Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   IBL27_RS07440 Genome accession   NZ_CP061071
Coordinates   1519350..1520651 (-) Length   433 a.a.
NCBI ID   WP_019806030.1    Uniprot ID   -
Organism   Streptococcus mutans B04Sm5     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1514350..1525651
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IBL27_RS07415 (IBL27_07415) - 1514408..1515043 (+) 636 WP_002300278.1 hypothetical protein -
  IBL27_RS07420 (IBL27_07420) - 1515123..1516823 (-) 1701 WP_002308502.1 zinc ribbon domain-containing protein -
  IBL27_RS07425 (IBL27_07425) - 1516843..1517937 (-) 1095 WP_002308500.1 hypothetical protein -
  IBL27_RS07430 (IBL27_07430) hpf 1518061..1518609 (-) 549 WP_002263024.1 ribosome hibernation-promoting factor, HPF/YfiA family -
  IBL27_RS07435 (IBL27_07435) - 1518688..1519353 (-) 666 WP_024784388.1 ComF family protein -
  IBL27_RS07440 (IBL27_07440) comFA/cflA 1519350..1520651 (-) 1302 WP_019806030.1 DEAD/DEAH box helicase Machinery gene
  IBL27_RS07445 (IBL27_07445) - 1520724..1521353 (+) 630 WP_002267042.1 YigZ family protein -
  IBL27_RS07450 (IBL27_07450) cysK 1521444..1522370 (+) 927 WP_002269524.1 cysteine synthase A -
  IBL27_RS07455 (IBL27_07455) - 1522706..1523797 (-) 1092 WP_002263029.1 glycerol dehydrogenase -
  IBL27_RS07460 (IBL27_07460) - 1523836..1524504 (-) 669 WP_002263030.1 fructose-6-phosphate aldolase -

Sequence

Protein


Download         Length: 433 a.a.        Molecular weight: 49519.64 Da        Isoelectric Point: 9.9705

>NTDB_id=480262 IBL27_RS07440 WP_019806030.1 1519350..1520651(-) (comFA/cflA) [Streptococcus mutans B04Sm5]
MENLENYYGRLLTENQMNSDLKKQAKILPAMIKKPHYFICNRCGSQNNLGNALPDGSIYCRACLVFGRLTNRDSLYYFEQ
KPFPRGQVLRWQGQLTPFQQEVSRGLKKSVCHKENMLIHAVTGAGKTEMIYETLASILNQGGAVALASSRIDVCIELYKR
LSRDFSCPISLLHGESEAYERSPLVIATTHQLLKFYRAFDLLIIDEVDAFPFVDNKMLYYAVDHCLKSDGVKVFLTATST
DQLDKQVKQGKLKKLHLARRFHANPLVVPKPIWLNLSLERLQRDKLPRSFLQQIRIQRQTQFPLLIFFPNIEDGLTFAKS
LQTYLPNEKIDFVSSLTTDRLEKVENFRKGNTQILVSTTILERGVTFPCVDVFVMMSNHYLFTKSSLVQIAGRVGRSADR
PDGKLLFFHNGMNRAMKKAIMEIKTMNKKGGFA

Nucleotide


Download         Length: 1302 bp        

>NTDB_id=480262 IBL27_RS07440 WP_019806030.1 1519350..1520651(-) (comFA/cflA) [Streptococcus mutans B04Sm5]
ATGGAGAATTTAGAGAATTATTATGGCCGCCTCTTGACCGAGAATCAAATGAACAGTGATTTGAAAAAGCAAGCTAAAAT
CTTGCCAGCTATGATAAAAAAACCGCATTACTTTATCTGCAATCGTTGCGGCAGTCAGAACAATCTTGGTAATGCTTTGC
CGGATGGATCTATCTACTGTCGAGCTTGTCTTGTCTTTGGACGTCTTACTAACAGGGACAGTCTTTATTATTTTGAGCAA
AAGCCTTTTCCAAGGGGTCAGGTCTTAAGGTGGCAAGGGCAATTAACCCCTTTTCAGCAGGAAGTTTCCCGTGGTTTAAA
AAAGAGTGTTTGCCATAAGGAAAATATGCTTATTCATGCTGTAACAGGTGCAGGCAAAACGGAGATGATTTATGAGACTC
TGGCCAGCATTCTCAATCAAGGGGGTGCGGTTGCACTTGCTAGTTCTCGCATTGATGTCTGCATAGAACTGTATAAACGT
TTAAGTCGTGACTTTTCTTGTCCTATCAGTCTTTTGCATGGAGAGTCAGAAGCTTATGAACGCAGTCCATTAGTGATTGC
AACCACGCATCAACTTTTGAAATTTTACCGAGCTTTTGATTTGTTAATTATTGATGAAGTAGATGCCTTTCCTTTTGTTG
ACAATAAGATGCTCTATTATGCTGTAGATCATTGTCTGAAATCAGATGGTGTCAAAGTATTTTTGACTGCAACTTCGACT
GACCAATTAGACAAACAGGTTAAGCAAGGGAAGCTAAAAAAACTGCATTTAGCCAGACGATTTCATGCCAATCCCTTAGT
TGTTCCCAAGCCAATTTGGTTGAATTTATCTCTTGAAAGATTACAAAGAGATAAATTACCGCGCTCTTTTTTACAGCAGA
TAAGAATTCAAAGGCAGACTCAATTCCCTCTTTTGATCTTTTTTCCGAATATTGAAGATGGTTTAACCTTTGCTAAATCA
CTGCAAACTTATCTTCCAAATGAGAAAATTGATTTTGTTTCCAGCTTGACAACAGATCGTTTAGAAAAAGTCGAAAATTT
TAGAAAAGGAAACACACAAATTTTGGTTTCAACAACGATTTTAGAGAGGGGAGTCACTTTTCCTTGTGTAGATGTTTTTG
TCATGATGAGCAACCATTATCTGTTCACCAAAAGTTCTCTGGTACAAATTGCTGGTCGTGTGGGACGCTCTGCCGATAGA
CCAGATGGAAAATTACTTTTCTTTCATAATGGAATGAACAGAGCCATGAAAAAGGCCATTATGGAAATCAAGACTATGAA
CAAAAAAGGAGGTTTTGCATGA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(296-397)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

59.251

98.614

0.584
  comFA/cflA Streptococcus pneumoniae D39

59.251

98.614

0.584
  comFA/cflA Streptococcus pneumoniae R6

59.251

98.614

0.584
  comFA/cflA Streptococcus pneumoniae TIGR4

59.251

98.614

0.584
  comFA/cflA Streptococcus mitis NCTC 12261

58.548

98.614

0.577
  comFA/cflA Streptococcus mitis SK321

58.08

98.614

0.573
  comFA Lactococcus lactis subsp. cremoris KW2

51.523

90.993

0.469
  comFA Latilactobacillus sakei subsp. sakei 23K

38.498

98.383

0.379