Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   J7U22_RS02290 Genome accession   NZ_CP072428
Coordinates   444608..445252 (+) Length   214 a.a.
NCBI ID   WP_207559816.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain S24749     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 439608..450252
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J7U22_RS02270 (J7U22_02270) stkP/pknB 439983..441854 (+) 1872 WP_372429233.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  J7U22_RS02275 - 442491..442658 (+) 168 WP_014608530.1 potassium channel family protein -
  J7U22_RS02280 (J7U22_02280) liaF 442913..443611 (+) 699 WP_011226289.1 cell wall-active antibiotics response protein LiaF -
  J7U22_RS02285 (J7U22_02285) - 443608..444618 (+) 1011 WP_180479473.1 sensor histidine kinase -
  J7U22_RS02290 (J7U22_02290) vraR 444608..445252 (+) 645 WP_207559816.1 response regulator transcription factor Regulator
  J7U22_RS02305 (J7U22_02305) rimM 445923..446441 (+) 519 WP_011226286.1 ribosome maturation factor RimM -
  J7U22_RS02310 (J7U22_02310) trmD 446431..447150 (+) 720 WP_011226285.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  J7U22_RS02315 (J7U22_02315) - 447152..448150 (+) 999 WP_014608529.1 NAD(P)/FAD-dependent oxidoreductase -

Sequence

Protein


Download         Length: 214 a.a.        Molecular weight: 24074.42 Da        Isoelectric Point: 4.5222

>NTDB_id=482162 J7U22_RS02290 WP_207559816.1 444608..445252(+) (vraR) [Streptococcus thermophilus strain S24749]
MSNKINVILVDDHEMVRLGLKSFLNLQGDVEVVGEAENGREGVDLALELRPDVVVMDLVMPELDGVQATLELLKEWPEAK
ILVLTSYLDNEKIYPVIEAGAKGYMLKTSSAAEILNSIRKVYRGEEAIETEVDNKIKYHDSYPNLHDDLTARERDILALL
AKGYDNQTIANELFISLKTVKTHVSNILGKLNVDDRTQAVVYAFRHHLVSQDDE

Nucleotide


Download         Length: 645 bp        

>NTDB_id=482162 J7U22_RS02290 WP_207559816.1 444608..445252(+) (vraR) [Streptococcus thermophilus strain S24749]
ATGTCGAATAAGATTAATGTAATTTTGGTAGATGACCATGAAATGGTTCGTTTAGGCCTTAAGAGTTTCTTGAATCTCCA
AGGAGATGTAGAAGTGGTTGGAGAGGCAGAAAACGGCCGTGAGGGTGTCGATCTTGCCCTGGAGCTACGACCAGATGTCG
TTGTTATGGACCTTGTTATGCCTGAGCTAGATGGTGTTCAGGCGACTTTGGAATTGCTCAAAGAATGGCCTGAAGCTAAG
ATTCTAGTTTTGACCAGCTATTTGGATAATGAAAAAATTTATCCAGTCATTGAAGCTGGCGCCAAAGGCTATATGCTTAA
AACGAGCAGTGCAGCAGAGATTCTAAATAGTATCCGTAAGGTTTACCGTGGAGAGGAAGCTATCGAAACTGAGGTAGACA
ATAAGATTAAATACCACGATAGTTACCCGAACTTACATGATGACTTGACCGCGCGCGAACGTGATATCTTAGCCCTCCTA
GCTAAAGGCTATGACAATCAAACCATTGCTAACGAACTTTTTATTTCTTTAAAAACCGTCAAGACTCATGTGTCTAATAT
CCTTGGGAAATTAAATGTTGATGACCGTACTCAGGCTGTAGTTTATGCCTTTAGACATCATCTGGTTTCACAGGATGATG
AATAA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-203)

Response regulator receiver domain (Response_reg)

(7-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

50.485

96.262

0.486
  degU Bacillus subtilis subsp. subtilis str. 168

36.818

100

0.379