Detailed information    

insolico Bioinformatically predicted

Overview

Name   dprA   Type   Machinery gene
Locus tag   IAU62_RS03590 Genome accession   NZ_CP061029
Coordinates   704390..705265 (+) Length   291 a.a.
NCBI ID   WP_002499693.1    Uniprot ID   -
Organism   Staphylococcus epidermidis strain Z0118SE0132     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 668650..732616 704390..705265 within 0


Gene organization within MGE regions


Location: 668650..732616
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IAU62_RS03440 rlmN 668659..669753 (+) 1095 WP_002446258.1 23S rRNA (adenine(2503)-C(2))-methyltransferase RlmN -
  IAU62_RS03445 - 669760..670503 (+) 744 WP_002446259.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  IAU62_RS03450 pknB 670500..672500 (+) 2001 WP_002486274.1 Stk1 family PASTA domain-containing Ser/Thr kinase -
  IAU62_RS03455 rsgA 672809..673684 (+) 876 WP_002486277.1 ribosome small subunit-dependent GTPase A -
  IAU62_RS03460 rpe 673685..674329 (+) 645 WP_002446262.1 ribulose-phosphate 3-epimerase -
  IAU62_RS03465 - 674334..674969 (+) 636 WP_002446263.1 thiamine diphosphokinase -
  IAU62_RS03470 rpmB 675053..675241 (-) 189 WP_001830107.1 50S ribosomal protein L28 -
  IAU62_RS03475 - 675599..675973 (+) 375 WP_002446264.1 Asp23/Gls24 family envelope stress response protein -
  IAU62_RS03480 fakA 675988..677646 (+) 1659 WP_099774421.1 fatty acid kinase catalytic subunit FakA -
  IAU62_RS03485 recG 677850..679898 (+) 2049 WP_002446266.1 ATP-dependent DNA helicase RecG -
  IAU62_RS03490 fapR 680059..680619 (+) 561 WP_001830099.1 transcription factor FapR -
  IAU62_RS03495 plsX 680621..681598 (+) 978 WP_002457382.1 phosphate acyltransferase PlsX -
  IAU62_RS03500 fabD 681600..682529 (+) 930 WP_002486275.1 ACP S-malonyltransferase -
  IAU62_RS03505 fabG 682522..683256 (+) 735 WP_001830161.1 3-oxoacyl-[acyl-carrier-protein] reductase -
  IAU62_RS03510 - 683797..684030 (+) 234 WP_001830184.1 acyl carrier protein -
  IAU62_RS03515 rnc 684145..684882 (+) 738 WP_002446271.1 ribonuclease III -
  IAU62_RS03520 smc 685009..688578 (+) 3570 WP_002446272.1 chromosome segregation protein SMC -
  IAU62_RS03525 ftsY 688575..689801 (+) 1227 WP_099774419.1 signal recognition particle-docking protein FtsY -
  IAU62_RS03530 - 689803..690135 (+) 333 WP_002457379.1 putative DNA-binding protein -
  IAU62_RS03535 ffh 690166..691533 (+) 1368 WP_002446275.1 signal recognition particle protein -
  IAU62_RS03540 rpsP 691964..692239 (+) 276 WP_002439483.1 30S ribosomal protein S16 -
  IAU62_RS03545 rimM 692366..692869 (+) 504 WP_002487161.1 ribosome maturation factor RimM -
  IAU62_RS03550 trmD 692869..693606 (+) 738 WP_002457376.1 tRNA (guanosine(37)-N1)-methyltransferase TrmD -
  IAU62_RS03555 rplS 693712..694062 (+) 351 WP_002436293.1 50S ribosomal protein L19 -
  IAU62_RS03560 - 694241..696844 (-) 2604 WP_002475979.1 YfhO family protein -
  IAU62_RS03565 - 696837..699437 (-) 2601 WP_046044078.1 YfhO family protein -
  IAU62_RS03570 ylqF 699757..700620 (+) 864 WP_002457373.1 ribosome biogenesis GTPase YlqF -
  IAU62_RS03575 - 700625..701395 (+) 771 WP_002475250.1 ribonuclease HII -
  IAU62_RS03580 sucC 701503..702669 (+) 1167 WP_002439496.1 ADP-forming succinate--CoA ligase subunit beta -
  IAU62_RS03585 sucD 702691..703599 (+) 909 WP_002446283.1 succinate--CoA ligase subunit alpha -
  IAU62_RS12325 - 703796..703907 (+) 112 Protein_714 IS200/IS605 family transposase -
  IAU62_RS12330 - 703965..704065 (+) 101 Protein_715 IS200/IS605 family transposase -
  IAU62_RS03590 dprA 704390..705265 (+) 876 WP_002499693.1 DNA-processing protein DprA Machinery gene
  IAU62_RS03595 topA 705445..707514 (+) 2070 WP_187759524.1 type I DNA topoisomerase -
  IAU62_RS03600 trmFO 707539..708846 (+) 1308 WP_002475252.1 FADH(2)-oxidizing methylenetetrahydrofolate--tRNA-(uracil(54)-C(5))- methyltransferase TrmFO -
  IAU62_RS03605 xerC 709100..709960 (+) 861 WP_371091753.1 tyrosine recombinase XerC -
  IAU62_RS03610 hslV 709964..710506 (+) 543 WP_002446288.1 ATP-dependent protease subunit HslV -
  IAU62_RS03615 hslU 710576..711979 (+) 1404 WP_001829474.1 ATP-dependent protease ATPase subunit HslU -
  IAU62_RS03620 codY 712003..712776 (+) 774 WP_002446289.1 GTP-sensing pleiotropic transcriptional regulator CodY -
  IAU62_RS03625 rpsB 713133..713921 (+) 789 WP_001832557.1 30S ribosomal protein S2 -
  IAU62_RS03630 tsf 714073..714951 (+) 879 WP_002446291.1 translation elongation factor Ts -
  IAU62_RS03635 pyrH 715092..715814 (+) 723 WP_002439511.1 UMP kinase -
  IAU62_RS03640 frr 715831..716385 (+) 555 WP_002446292.1 ribosome recycling factor -
  IAU62_RS03645 - 716606..717376 (+) 771 WP_002446293.1 isoprenyl transferase -
  IAU62_RS03650 - 717380..718162 (+) 783 WP_001829499.1 phosphatidate cytidylyltransferase -
  IAU62_RS03655 rseP 718395..719681 (+) 1287 WP_002446294.1 RIP metalloprotease RseP -
  IAU62_RS03660 - 719700..721403 (+) 1704 WP_002476031.1 proline--tRNA ligase -
  IAU62_RS03665 - 721653..725963 (+) 4311 WP_088922878.1 PolC-type DNA polymerase III -
  IAU62_RS03670 rimP 726142..726609 (+) 468 WP_002446297.1 ribosome maturation factor RimP -
  IAU62_RS03675 nusA 726631..727854 (+) 1224 WP_002446298.1 transcription termination factor NusA -
  IAU62_RS03680 rnpM 727872..728156 (+) 285 WP_001829465.1 RNase P modulator RnpM -
  IAU62_RS03685 - 728156..728473 (+) 318 WP_002476037.1 YlxQ family RNA-binding protein -
  IAU62_RS03690 infB 728478..730640 (+) 2163 WP_002499691.1 translation initiation factor IF-2 -
  IAU62_RS03695 rbfA 730941..731291 (+) 351 WP_002457359.1 30S ribosome-binding factor RbfA -
  IAU62_RS03700 truB 731429..732346 (+) 918 WP_002446303.1 tRNA pseudouridine(55) synthase TruB -

Sequence

Protein


Download         Length: 291 a.a.        Molecular weight: 33932.07 Da        Isoelectric Point: 9.8284

>NTDB_id=479855 IAU62_RS03590 WP_002499693.1 704390..705265(+) (dprA) [Staphylococcus epidermidis strain Z0118SE0132]
MIQHTMLKLYWANFTTAQLHHLTRKYPGFLSENVFHQHDMIKRWLTERNSERLWNKYERFKKLKLMDIIKEMKKANVSFT
TYFDDNYPSLCKEMYDYPYVIFYKGNPQFFNHSHSLAVIGSRNATQYTSQSLNYLFPSFRQLNMAIVSGLARGADSVAHQ
TALKYFLPTIGVLGFGHCYHYPKATLNLRTKVERNGLVISEYPPFSPINKYKFPERNRLISGLSRGVLITEAEERSGSQI
TIDCALEQNRNVYVLPGSMFNKMTKGNLRRINEGAQVVIDESSILIDYLFM

Nucleotide


Download         Length: 876 bp        

>NTDB_id=479855 IAU62_RS03590 WP_002499693.1 704390..705265(+) (dprA) [Staphylococcus epidermidis strain Z0118SE0132]
TTGATACAACATACGATGTTAAAACTATATTGGGCAAATTTCACTACAGCACAACTTCATCATCTTACACGTAAATATCC
CGGCTTTCTATCAGAAAACGTATTTCATCAACATGACATGATAAAAAGGTGGCTTACAGAGCGTAATTCTGAAAGACTAT
GGAACAAATATGAACGTTTCAAAAAATTAAAGCTGATGGACATTATTAAAGAAATGAAAAAAGCAAATGTTAGTTTTACG
ACATACTTCGATGATAACTACCCTTCTCTTTGCAAAGAAATGTATGATTATCCTTATGTGATATTCTACAAAGGAAATCC
ACAGTTCTTTAATCATTCTCACTCTCTAGCTGTAATTGGCTCACGTAATGCCACACAATATACAAGTCAATCTTTAAACT
ATCTTTTTCCTTCATTTAGACAATTAAATATGGCGATTGTTTCTGGATTAGCGCGTGGCGCAGATAGTGTAGCACATCAA
ACCGCACTTAAATACTTTTTACCAACTATTGGCGTACTTGGATTTGGACATTGTTATCATTATCCTAAAGCAACCTTAAA
TTTAAGAACTAAAGTTGAAAGAAATGGCTTAGTGATAAGTGAATATCCACCATTTTCTCCCATAAATAAGTATAAATTTC
CTGAAAGAAACAGACTTATAAGTGGTCTGTCTAGAGGGGTTCTTATAACTGAGGCTGAAGAAAGAAGTGGTAGTCAAATT
ACTATTGATTGTGCTTTAGAGCAAAATAGAAATGTTTATGTTCTACCTGGTTCAATGTTCAACAAAATGACTAAAGGCAA
TTTACGAAGGATAAATGAAGGTGCTCAAGTTGTTATAGATGAAAGTAGTATCTTAATTGATTATCTATTTATGTAA

Domains

Predicted by InterproScan.

DNA recombination-mediator protein A (DNA_processg_A)

(72-279)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Staphylococcus aureus MW2

57.639

98.969

0.57
  dprA Staphylococcus aureus N315

57.639

98.969

0.57