Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrB   Type   Machinery gene
Locus tag   IAU62_RS10875 Genome accession   NZ_CP061029
Coordinates   2269482..2271110 (+) Length   542 a.a.
NCBI ID   WP_061642462.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain Z0118SE0132     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 2254813..2270811 2269482..2271110 flank -1329


Gene organization within MGE regions


Location: 2254813..2271110
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IAU62_RS10810 mecI 2254813..2255184 (-) 372 WP_000369214.1 mecA-type methicillin resistance repressor MecI -
  IAU62_RS10815 mecR1 2255184..2256941 (-) 1758 WP_000952923.1 beta-lactam sensor/signal transducer MecR1 -
  IAU62_RS10820 mecA 2257038..2259047 (+) 2010 WP_001801873.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -
  IAU62_RS10825 - 2259093..2259521 (-) 429 WP_000872606.1 MaoC family dehydratase -
  IAU62_RS10830 - 2259618..2260361 (-) 744 WP_000958858.1 glycerophosphoryl diester phosphodiesterase -
  IAU62_RS10835 - 2261278..2261667 (-) 390 WP_020444595.1 hydroxymethylglutaryl-CoA synthase -
  IAU62_RS10840 - 2261703..2262377 (+) 675 WP_001106057.1 IS6-like element IS257 family transposase -
  IAU62_RS10845 - 2262424..2262594 (+) 171 WP_155734542.1 hypothetical protein -
  IAU62_RS10850 - 2262627..2263538 (-) 912 WP_046464619.1 ABC transporter substrate-binding protein -
  IAU62_RS10855 - 2264169..2265683 (+) 1515 WP_046464618.1 hypothetical protein -
  IAU62_RS10860 ssb 2265854..2266147 (+) 294 WP_046464617.1 cassette chromosome ssDNA-binding protein -
  IAU62_RS10865 cch1 2266147..2267913 (+) 1767 WP_061544227.1 cassette chromosome replicative helicase -
  IAU62_RS10870 ccrA 2268124..2269485 (+) 1362 WP_061544228.1 cassette chromosome recombinase CcrA Machinery gene
  IAU62_RS10875 ccrB 2269482..2271110 (+) 1629 WP_061642462.1 cassette chromosome recombinase CcrB Machinery gene

Sequence

Protein


Download         Length: 542 a.a.        Molecular weight: 62339.47 Da        Isoelectric Point: 9.5866

>NTDB_id=479880 IAU62_RS10875 WP_061642462.1 2269482..2271110(+) (ccrB) [Staphylococcus epidermidis strain Z0118SE0132]
MTQLKKKRIGLYARVSTEMQTDGYSIHGQLNQLTEYCQFQGYEVVDEYTDRGISGKTTQRPELQRMLKDAKGGKLDGIMV
YNTTRLARNTSDLLNIVEELYEINVEFFSLTEKIEIASSTGKLMLQILASFAEFERNVIVENVFNGQRQRAIEGYYQGNL
PLGYDKVPESKKELMINQHEANIVKYIFESYAKGHGYRKIANTLNHKGYVTKKGKPFSISSITYIISNPFYIGKIQFAKY
RHWSDKRRKGLNEEPIIADGKHAPIIDKALWDKVQFKRQESRKKPQVHGKGTNLLTGIVKCPKCGAAMAASNTTNTLKDG
TKKRIRYYSCSNFRNKGSKVCSANSVRADVLEKYVMDQILEIIKSKKVLKQLVEKVNEQSQIDKSSLNHDIAYKQSQCEE
LKAKMHTLTKTIEDSPDLDSVLKPTILNYQDELNQINNQIHQLEQDKQAEAPHYDADMIANVLQAIFKDIDKLEKSQLKS
LYLTVIDRIDIRNHEHHKKQFYVTLKLNNEIIKQLFNNRPLDEVLLSTSSLFLPQTIYITIE

Nucleotide


Download         Length: 1629 bp        

>NTDB_id=479880 IAU62_RS10875 WP_061642462.1 2269482..2271110(+) (ccrB) [Staphylococcus epidermidis strain Z0118SE0132]
ATGACACAACTCAAAAAGAAACGTATTGGATTATACGCACGTGTATCAACTGAAATGCAAACGGATGGTTACAGTATCCA
TGGTCAATTAAATCAACTTACAGAGTATTGTCAATTTCAAGGTTATGAAGTCGTTGATGAATATACCGATCGTGGTATAT
CAGGTAAAACAACGCAACGTCCTGAACTACAACGTATGTTAAAAGATGCTAAAGGAGGTAAATTAGATGGTATTATGGTA
TATAATACTACTCGTTTAGCTAGAAATACCTCAGATTTATTAAATATTGTCGAAGAATTGTATGAGATTAATGTTGAATT
TTTTAGTCTAACTGAAAAAATAGAAATTGCGAGCTCCACAGGTAAGTTGATGCTCCAAATCTTAGCGAGCTTCGCAGAAT
TTGAAAGAAACGTTATTGTAGAAAACGTGTTTAATGGCCAAAGACAACGTGCTATTGAAGGTTATTACCAAGGTAATTTA
CCTTTAGGCTATGATAAAGTACCTGAGAGTAAAAAAGAGCTTATGATTAATCAACATGAAGCAAATATTGTTAAATATAT
TTTTGAGTCATACGCCAAAGGTCACGGTTATCGTAAGATTGCGAACACATTGAATCATAAAGGTTATGTGACTAAGAAAG
GGAAACCGTTTAGTATTTCGTCCATTACTTATATCATCTCAAACCCTTTTTACATTGGAAAGATACAGTTTGCGAAGTAT
AGACACTGGAGCGATAAAAGACGAAAAGGACTCAATGAGGAACCGATTATCGCAGATGGTAAGCATGCGCCTATTATTGA
TAAAGCTTTATGGGATAAAGTACAGTTTAAACGCCAAGAGAGTCGCAAGAAACCACAAGTTCATGGTAAAGGGACCAATC
TACTTACTGGGATTGTAAAGTGCCCAAAATGTGGCGCAGCCATGGCGGCAAGTAATACGACCAATACATTAAAAGATGGC
ACTAAGAAAAGAATCAGATATTATTCATGTAGCAATTTTAGAAACAAAGGTTCTAAAGTATGTTCAGCCAATAGTGTTAG
AGCAGATGTATTAGAAAAATATGTTATGGACCAGATATTGGAAATTATCAAAAGTAAAAAGGTATTGAAGCAATTGGTTG
AAAAAGTAAATGAACAAAGCCAAATAGATAAATCTTCTTTGAATCATGATATTGCCTATAAACAGTCACAATGTGAAGAA
CTAAAAGCCAAAATGCATACATTAACGAAAACCATTGAAGACTCACCTGACTTAGATAGCGTATTGAAACCAACAATACT
TAACTATCAAGATGAATTGAATCAAATAAATAATCAAATCCATCAACTAGAGCAAGATAAACAAGCAGAAGCTCCACATT
ATGATGCTGATATGATTGCCAACGTACTACAAGCAATATTCAAAGATATAGACAAATTAGAGAAATCTCAGTTGAAATCA
CTCTATCTGACGGTTATCGATCGTATTGATATCCGAAACCATGAACATCATAAGAAGCAATTTTATGTTACGCTTAAACT
GAATAATGAAATTATCAAACAACTATTTAATAACCGTCCACTTGACGAAGTGCTCCTTAGCACTTCGTCTTTATTTTTGC
CACAAACTATATATATAACTATTGAATAA

Domains

Predicted by InterproScan.

Ogr/Delta-like zinc finger (Ogr_Delta)

(300-355)

Resolvase, N terminal domain (Resolvase)

(11-154)

Recombinase (Recombinase)

(179-280)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrB Staphylococcus aureus N315

72.14

100

0.721