Detailed information NTG0479527

Bioinformatically predicted

Overview

• Name: ccpA
• Type: Regulator
• Locus tag: IBC04_RS03250
• Genome accession: NZ_CP061020
• Coordinates: 609729..610730 (+)
• Length: 333 a.a.
• NCBI ID: WP_004197422.1
• Uniprot ID: Q9L6X0
• Organism: Streptococcus thermophilus strain 24740
• Function: require for competence development (predicted from homology) Competence regulation

Genomic Context

Location: 604729..615730

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
IBC04_RS03230 (IBC04_03225)	smpB	605836..606300 (+)	465	WP_002950240.1	SsrA-binding protein SmpB	-
IBC04_RS03235 (IBC04_03230)	-	606454..607860 (+)	1407	WP_011680934.1	Cof-type HAD-IIB family hydrolase	-
IBC04_RS03240 (IBC04_03235)	-	607862..608227 (+)	366	WP_002950243.1	S1 RNA-binding domain-containing protein	-
IBC04_RS03245 (IBC04_03240)	-	608330..609415 (-)	1086	WP_011680935.1	Xaa-Pro peptidase family protein	-
IBC04_RS03250 (IBC04_03245)	ccpA	609729..610730 (+)	1002	WP_004197422.1	catabolite control protein A	Regulator
IBC04_RS03255 (IBC04_03250)	-	610789..610986 (+)	198	WP_014608125.1	hypothetical protein	-
IBC04_RS10050	-	611092..611316 (+)	225	WP_224102938.1	MmcQ/YjbR family DNA-binding protein	-
IBC04_RS03260 (IBC04_03255)	-	611317..611856 (+)	540	WP_011680936.1	hypothetical protein	-
IBC04_RS03265 (IBC04_03260)	-	611869..612984 (+)	1116	WP_011680937.1	glycerate kinase	-
IBC04_RS03270 (IBC04_03265)	-	613031..613486 (-)	456	WP_011680938.1	YueI family protein	-
IBC04_RS03275 (IBC04_03270)	eno	613695..614999 (+)	1305	WP_022096978.1	surface-displayed alpha-enolase	-
IBC04_RS03280 (IBC04_03275)	-	615151..615336 (-)	186	WP_011680940.1	hypothetical protein	-

Sequence

Protein

• Length: 333 a.a.
• Molecular weight: 36597.53 Da
• Isoelectric Point: 5.8841

>NTDB_id=479527 IBC04_RS03250 WP_004197422.1 609729..610730(+) (ccpA) [Streptococcus thermophilus strain 24740]
MNTDETITIYDVAREAGVSMATVSRVVNGNKNVKENTRKKVLEVIDRLDYRPNAVARGLASKKTTTVGVVIPNIVNSYFA
TLAKGIDDIATMYKYNIVLASSDDNEDHEVTVIHSLISKQVDGIIFMGHHLTEKIRAEFSRTRTPIVLAGTVDLEHQLPS
VNIDYKAAVEDCVTQLAKNNEKVAFVSGPLIDDINGKLRLAGYKSGLEKNNLSYNEGLVFEAKYSYKDGFELAQRVLNSG
ATAAYVGEDELAAGLLNGLFAAGKSVPEDFEIITSNDSPVTSYTRPNLSSINHPLYDLGAVSMRMLTKIMHKEELEDKDV
ILNHGLTLRQSTK

Nucleotide

• Length: 1002 bp

>NTDB_id=479527 IBC04_RS03250 WP_004197422.1 609729..610730(+) (ccpA) [Streptococcus thermophilus strain 24740]
ATGAATACTGATGAAACAATCACAATTTATGATGTAGCGCGTGAAGCTGGAGTATCGATGGCAACTGTTTCTCGTGTTGT
AAATGGTAACAAAAACGTAAAAGAAAACACCCGAAAAAAAGTGCTCGAAGTCATTGATCGTTTGGATTACCGTCCAAATG
CGGTTGCGCGTGGCTTGGCAAGTAAAAAAACAACTACTGTAGGAGTTGTCATTCCAAATATTGTAAATAGCTATTTTGCT
ACTCTAGCTAAAGGTATTGATGACATTGCAACCATGTATAAGTATAATATTGTTCTTGCTTCCAGTGATGATAATGAGGA
TCATGAAGTTACAGTCATTCATTCTCTAATTTCTAAACAAGTTGATGGTATTATTTTTATGGGACACCATCTGACAGAAA
AAATCCGTGCAGAATTCTCTCGTACCCGTACACCGATTGTTCTAGCAGGAACAGTTGATCTCGAACACCAATTACCAAGT
GTTAACATCGACTATAAAGCTGCCGTTGAGGATTGTGTAACGCAACTTGCTAAAAATAATGAAAAGGTTGCCTTTGTATC
AGGACCACTAATTGATGATATTAATGGCAAACTACGTTTGGCCGGGTATAAGTCTGGACTTGAAAAGAATAATTTGAGCT
ACAACGAAGGACTTGTCTTTGAAGCTAAATATAGCTATAAAGACGGCTTTGAGTTAGCACAACGTGTCTTGAACTCTGGT
GCCACTGCTGCCTATGTTGGGGAAGATGAATTGGCTGCAGGTCTCTTGAATGGCCTCTTTGCTGCAGGCAAATCAGTTCC
AGAAGATTTCGAAATCATCACAAGCAATGATTCACCGGTTACAAGCTACACACGTCCAAACCTTTCTAGTATAAACCATC
CTCTCTATGATTTAGGGGCAGTTAGCATGCGTATGTTGACTAAAATTATGCATAAGGAAGAACTTGAAGATAAAGACGTT
ATTCTTAATCATGGTCTAACTTTACGCCAGTCAACAAAATAA

Domains

Predicted by InterproScan.

• Periplasmic binding protein-like domain (Peripla_BP_3) (182-332)

• Bacterial regulatory proteins, lacI family (LacI) (8-53)

3D structure

• AlphaFold DB: Q9L6X0

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ccpA	Streptococcus gordonii str. Challis substr. CH1	76.276	100	0.763
ccpA	Streptococcus pneumoniae D39	75.375	100	0.754
ccpA	Lactococcus lactis subsp. lactis strain DGCC12653	54.985	99.399	0.547