Detailed information    

insolico Bioinformatically predicted

Overview

Name   uvrC   Type   Machinery gene
Locus tag   JN057_RS03045 Genome accession   NZ_CP071871
Coordinates   581395..583239 (+) Length   614 a.a.
NCBI ID   WP_001061132.1    Uniprot ID   C1CJ89
Organism   Streptococcus pneumoniae strain BVJ1JL     
Function   homologous recombination (predicted from homology)   
Homologous recombination

Genomic Context

Location: 576395..588239
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JN057_RS03025 (JN057_00623) - 577227..578006 (+) 780 WP_000290022.1 alpha/beta hydrolase -
  JN057_RS03030 (JN057_00624) murM 578118..579338 (+) 1221 WP_001816673.1 peptidoglycan bridge formation alanyltransferase MurM -
  JN057_RS03035 (JN057_00625) murN 579343..580575 (+) 1233 WP_001229509.1 peptidoglycan bridge formation alanyltransferase MurN -
  JN057_RS03040 (JN057_00626) - 580654..581355 (+) 702 WP_001267410.1 M57 family metalloprotease -
  JN057_RS03045 (JN057_00627) uvrC 581395..583239 (+) 1845 WP_001061132.1 excinuclease ABC subunit UvrC Machinery gene
  JN057_RS03050 (JN057_00628) - 583229..584026 (+) 798 WP_001015781.1 metallophosphoesterase family protein -
  JN057_RS03055 (JN057_00629) - 584208..585008 (-) 801 WP_000736538.1 amino acid ABC transporter substrate-binding protein -
  JN057_RS03060 (JN057_00630) - 585179..585784 (+) 606 WP_000670162.1 nitroreductase family protein -
  JN057_RS03065 (JN057_00631) pepV 585797..587197 (+) 1401 WP_000125039.1 dipeptidase PepV -
  JN057_RS03070 (JN057_00632) - 587251..587829 (+) 579 WP_000078149.1 uracil-DNA glycosylase family protein -

Sequence

Protein


Download         Length: 614 a.a.        Molecular weight: 70436.96 Da        Isoelectric Point: 9.1183

>NTDB_id=479071 JN057_RS03045 WP_001061132.1 581395..583239(+) (uvrC) [Streptococcus pneumoniae strain BVJ1JL]
MNNLIKSKLELLPTSPGCYIHKDKNGTIIYVGKAKNLRNRVRSYFRGSHDTKTEALVSEIVDFEFIVTESNIEALLLEIN
LIKENKPKYNIMLKDDKSYPFIKITNERYPRLIITRQVKKDGGLYFGPYPDVGAANEIKRLLDRIFPFRKCTNPPSKVCF
YYHIGQCMAHTICKKDEAYFKSMAQEVSDFLKGQDDKIIDDLKSKMAVAAQSMEFERAAEYRDLIQAIGTLRTKQRVMAK
DLQNRDVFGYYVDKGWMCVQVFFVRQGKLIERDVNLFPYFNDPDEDFLTYVGQFYQEKSHLVPNEVLIPQDIDEEAVKAL
VDSKILKPQRGEKKQLVNLAIKNARVSLEQKFNLLEKSVEKTQGAIENLGRLLQIPTPVRIESFDNSNIMGTSPVSAMVV
FVNGKPSKKDYRKYKIKTVVGPDDYASMREVIRRRYGRVQREALTPPDLIVIDGGQGQVNIAKQVIQEELGLDIPIAGLQ
KNDKHQTHELLFGDPLEVVDLSRNSQEFFLLQRIQDEVHRFAITFHRQLRSKNSFSSQLDGIDGLGPKRKQNLMRHFKSL
TKIKEASVDEIVEVGVPRVVAEAVQRKLNPQGEALPQVAEERVDYQTEGNHNEP

Nucleotide


Download         Length: 1845 bp        

>NTDB_id=479071 JN057_RS03045 WP_001061132.1 581395..583239(+) (uvrC) [Streptococcus pneumoniae strain BVJ1JL]
ATGAACAACTTGATTAAATCAAAACTAGAGCTCTTGCCGACCAGCCCTGGTTGCTACATTCATAAGGATAAAAATGGCAC
CATTATCTATGTAGGAAAGGCTAAAAATCTGCGTAATCGAGTACGGTCCTATTTTCGTGGAAGTCATGATACCAAGACAG
AGGCTCTGGTGTCTGAAATTGTGGATTTTGAATTTATTGTTACGGAGTCTAATATTGAGGCACTTCTCCTAGAAATCAAC
CTGATCAAGGAAAACAAGCCCAAGTACAATATCATGCTCAAGGATGACAAGTCCTATCCTTTCATCAAAATCACCAATGA
GCGCTATCCACGGCTTATCATTACTCGTCAGGTCAAAAAGGACGGTGGTCTTTATTTTGGCCCTTATCCAGATGTGGGGG
CAGCCAATGAAATCAAGCGACTTCTAGATAGGATTTTCCCTTTTCGAAAATGTACCAACCCGCCCTCTAAGGTCTGTTTT
TATTACCATATCGGCCAGTGTATGGCCCACACCATCTGTAAGAAGGATGAGGCTTATTTCAAGTCTATGGCTCAGGAGGT
GTCTGATTTTCTGAAAGGTCAGGATGACAAAATCATCGATGATCTCAAGAGTAAAATGGCAGTAGCAGCACAAAGTATGG
AGTTTGAACGTGCGGCGGAATACCGTGACCTGATTCAGGCTATTGGAACGCTTCGAACCAAGCAACGGGTCATGGCGAAA
GATTTGCAAAATCGCGATGTCTTTGGCTACTATGTGGATAAGGGCTGGATGTGTGTGCAGGTTTTCTTTGTCCGTCAGGG
TAAGCTTATCGAGCGCGATGTCAATCTCTTCCCCTACTTCAATGATCCAGATGAGGATTTTTTGACCTATGTAGGACAAT
TCTATCAAGAAAAATCTCATCTAGTTCCCAATGAGGTACTGATTCCGCAGGATATTGACGAAGAGGCTGTCAAGGCCTTG
GTGGATTCCAAGATTCTTAAGCCTCAACGTGGAGAGAAAAAACAACTGGTCAATCTAGCCATAAAAAATGCTCGTGTTAG
TCTAGAGCAGAAGTTCAATCTGCTAGAAAAATCTGTCGAAAAGACTCAAGGAGCTATTGAAAATCTAGGGCGTTTGCTCC
AAATCCCGACCCCAGTACGTATCGAGTCCTTCGATAACTCTAATATCATGGGAACTAGCCCTGTTTCGGCTATGGTGGTC
TTTGTCAACGGTAAACCGAGTAAGAAGGATTACCGTAAGTACAAGATAAAAACGGTTGTTGGACCAGACGACTATGCCAG
CATGAGAGAGGTCATTCGCAGACGCTATGGTCGAGTACAGCGTGAGGCTTTGACTCCTCCAGATTTGATTGTGATTGATG
GGGGGCAAGGTCAAGTCAATATCGCTAAGCAGGTTATCCAAGAGGAACTGGGCTTGGATATTCCAATTGCTGGGCTGCAA
AAGAATGATAAGCACCAAACCCATGAATTGCTCTTTGGAGATCCGCTTGAGGTGGTGGACTTGTCTCGCAATTCTCAGGA
ATTTTTCCTCCTCCAACGCATCCAAGATGAGGTGCACCGCTTTGCTATCACTTTCCACCGCCAACTGCGCTCCAAAAATT
CTTTCTCATCTCAATTGGATGGGATTGATGGTCTGGGACCTAAACGCAAGCAAAATCTCATGAGGCATTTCAAGTCTTTG
ACCAAAATCAAGGAAGCCAGTGTGGATGAGATTGTCGAAGTTGGGGTACCTAGAGTCGTTGCAGAGGCTGTGCAAAGAAA
GTTGAACCCGCAGGGAGAAGCCTTGCCTCAAGTAGCAGAAGAAAGAGTAGATTACCAAACGGAAGGAAACCACAATGAAC
CATAA

Domains

Predicted by InterProScan.

UvrB/uvrC motif (UVR)

(196-228)

UvrC RNAse H endonuclease domain (UvrC_RNaseH_dom)

(372-523)

GIY-YIG catalytic domain (GIY-YIG)

(17-90)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB C1CJ89

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  uvrC Streptococcus pneumoniae TIGR4

99.837

100

0.998
  uvrC Streptococcus pneumoniae R6

99.674

100

0.997
  uvrC Streptococcus pneumoniae D39

99.674

100

0.997