Detailed information    

insolico Bioinformatically predicted

Overview

Name   comFA/cflA   Type   Machinery gene
Locus tag   IBB94_RS01985 Genome accession   NZ_CP061024
Coordinates   377850..379169 (+) Length   439 a.a.
NCBI ID   WP_207560143.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain 13498     
Function   ssDNA transport into the cell (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 372850..384169
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IBB94_RS01960 (IBB94_01955) - 373704..374468 (+) 765 WP_002949740.1 ABC transporter ATP-binding protein -
  IBB94_RS01965 (IBB94_01960) - 374468..375178 (+) 711 WP_014607989.1 ABC transporter ATP-binding protein -
  IBB94_RS01970 (IBB94_01965) - 375314..375974 (+) 661 Protein_341 CBS and ACT domain-containing protein -
  IBB94_RS01975 (IBB94_01970) cysK 376141..377067 (-) 927 WP_014607992.1 cysteine synthase A -
  IBB94_RS01980 (IBB94_01975) - 377169..377795 (-) 627 WP_011225515.1 YigZ family protein -
  IBB94_RS01985 (IBB94_01980) comFA/cflA 377850..379169 (+) 1320 WP_207560143.1 DEAD/DEAH box helicase Machinery gene
  IBB94_RS01990 (IBB94_01985) - 379150..379812 (+) 663 WP_014607994.1 ComF family protein -
  IBB94_RS01995 (IBB94_01990) raiA 379891..380439 (+) 549 WP_011680772.1 ribosome-associated translation inhibitor RaiA -

Sequence

Protein


Download         Length: 439 a.a.        Molecular weight: 50538.65 Da        Isoelectric Point: 9.5841

>NTDB_id=479749 IBB94_RS01985 WP_207560143.1 377850..379169(+) (comFA/cflA) [Streptococcus thermophilus strain 13498]
MIPKEYYGRLFTKEQLPVDYLSEAVKLESMIKVDKKLRCKRCYSRIEEDWQLPNGQYYCRACIVFGRNQEGKELYYFPSE
KSEVDFPVLKWSGKLTPYQNEVSEKLLKTYKNQKHSLVHAVTGAGKTEMIYNIVAYVLENKNRVVIASPRVDVCRELFLR
MQKDFTCSISLLHADSEPYDGSPLVIATTHQLLKFYHSFDLIIIDEVDAFPFVGNVMLNHAVKQAKTETGRYIYLTATST
LALEEQVRLGAIEKHHLASRFHGNPLVLPCFFWQGRLQKSLTSDKLPRPLIHQIKKQRKSNFPLLIFFPNIALGEKFSIT
LKKYLPTENIAFVSSKSEERSTIVEKFRKKELSILVTTTILERGVTFSQVDVFVCMANHHLYTSSSLIQIGGRVGRSPER
PTGKLYFFHEGLSKSMLQCRKEINAMNKKGGFENEVSTM

Nucleotide


Download         Length: 1320 bp        

>NTDB_id=479749 IBB94_RS01985 WP_207560143.1 377850..379169(+) (comFA/cflA) [Streptococcus thermophilus strain 13498]
ATGATACCTAAAGAATATTATGGACGACTATTTACGAAAGAACAGTTACCAGTGGATTATCTCTCAGAGGCTGTAAAATT
AGAAAGTATGATAAAGGTTGATAAAAAACTTAGATGTAAAAGATGTTATAGTCGAATAGAGGAAGATTGGCAATTACCGA
ATGGTCAGTATTATTGTAGAGCGTGTATTGTCTTTGGTCGAAACCAAGAAGGAAAAGAACTCTATTACTTTCCCTCAGAA
AAATCAGAAGTAGATTTTCCTGTCTTGAAATGGTCAGGAAAACTGACTCCTTATCAAAATGAGGTCTCGGAAAAGCTTTT
AAAGACTTATAAAAATCAAAAACACAGTCTTGTTCATGCAGTGACTGGTGCTGGCAAGACAGAGATGATTTATAATATTG
TTGCCTATGTTCTTGAAAATAAAAATCGTGTCGTCATCGCAAGTCCCCGAGTTGATGTTTGTCGAGAATTGTTTCTACGC
ATGCAGAAAGATTTTACTTGTAGTATTTCTCTGCTTCATGCTGATAGTGAACCATATGATGGTAGTCCGCTCGTTATAGC
TACCACTCATCAATTACTAAAATTTTATCATAGCTTTGACTTGATTATTATTGACGAAGTTGATGCCTTTCCATTTGTAG
GGAATGTCATGTTAAATCATGCTGTTAAACAGGCAAAGACGGAAACAGGCCGGTATATTTACTTAACAGCAACTTCTACA
TTAGCTTTAGAAGAGCAAGTGCGCCTTGGAGCTATAGAAAAGCATCACCTTGCTAGTCGTTTCCACGGAAATCCTTTAGT
CCTTCCTTGTTTCTTTTGGCAAGGAAGGTTACAAAAGTCGTTGACGAGCGATAAGCTTCCAAGGCCTCTAATTCACCAGA
TTAAGAAGCAGCGTAAATCAAATTTTCCTCTATTAATCTTTTTCCCCAATATAGCATTAGGTGAAAAGTTTAGTATTACC
CTAAAAAAATATCTCCCTACTGAAAACATAGCCTTTGTTTCATCAAAAAGCGAGGAGCGTTCAACCATCGTAGAGAAATT
CCGAAAAAAAGAATTGTCAATCTTAGTGACGACAACTATTCTCGAACGTGGTGTTACCTTTTCACAAGTAGATGTTTTTG
TTTGTATGGCAAATCATCACTTATATACTAGTTCGAGTCTTATTCAGATTGGTGGTAGGGTGGGGCGTTCGCCCGAGAGA
CCTACAGGGAAACTCTATTTCTTTCATGAAGGATTATCTAAATCAATGTTGCAATGTCGGAAAGAAATAAATGCAATGAA
TAAAAAAGGAGGGTTTGAAAATGAAGTGTCTACTATGTAA

Domains

Predicted by InterproScan.

Helicase conserved C-terminal domain (Helicase_C)

(290-396)

Type III restriction enzyme, res subunit (ResIII)

(94-207)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comFA/cflA Streptococcus pneumoniae Rx1

54.756

98.178

0.538
  comFA/cflA Streptococcus pneumoniae D39

54.756

98.178

0.538
  comFA/cflA Streptococcus pneumoniae R6

54.756

98.178

0.538
  comFA/cflA Streptococcus pneumoniae TIGR4

54.756

98.178

0.538
  comFA/cflA Streptococcus mitis NCTC 12261

54.419

97.95

0.533
  comFA/cflA Streptococcus mitis SK321

53.488

97.95

0.524
  comFA Lactococcus lactis subsp. cremoris KW2

46.429

95.672

0.444
  comFA Latilactobacillus sakei subsp. sakei 23K

36.782

99.089

0.364