Detailed information NTG0479350

Bioinformatically predicted

Overview

• Name: braR
• Type: Regulator
• Locus tag: J4Q30_RS07925
• Genome accession: NZ_CP071917
• Coordinates: 1535470..1536147 (-)
• Length: 225 a.a.
• NCBI ID: WP_000548959.1
• Uniprot ID: Q9S1K2
• Organism: Streptococcus pneumoniae strain 19A-19339
• Function: promote expression of competence genes (predicted from homology) Competence regulation

Genomic Context

Location: 1530470..1541147

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
J4Q30_RS07895 (J4Q30_07910)	-	1530633..1531262 (-)	630	WP_000762091.1	NAD(P)-dependent oxidoreductase	-
J4Q30_RS07900 (J4Q30_07915)	-	1531500..1531700 (+)	201	WP_001814296.1	hypothetical protein	-
J4Q30_RS07905 (J4Q30_07920)	-	1532130..1532270 (+)	141	WP_000422775.1	MazG-like protein	-
J4Q30_RS07910 (J4Q30_07925)	-	1532277..1532453 (+)	177	WP_000166031.1	MazG-like protein	-
J4Q30_RS07915 (J4Q30_07930)	thrS	1532511..1534454 (+)	1944	WP_000608349.1	threonine--tRNA ligase	-
J4Q30_RS07920 (J4Q30_07935)	-	1534503..1535477 (-)	975	WP_000887953.1	HAMP domain-containing histidine kinase	-
J4Q30_RS07925 (J4Q30_07940)	braR	1535470..1536147 (-)	678	WP_000548959.1	response regulator transcription factor	Regulator
J4Q30_RS07930 (J4Q30_07945)	-	1536303..1537376 (+)	1074	WP_001273823.1	DUF2974 domain-containing protein	-
J4Q30_RS07935 (J4Q30_07950)	-	1537467..1537769 (-)	303	WP_000281609.1	hypothetical protein	-
J4Q30_RS07940 (J4Q30_07955)	-	1537837..1538274 (-)	438	WP_001166785.1	Rrf2 family transcriptional regulator	-
J4Q30_RS07945 (J4Q30_07960)	-	1538350..1539192 (-)	843	WP_000160938.1	metallophosphoesterase	-
J4Q30_RS07950 (J4Q30_07965)	-	1539304..1539954 (+)	651	WP_000188505.1	metal-dependent transcriptional regulator	-
J4Q30_RS11780 (J4Q30_07970)	-	1539935..1540126 (+)	192	WP_001816503.1	hypothetical protein	-
J4Q30_RS07955 (J4Q30_07975)	-	1540152..1540827 (+)	676	Protein_1595	nicotinamide mononucleotide transporter	-
J4Q30_RS11855	-	1540929..1541000 (+)	72	Protein_1596	glutamine ABC transporter permease	-

Sequence

Protein

• Length: 225 a.a.
• Molecular weight: 25964.16 Da
• Isoelectric Point: 5.1362

>NTDB_id=479350 J4Q30_RS07925 WP_000548959.1 1535470..1536147(-) (braR) [Streptococcus pneumoniae strain 19A-19339]
MHKILLIEDDQVIRQQIGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide

• Length: 678 bp

>NTDB_id=479350 J4Q30_RS07925 WP_000548959.1 1535470..1536147(-) (braR) [Streptococcus pneumoniae strain 19A-19339]
ATGCACAAGATTTTATTAATAGAAGATGATCAGGTCATTCGTCAACAGATTGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTCTATTTGTTCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGGGCGGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCTAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTCTTGAATTTGACCAAGAATGAATTCCAGATTTTA
CGCGTGTTATTTGAGCATGCAGGCAACATCGTAGCACGTGACGACCTGATGCGGGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

• Response regulator receiver domain (Response_reg) (4-112)

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (147-221)

3D structure

• AlphaFold DB: Q9S1K2

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
braR	Staphylococcus aureus N315	48.624	96.889	0.471
vicR	Streptococcus mutans UA159	35.319	100	0.369