Detailed information    

insolico Bioinformatically predicted

Overview

Name   ccrA   Type   Machinery gene
Locus tag   IAU62_RS10870 Genome accession   NZ_CP061029
Coordinates   2268124..2269485 (+) Length   453 a.a.
NCBI ID   WP_061544228.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain Z0118SE0132     
Function   promote SCCmec transfer (predicted from homology)   
Homologous recombination

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
SCCmec 2254813..2270811 2268124..2269485 within 0


Gene organization within MGE regions


Location: 2254813..2270811
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IAU62_RS10810 mecI 2254813..2255184 (-) 372 WP_000369214.1 mecA-type methicillin resistance repressor MecI -
  IAU62_RS10815 mecR1 2255184..2256941 (-) 1758 WP_000952923.1 beta-lactam sensor/signal transducer MecR1 -
  IAU62_RS10820 mecA 2257038..2259047 (+) 2010 WP_001801873.1 PBP2a family beta-lactam-resistant peptidoglycan transpeptidase MecA -
  IAU62_RS10825 - 2259093..2259521 (-) 429 WP_000872606.1 MaoC family dehydratase -
  IAU62_RS10830 - 2259618..2260361 (-) 744 WP_000958858.1 glycerophosphoryl diester phosphodiesterase -
  IAU62_RS10835 - 2261278..2261667 (-) 390 WP_020444595.1 hydroxymethylglutaryl-CoA synthase -
  IAU62_RS10840 - 2261703..2262377 (+) 675 WP_001106057.1 IS6-like element IS257 family transposase -
  IAU62_RS10845 - 2262424..2262594 (+) 171 WP_155734542.1 hypothetical protein -
  IAU62_RS10850 - 2262627..2263538 (-) 912 WP_046464619.1 ABC transporter substrate-binding protein -
  IAU62_RS10855 - 2264169..2265683 (+) 1515 WP_046464618.1 hypothetical protein -
  IAU62_RS10860 ssb 2265854..2266147 (+) 294 WP_046464617.1 cassette chromosome ssDNA-binding protein -
  IAU62_RS10865 cch1 2266147..2267913 (+) 1767 WP_061544227.1 cassette chromosome replicative helicase -
  IAU62_RS10870 ccrA 2268124..2269485 (+) 1362 WP_061544228.1 cassette chromosome recombinase CcrA Machinery gene

Sequence

Protein


Download         Length: 453 a.a.        Molecular weight: 52936.78 Da        Isoelectric Point: 9.8297

>NTDB_id=479879 IAU62_RS10870 WP_061544228.1 2268124..2269485(+) (ccrA) [Staphylococcus epidermidis strain Z0118SE0132]
MEKAIAYVRQSTLKQQSLATQKSLIIDTAKQHGWSNVTFYDDKKTGGHTKRSGYQKMVEVITSGECKVLCCYRLNRLHRN
FKNAIQFFEICKKHHVTIISVNDGYFDLSKEFDCFRLNILMSLAEMESNNISEQTRNGIREKAKQGKLITTHAPFGYHYS
KGHFIVNAEEAPTIKAVYRWYLQGLGYKKISQKLDKDMNFISRKPYQVRNILLNPNYCGRVINKYGTFNDIVPPIINVDT
FEEAQERRIHKQHNRSNSRNKLKRRIKCPYCQSTLTNLTIKKEHRSLRYYVCPKNMNEAYHTCPFKGINAQMIETEVLNT
CKVYCGNQSFHDKLNETILKALKHQQMKHRQSHLTQEQLIEKLAQNQIDIETFKRLSAGFEREERYSNYSSNQIAETIRH
VVKDKLTLEIIAPLIDDITITQTKQLQGIYFKNSPLNIVEQSHLITPERNEVI

Nucleotide


Download         Length: 1362 bp        

>NTDB_id=479879 IAU62_RS10870 WP_061544228.1 2268124..2269485(+) (ccrA) [Staphylococcus epidermidis strain Z0118SE0132]
ATGGAAAAAGCCATTGCTTATGTACGTCAAAGTACACTCAAACAACAAAGCTTAGCGACTCAGAAATCCCTCATTATAGA
CACTGCTAAGCAACATGGATGGTCCAATGTAACATTTTATGATGATAAAAAAACAGGTGGACATACAAAGCGTTCAGGCT
ATCAAAAAATGGTAGAAGTGATTACATCTGGAGAGTGTAAAGTATTATGTTGCTATCGGCTAAATCGGCTCCATCGTAAT
TTCAAAAATGCTATACAATTCTTTGAAATTTGTAAAAAGCATCACGTCACAATCATCAGTGTTAACGATGGATATTTTGA
TTTGTCTAAAGAGTTTGATTGCTTTCGCTTAAACATACTCATGAGTCTAGCAGAAATGGAATCGAACAACATCAGCGAAC
AAACACGAAATGGGATAAGAGAAAAAGCCAAACAAGGTAAGTTGATTACAACACACGCCCCTTTTGGTTATCACTACAGC
AAAGGTCACTTTATTGTAAATGCAGAAGAAGCACCGACAATCAAAGCCGTTTATCGTTGGTATTTACAAGGACTTGGTTA
CAAGAAAATTTCTCAAAAGCTGGATAAAGATATGAATTTTATTTCTCGTAAGCCCTATCAAGTTAGAAATATTCTCTTGA
ACCCTAACTATTGTGGTCGTGTCATTAATAAATATGGAACGTTTAATGATATCGTTCCACCTATTATTAATGTTGATACG
TTTGAGGAAGCACAAGAGCGTCGTATTCATAAACAACACAATCGATCCAATTCTAGAAATAAGTTAAAGCGACGAATCAA
ATGTCCTTACTGTCAATCAACATTAACAAACTTAACGATAAAAAAAGAACATCGTTCTCTACGTTACTATGTCTGTCCTA
AAAATATGAATGAAGCCTATCATACGTGTCCATTTAAAGGCATCAATGCGCAAATGATTGAAACAGAGGTTCTAAACACT
TGTAAAGTATACTGTGGCAATCAATCATTTCATGACAAATTAAATGAGACAATACTAAAAGCTCTAAAACACCAACAAAT
GAAACACAGACAATCACATCTAACACAAGAACAACTCATCGAAAAACTAGCACAAAATCAAATTGATATAGAAACATTTA
AACGGTTATCTGCTGGCTTTGAAAGAGAAGAACGTTACTCTAATTATTCATCCAATCAAATTGCTGAAACAATCCGTCAT
GTAGTCAAAGATAAATTGACATTAGAAATCATAGCACCTTTGATTGATGACATTACAATAACTCAAACTAAACAATTACA
AGGAATCTACTTTAAAAACAGTCCACTCAATATCGTTGAACAATCGCATTTAATAACTCCTGAAAGGAATGAAGTCATAT
GA

Domains

Predicted by InterproScan.

Resolvase, N terminal domain (Resolvase)

(4-147)

Recombinase zinc beta ribbon domain (Zn_ribbon_recom)

(262-321)

Recombinase (Recombinase)

(169-248)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  ccrA Staphylococcus aureus COL

55.305

97.792

0.541
  ccrA Staphylococcus aureus N315

52.37

97.792

0.512