Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   J5Z97_RS06105 Genome accession   NZ_CP072112
Coordinates   1194557..1195219 (-) Length   220 a.a.
NCBI ID   WP_002995626.1    Uniprot ID   A0A0H2UV22
Organism   Streptococcus pyogenes strain M08500     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1189557..1200219
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J5Z97_RS06085 (J5Z97_06085) - 1190126..1190353 (-) 228 WP_011054657.1 hypothetical protein -
  J5Z97_RS06090 (J5Z97_06090) sodA 1190520..1191125 (-) 606 WP_023611693.1 superoxide dismutase SodA -
  J5Z97_RS06095 (J5Z97_06095) holA 1191222..1192262 (-) 1041 WP_023611671.1 DNA polymerase III subunit delta -
  J5Z97_RS06100 (J5Z97_06100) comEC/celB 1192333..1194576 (-) 2244 WP_208769249.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  J5Z97_RS06105 (J5Z97_06105) comEA/celA/cilE 1194557..1195219 (-) 663 WP_002995626.1 ComEA family DNA-binding protein Machinery gene
  J5Z97_RS06110 (J5Z97_06110) - 1195419..1196159 (-) 741 WP_012560804.1 1-acyl-sn-glycerol-3-phosphate acyltransferase -
  J5Z97_RS06115 (J5Z97_06115) - 1196277..1197053 (+) 777 WP_023611675.1 tRNA1(Val) (adenine(37)-N6)-methyltransferase -
  J5Z97_RS06120 (J5Z97_06120) - 1197043..1197321 (+) 279 WP_002989164.1 GIY-YIG nuclease family protein -
  J5Z97_RS06125 (J5Z97_06125) - 1197345..1199345 (-) 2001 WP_023611672.1 potassium transporter Kup -

Sequence

Protein


Download         Length: 220 a.a.        Molecular weight: 24623.45 Da        Isoelectric Point: 6.7451

>NTDB_id=480555 J5Z97_RS06105 WP_002995626.1 1194557..1195219(-) (comEA/celA/cilE) [Streptococcus pyogenes strain M08500]
MLDELLIKGKSFLRERYFLPYLISLLLGLFLILSFSFLFWGNRQSKAAVPALREISPVKQQVSEEKKEIQEDNSILVDLK
GAVQKEGVYKLTASSRVRDVIELAGGLTSEADKHAINFAEKLTDEQVVYVPKQGEEISVLPRSLVSGKKETASKDQSKVH
INKASLEELQHIPGIGAKRAQDIIDMRDKLGGFKALEDLRQVSGIGEKTLEKLKDDIFLD

Nucleotide


Download         Length: 663 bp        

>NTDB_id=480555 J5Z97_RS06105 WP_002995626.1 1194557..1195219(-) (comEA/celA/cilE) [Streptococcus pyogenes strain M08500]
ATGTTAGACGAATTATTAATTAAAGGAAAATCGTTTTTGAGAGAGCGGTATTTTCTGCCATACCTAATTAGTCTTTTATT
AGGACTTTTTCTAATACTAAGCTTCAGTTTTTTGTTCTGGGGAAATAGGCAGAGCAAGGCAGCCGTTCCTGCTTTGAGAG
AAATATCGCCTGTGAAACAGCAGGTTAGTGAAGAAAAAAAGGAAATTCAAGAAGATAACAGTATTTTAGTGGATTTAAAA
GGCGCCGTACAAAAAGAGGGAGTTTATAAGCTAACTGCTAGCAGTCGTGTGCGAGATGTCATTGAACTAGCTGGAGGCCT
AACTTCAGAAGCTGATAAACATGCTATTAATTTTGCAGAAAAACTAACTGATGAGCAAGTTGTTTATGTACCTAAACAAG
GAGAAGAGATTTCTGTGCTACCAAGGTCATTAGTTTCTGGTAAAAAAGAAACTGCCAGCAAGGATCAGTCAAAGGTTCAT
ATTAATAAGGCCAGCTTAGAAGAACTACAACATATCCCAGGTATTGGTGCTAAAAGAGCTCAGGATATTATTGATATGAG
AGATAAGTTAGGTGGTTTTAAAGCGTTAGAAGATCTCCGTCAGGTTTCGGGGATTGGCGAAAAAACGCTCGAGAAATTAA
AAGATGACATTTTCTTGGACTAA

Domains

Predicted by InterProScan.

SLBB domain (SLBB)

(77-130)

Helix-hairpin-helix motif (HHH_3)

(156-217)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H2UV22

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

42.995

94.091

0.405