGAACGAGCCCTGTATCTGCCATG
GTCGTTTTTGAGAACGGCAAACCTAATAAAAAAGAGTACCGCAAATACAAGATTAAGACGGTTGAAGGGCCTGACGATTA
TGCCAGCATGCGTGAGGTCATTCGTCGCCGTTATAGTCGTGTCAAACGTGATGGTCTAACCCCACCAGACCTCATTATCA
TGGATGGTGGTCAAGGTCAGGTCAATGTCGCTAAGGATGTGCTTCGTAATGAGCTGAATCTATCTATTCCGGTTGCAGGT
CTTCAGAAAAATGACAAGCACCAAACCAATGAATTGCTCTTTGGAGATCCTTTGCGAGTCATTGATTTGCCACGTCAATC
CGAGGAATTTTTCCTCCTTCACCGTATTCAGGATGAAGTACACCGCTTTGCCATCACCTTCCATCGTCAAGTCCGTAGTA
AGAATAGTTTCAGTTCCAAACTTGATGGCGTGGAGGGGTTGGGACCTAAACGCAAACAAAAACTCCTCAAAAACTTCAAA
TCAATGACGGCTATCCAACAAGCCAGTGTCGAAGACATCCAAGCTCTTGGAATTCCTGAAAAAGTAGCTCAAGCTTTATT
AGATAAGTTGAGCCAAGATAGTCATTAA

Domains

Predicted by InterProScan.

GIY-YIG catalytic domain (GIY-YIG)

(16-87)

Helix-hairpin-helix domain (HHH_5)

(540-590)

UvrB/uvrC motif (UVR)

(196-229)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(375-525)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

76.142

99.328

0.756
  uvrC Streptococcus pneumoniae R6

75.804

99.328

0.753
  uvrC Streptococcus pneumoniae D39

75.804

99.328

0.753