Detailed information    

insolico Bioinformatically predicted

Overview


Name   comS   Type   Regulator
Locus tag   IB936_RS09435 Genome accession   NZ_CP061133
Coordinates   49344..49439 (+) Length   31 a.a.
NCBI ID   WP_198462994.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain BSAC_bs472 isolate Invasive disease     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context


Location: 44344..54439
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IB936_RS00260 (IB936_00260) - 45532..46416 (+) 885 WP_011528141.1 HNH endonuclease -
  IB936_RS00265 (IB936_00265) purB 46925..48217 (+) 1293 WP_011528142.1 adenylosuccinate lyase -
  IB936_RS00270 (IB936_00270) comR 48349..49260 (+) 912 WP_011528143.1 transcriptional regulator Rgg4/ComR Regulator
  IB936_RS09435 comS 49344..49439 (+) 96 WP_198462994.1 quorum-sensing system DWW-type pheromone Regulator
  IB936_RS00275 (IB936_00275) ruvB 49486..50484 (+) 999 WP_002986679.1 Holliday junction branch migration DNA helicase RuvB -
  IB936_RS00280 (IB936_00280) - 50622..51059 (+) 438 WP_002987727.1 low molecular weight protein-tyrosine-phosphatase -
  IB936_RS00285 (IB936_00285) - 51083..51484 (+) 402 WP_002986671.1 MORN repeat-containing protein -
  IB936_RS00290 (IB936_00290) - 51481..53256 (+) 1776 WP_011528145.1 acyltransferase family protein -

Sequence


Protein


Download         Length: 31 a.a.        Molecular weight: 3857.66 Da        Isoelectric Point: 10.0436

>NTDB_id=480955 IB936_RS09435 WP_198462994.1 49344..49439(+) (comS) [Streptococcus pyogenes strain BSAC_bs472 isolate Invasive disease]
MLKKYKYYFIFAALLSFKVVQELSAVDWWRL

Nucleotide


Download         Length: 96 bp        

>NTDB_id=480955 IB936_RS09435 WP_198462994.1 49344..49439(+) (comS) [Streptococcus pyogenes strain BSAC_bs472 isolate Invasive disease]
ATGTTAAAAAAGTATAAGTACTATTTTATATTCGCAGCTCTACTATCTTTTAAAGTAGTTCAAGAGCTTAGTGCTGTTGA
CTGGTGGCGATTATAA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comS Streptococcus pyogenes MGAS8232

100

100

1

  comS Streptococcus pyogenes MGAS315

45.161

100

0.452