Detailed information
Bioinformatically predicted
Overview
| Name | comE | Type | Machinery gene |
| Locus tag | NMAA_RS11510 | Genome accession | NC_017512 |
| Coordinates | 2187684..2188148 (-) | Length | 154 a.a. |
| NCBI ID | WP_010981060.1 | Uniprot ID | - |
| Organism | Neisseria meningitidis WUE 2594 | ||
| Function | DNA binding (predicted from homology) DNA binding and uptake |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| Genomic island | 2168383..2194367 | 2187684..2188148 | within | 0 |
Gene organization within MGE regions
Location: 2168383..2194367
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| NMAA_RS11415 (NMAA_1896) | - | 2168383..2169246 (-) | 864 | WP_002236576.1 | galactosyltransferase-related protein | - |
| NMAA_RS11420 (NMAA_1897) | - | 2169248..2169991 (-) | 744 | WP_002236577.1 | YqiA/YcfP family alpha/beta fold hydrolase | - |
| NMAA_RS11425 (NMAA_1898) | - | 2170064..2171701 (-) | 1638 | WP_002236578.1 | stealth family protein | - |
| NMAA_RS11430 (NMAA_1899) | wecB | 2171703..2172821 (-) | 1119 | WP_002236579.1 | non-hydrolyzing UDP-N-acetylglucosamine 2-epimerase | - |
| NMAA_RS11435 (NMAA_1900) | ctrA | 2173040..2174203 (+) | 1164 | WP_014580711.1 | capsule polysaccharide export outer membrane protein CtrA | - |
| NMAA_RS11440 (NMAA_1901) | - | 2174218..2175381 (+) | 1164 | WP_002236581.1 | capsule polysaccharide export inner-membrane protein CtrB | - |
| NMAA_RS11445 (NMAA_1902) | - | 2175381..2176178 (+) | 798 | WP_002236582.1 | ABC transporter permease | - |
| NMAA_RS11450 (NMAA_1903) | - | 2176175..2176825 (+) | 651 | WP_002218516.1 | ABC transporter ATP-binding protein | - |
| NMAA_RS11455 (NMAA_1904) | - | 2176889..2179162 (+) | 2274 | WP_002239407.1 | Tex family protein | - |
| NMAA_RS11460 (NMAA_ps128) | - | 2179193..2180023 (+) | 831 | WP_002215283.1 | DNA cytosine methyltransferase | - |
| NMAA_RS15620 | - | 2180001..2180195 (+) | 195 | WP_002215282.1 | DNA cytosine methyltransferase | - |
| NMAA_RS11470 (NMAA_ps129) | - | 2180188..2180532 (+) | 345 | WP_002231447.1 | DNA adenine methylase | - |
| NMAA_RS11475 (NMAA_ps130) | galE | 2180611..2181231 (+) | 621 | Protein_2155 | UDP-glucose 4-epimerase GalE | - |
| NMAA_RS11480 (NMAA_1905) | rfbB | 2181347..2182372 (+) | 1026 | WP_002236574.1 | dTDP-glucose 4,6-dehydratase | - |
| NMAA_RS11485 (NMAA_1906) | rfbA | 2182478..2183344 (+) | 867 | WP_002221803.1 | glucose-1-phosphate thymidylyltransferase RfbA | - |
| NMAA_RS11490 (NMAA_1907) | rfbC | 2183398..2183955 (+) | 558 | WP_002249566.1 | dTDP-4-dehydrorhamnose 3,5-epimerase | - |
| NMAA_RS11495 (NMAA_1908) | - | 2183998..2186016 (-) | 2019 | WP_002236572.1 | OPT family oligopeptide transporter | - |
| NMAA_RS11500 (NMAA_1909) | dnaJ | 2186211..2187332 (-) | 1122 | WP_002215274.1 | molecular chaperone DnaJ | - |
| NMAA_RS15110 | - | 2187414..2187572 (-) | 159 | WP_002215272.1 | hypothetical protein | - |
| NMAA_RS11510 (NMAA_1910) | comE | 2187684..2188148 (-) | 465 | WP_010981060.1 | ComEA family DNA-binding protein | Machinery gene |
| NMAA_RS11540 (NMAA_1911) | dksA | 2193951..2194367 (-) | 417 | WP_002238569.1 | RNA polymerase-binding protein DksA | - |
Sequence
Protein
Download Length: 154 a.a. Molecular weight: 16529.75 Da Isoelectric Point: 10.6993
>NTDB_id=47885 NMAA_RS11510 WP_010981060.1 2187684..2188148(-) (comE) [Neisseria meningitidis WUE 2594]
MLCPEKMSGMAGQYPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASQQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKGPAKPVLPADKK
MLCPEKMSGMAGQYPYGVRSGLRRNGLKLWDIHFRMTRFIVARCGLLFATLKGKTMKKMFVLFCMLFSCAFSLAAVNINA
ASQQELEALPGIGPAKAKAIAEYRAQNGAFKSVDDLTKVKGIGPAVLAKLKDQASVGAPAPKGPAKPVLPADKK
Nucleotide
Download Length: 465 bp
>NTDB_id=47885 NMAA_RS11510 WP_010981060.1 2187684..2188148(-) (comE) [Neisseria meningitidis WUE 2594]
TTGCTTTGCCCGGAAAAAATGTCGGGGATGGCGGGACAGTATCCGTACGGCGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACTCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCAGCAGGAGTTGGAGGCGCTGCCGGGCATAGGCCCTGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTAGACGATTTGACCAAGGTAAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGATCAGG
CTTCGGTCGGTGCGCCCGCACCAAAAGGCCCAGCCAAACCAGTGCTGCCCGCGGATAAAAAATAG
TTGCTTTGCCCGGAAAAAATGTCGGGGATGGCGGGACAGTATCCGTACGGCGTCCGGTCGGGTTTGCGGAGGAACGGCTT
GAAACTTTGGGATATTCATTTTAGAATGACTCGTTTTATCGTCGCAAGATGCGGTTTATTGTTTGCAACCCTTAAAGGAA
AAACCATGAAGAAAATGTTCGTGCTGTTCTGTATGCTGTTCTCCTGCGCCTTCTCCCTTGCGGCGGTAAACATCAATGCG
GCTTCGCAGCAGGAGTTGGAGGCGCTGCCGGGCATAGGCCCTGCGAAGGCGAAGGCCATTGCGGAATACCGTGCGCAAAA
CGGTGCGTTCAAGTCTGTAGACGATTTGACCAAGGTAAAGGGCATCGGCCCTGCGGTGCTGGCGAAGCTGAAGGATCAGG
CTTCGGTCGGTGCGCCCGCACCAAAAGGCCCAGCCAAACCAGTGCTGCCCGCGGATAAAAAATAG
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| comE | Neisseria gonorrhoeae MS11 |
94.262 |
79.221 |
0.747 |
| comE | Neisseria gonorrhoeae MS11 |
94.262 |
79.221 |
0.747 |
| comE | Neisseria gonorrhoeae MS11 |
94.262 |
79.221 |
0.747 |
| comE | Neisseria gonorrhoeae MS11 |
94.262 |
79.221 |
0.747 |