Detailed information NTG0048210

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: SPN034183_RS09595
• Genome accession: NC_021028
• Coordinates: 1774768..1775667 (-)
• Length: 299 a.a.
• NCBI ID: WP_000904867.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae SPN034183
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1769768..1780667

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPN034183_RS09570 (SPN034183_17470)	rsmA	1770098..1770970 (-)	873	WP_001216830.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
SPN034183_RS09575 (SPN034183_17480)	-	1771101..1771409 (-)	309	WP_000333257.1	hypothetical protein	-
SPN034183_RS09580 (SPN034183_17490)	-	1771402..1772043 (-)	642	WP_000565531.1	ABC transporter ATP-binding protein	-
SPN034183_RS09585 (SPN034183_17500)	-	1772045..1774075 (-)	2031	WP_000825263.1	bacteriocin-associated integral membrane family protein	-
SPN034183_RS09590 (SPN034183_17510)	-	1774152..1774448 (-)	297	WP_000815394.1	lactococcin 972 family bacteriocin	-
SPN034183_RS09595 (SPN034183_17520)	comR	1774768..1775667 (-)	900	WP_000904867.1	helix-turn-helix domain-containing protein	Regulator
SPN034183_RS09600 (SPN034183_17530)	rnmV	1775739..1776299 (-)	561	WP_000664448.1	ribonuclease M5	-
SPN034183_RS09605 (SPN034183_17540)	-	1776299..1777072 (-)	774	WP_000575607.1	TatD family hydrolase	-
SPN034183_RS09610 (SPN034183_17550)	-	1777378..1778055 (-)	678	WP_219338615.1	DUF1542 domain-containing protein	-
SPN034183_RS09615 (SPN034183_17560)	rpmH	1778294..1778428 (-)	135	WP_000831906.1	50S ribosomal protein L34	-
SPN034183_RS09620 (SPN034183_17570)	-	1778573..1779787 (-)	1215	WP_000666469.1	pyridoxal phosphate-dependent aminotransferase	-
SPN034183_RS09625 (SPN034183_17580)	-	1779943..1780236 (-)	294	WP_000977365.1	hypothetical protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35191.04 Da
• Isoelectric Point: 5.0703

>NTDB_id=48210 SPN034183_RS09595 WP_000904867.1 1774768..1775667(-) (comR) [Streptococcus pneumoniae SPN034183]
MLIGQKIKEIRIEKGISRPDFCGDEQGLTVRQLSRIESGASQPSLPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQI
LREPIYGKEEEYDKKEACLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAKLIGDGFLVKKLTEEWQEDVKKYL

Nucleotide

• Length: 900 bp

>NTDB_id=48210 SPN034183_RS09595 WP_000904867.1 1774768..1775667(-) (comR) [Streptococcus pneumoniae SPN034183]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGG
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGCCTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTTCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGCCTCAGATTATAGAAAAAGAAGCTTATTCAATAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTCTT
TCTTTTGGAACAGAAGAAGGTAACTCAAATAGAGAATTACTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCTTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGTAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGAAGCTAATTGGAGATGGATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (7-59)

• ComR tetratricopeptide (ComR_TPR) (70-291)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	37.755	98.328	0.371
comR	Streptococcus suis P1/7	37.801	97.324	0.368
comR	Streptococcus suis 05ZYH33	37.801	97.324	0.368