Detailed information NTG0048035

Bioinformatically predicted

Overview

• Name: pilA
• Type: Machinery gene
• Locus tag: NMBH4476_RS00235
• Genome accession: NC_017516
• Coordinates: 43138..44403 (+)
• Length: 421 a.a.
• NCBI ID: WP_002243928.1
• Uniprot ID: P57011
• Organism: Neisseria meningitidis H44/76
• Function: assembly of type IV pilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 38138..49403

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NMBH4476_RS00215 (NMBH4476_0040)	-	38868..39869 (+)	1002	WP_002243927.1	thiamine ABC transporter substrate-binding protein	-
NMBH4476_RS00220 (NMBH4476_0041)	-	39963..40811 (+)	849	WP_002215243.1	mechanosensitive ion channel family protein	-
NMBH4476_RS00225 (NMBH4476_0042)	-	40837..41322 (+)	486	WP_002215245.1	CinA family protein	-
NMBH4476_RS00230 (NMBH4476_0043)	msrAB	41424..42992 (-)	1569	WP_002221795.1	bifunctional peptide-methionine (S)-S-oxide reductase MsrA/peptide-methionine (R)-S-oxide reductase MsrB	-
NMBH4476_RS00235 (NMBH4476_0044)	pilA	43138..44403 (+)	1266	WP_002243928.1	signal recognition particle-docking protein FtsY	Machinery gene
NMBH4476_RS00245 (NMBH4476_0045)	-	45031..45315 (+)	285	WP_002216166.1	GIY-YIG nuclease family protein	-
NMBH4476_RS15760	pilC	48075..48200 (+)	126	WP_009344866.1	hypothetical protein	Machinery gene

Sequence

Protein

• Length: 421 a.a.
• Molecular weight: 45143.47 Da
• Isoelectric Point: 4.5557

>NTDB_id=48035 NMBH4476_RS00235 WP_002243928.1 43138..44403(+) (pilA) [Neisseria meningitidis H44/76]
MFSFFRRKKKQETPALEEAQIQETAAKAESELAQIVENIKEDAESLAESVKGQVESAVETVSGAVEQVKETVAEMLSEAE
EAAEKAAEQVEAAKEAVAETVGEAVGQVQEAVATTEEHKLGWAARLKQGLTKSRDKMAKSLAGVFGGGQIDEDLYEELET
VLITSDMGMEATEYLMKDVRDRVSLKGLKDGNELRGALKEALYDLIKPLEKPLVLPETKEPFVIMLAGINGAGKTTSIGK
LAKYFQAQGKSVLLAAGDTFRAAAREQLQAWGERNNVTVISQTTGDSAAVCFDAVQAAKARGIDIVLADTAGRLPTQLHL
MEEIKKVKRVLQKAMPDAPHEIIVVLDANIGQNAVNQVKAFDDALGLTGLIVTKLDGTAKGGILAALASDRPVPVRYIGV
GEGIDDLRPFDARAFVDALLD

Nucleotide

• Length: 1266 bp

>NTDB_id=48035 NMBH4476_RS00235 WP_002243928.1 43138..44403(+) (pilA) [Neisseria meningitidis H44/76]
ATGTTCAGCTTCTTCCGTCGCAAGAAAAAACAGGAAACGCCGGCTCTCGAGGAGGCTCAAATTCAGGAAACCGCAGCAAA
AGCAGAATCTGAACTTGCTCAAATAGTTGAAAATATTAAAGAAGATGCTGAATCTTTAGCAGAAAGCGTCAAAGGGCAGG
TCGAATCTGCCGTTGAAACCGTCAGCGGTGCGGTTGAACAGGTAAAGGAAACCGTTGCCGAGATGCTGTCTGAAGCAGAG
GAAGCGGCGGAAAAAGCAGCGGAACAAGTCGAAGCGGCAAAAGAAGCCGTTGCCGAAACCGTCGGCGAGGCTGTCGGGCA
AGTTCAAGAAGCCGTTGCGACAACTGAAGAACACAAGCTCGGTTGGGCGGCGCGTTTGAAACAAGGCCTGACCAAATCGC
GCGACAAAATGGCGAAATCGCTGGCGGGCGTGTTCGGCGGCGGACAAATCGACGAAGATTTATACGAAGAGCTGGAAACC
GTGCTGATTACCAGCGATATGGGCATGGAAGCCACCGAATACCTGATGAAAGACGTGCGCGACCGCGTCAGCCTCAAAGG
GCTGAAAGACGGCAACGAATTGCGCGGCGCGTTGAAAGAAGCCTTGTACGACCTGATTAAGCCTCTGGAGAAACCTTTGG
TTTTGCCCGAAACCAAAGAGCCGTTTGTCATCATGCTTGCCGGCATCAACGGCGCGGGCAAAACCACGTCTATCGGTAAA
CTCGCCAAATATTTCCAAGCGCAGGGCAAATCCGTATTGCTGGCGGCAGGCGATACTTTCCGTGCCGCCGCGCGTGAGCA
GCTTCAAGCTTGGGGCGAGCGCAACAACGTAACCGTGATTTCGCAAACCACGGGCGATTCCGCCGCCGTGTGCTTCGATG
CCGTCCAAGCCGCCAAAGCGCGCGGCATCGACATTGTGCTGGCCGACACCGCCGGCCGCCTGCCCACGCAGCTTCATTTG
ATGGAAGAAATCAAAAAAGTGAAACGCGTGCTGCAAAAAGCCATGCCCGACGCGCCGCACGAAATCATCGTCGTGCTTGA
TGCCAATATCGGGCAAAACGCCGTCAACCAAGTCAAAGCCTTTGACGACGCATTGGGGCTGACCGGTTTAATCGTTACCA
AACTCGACGGCACGGCAAAAGGCGGCATCCTCGCCGCGCTTGCCTCCGACCGCCCCGTTCCCGTCCGCTATATCGGCGTG
GGCGAAGGCATAGACGACCTGCGCCCGTTTGACGCGCGCGCGTTTGTGGACGCACTGCTGGATTGA

Domains

Predicted by InterproScan.

• SRP54-type protein, GTPase domain (SRP54) (221-420)

• SRP54-type protein, helical bundle domain (SRP54_N) (136-202)

3D structure

• AlphaFold DB: P57011

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
pilA	Neisseria gonorrhoeae MS11	94.774	100	0.948