Detailed information NTG0047932

Bioinformatically predicted

Overview

• Name: comP
• Type: Machinery gene
• Locus tag: NMBG2136_RS10635
• Genome accession: NC_017513
• Coordinates: 2049042..2049491 (-)
• Length: 149 a.a.
• NCBI ID: WP_002221685.1
• Uniprot ID: A1KW94
• Organism: Neisseria meningitidis G2136
• Function: DNA binding; DNA uptake; receptor of DNA uptake sequence (DUS) (predicted from homology) DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IScluster/Tn	2047004..2048345	2049042..2049491	flank	697

Gene organization within MGE regions

Location: 2047004..2049491

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
NMBG2136_RS10625 (NMBG2136_1908)	-	2047004..2047969 (+)	966	WP_002221064.1	IS30-like element IS1655 family transposase	-
NMBG2136_RS13275	-	2047995..2048345 (-)	351	Protein_1971	IS5/IS1182 family transposase	-
NMBG2136_RS15580 (NMBG2136_1909)	-	2048684..2048952 (+)	269	Protein_1972	5'-nucleotidase	-
NMBG2136_RS10635 (NMBG2136_1910)	comP	2049042..2049491 (-)	450	WP_002221685.1	type IV pilin protein	Machinery gene

Sequence

Protein

• Length: 149 a.a.
• Molecular weight: 16848.83 Da
• Isoelectric Point: 9.7951

>NTDB_id=47932 NMBG2136_RS10635 WP_002221685.1 2049042..2049491(-) (comP) [Neisseria meningitidis G2136]
MTDNRGFTLVELISVVLILSVLALIVYPSYRNYIEKAKINAVRAALLENAHFMEKFYLQNGRFKQTSTKWPSLPIKEAEG
FCIRLNGIARGALDSKFMLKAVAIDKDKNPFIIKMNENLVTFICKKSASSCSDGLDYFKGNDKDCKLLK

Nucleotide

• Length: 450 bp

>NTDB_id=47932 NMBG2136_RS10635 WP_002221685.1 2049042..2049491(-) (comP) [Neisseria meningitidis G2136]
ATGACTGATAATCGGGGGTTTACGCTGGTTGAATTAATATCAGTGGTCTTGATATTGTCTGTACTTGCTTTAATTGTTTA
TCCGAGCTATCGCAATTATATTGAGAAAGCAAAGATAAATGCAGTGCGGGCAGCCTTGTTAGAAAATGCACATTTTATGG
AAAAGTTTTATCTGCAGAATGGGAGATTTAAACAAACATCTACCAAATGGCCAAGTTTGCCGATTAAAGAGGCAGAAGGC
TTTTGTATCCGTTTGAATGGAATCGCGCGCGGGGCCTTAGACAGTAAATTCATGTTGAAGGCGGTAGCCATAGATAAAGA
TAAAAATCCTTTTATTATTAAGATGAATGAAAATCTAGTAACCTTTATTTGCAAGAAGTCCGCCAGTTCGTGTAGTGACG
GGCTGGATTATTTTAAAGGAAATGATAAGGACTGCAAGTTACTTAAGTAG

Domains

Predicted by InterproScan.

• Type IV minor pilin ComP, DNA uptake sequence receptor (ComP_DUS) (28-107)

• Prokaryotic N-terminal methylation motif (N_methyl) (1-27)

3D structure

• AlphaFold DB: A1KW94

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comP	Neisseria gonorrhoeae MS11	99.329	100	0.993
comP	Neisseria meningitidis 8013	98.658	100	0.987
comP	Neisseria subflava NJ9703	48.98	98.658	0.483