Detailed information NTG0047853

Bioinformatically predicted

Overview

• Name: comR
• Type: Regulator
• Locus tag: SPN994039_RS09505
• Genome accession: NC_021005
• Coordinates: 1764446..1765345 (-)
• Length: 299 a.a.
• NCBI ID: WP_000904867.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae SPN994039
• Function: activate transcription of comX (predicted from homology) Competence regulation

Genomic Context

Location: 1759446..1770345

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SPN994039_RS09480 (SPN994039_17370)	rsmA	1759776..1760648 (-)	873	WP_001216830.1	16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))- dimethyltransferase RsmA	-
SPN994039_RS09485 (SPN994039_17380)	-	1760779..1761087 (-)	309	WP_000333257.1	hypothetical protein	-
SPN994039_RS09490 (SPN994039_17390)	-	1761080..1761721 (-)	642	WP_000565531.1	ABC transporter ATP-binding protein	-
SPN994039_RS09495 (SPN994039_17400)	-	1761723..1763753 (-)	2031	WP_000825263.1	bacteriocin-associated integral membrane family protein	-
SPN994039_RS09500 (SPN994039_17410)	-	1763830..1764126 (-)	297	WP_000815394.1	lactococcin 972 family bacteriocin	-
SPN994039_RS09505 (SPN994039_17420)	comR	1764446..1765345 (-)	900	WP_000904867.1	helix-turn-helix domain-containing protein	Regulator
SPN994039_RS09510 (SPN994039_17430)	rnmV	1765417..1765977 (-)	561	WP_000664448.1	ribonuclease M5	-
SPN994039_RS09515 (SPN994039_17440)	-	1765977..1766750 (-)	774	WP_000575607.1	TatD family hydrolase	-
SPN994039_RS09520 (SPN994039_17450)	-	1767056..1767733 (-)	678	WP_219338615.1	DUF1542 domain-containing protein	-
SPN994039_RS09525 (SPN994039_17460)	rpmH	1767972..1768106 (-)	135	WP_000831906.1	50S ribosomal protein L34	-
SPN994039_RS09530 (SPN994039_17470)	-	1768251..1769465 (-)	1215	WP_000666469.1	pyridoxal phosphate-dependent aminotransferase	-
SPN994039_RS09535 (SPN994039_17480)	-	1769621..1769914 (-)	294	WP_000977365.1	hypothetical protein	-

Sequence

Protein

• Length: 299 a.a.
• Molecular weight: 35191.04 Da
• Isoelectric Point: 5.0703

>NTDB_id=47853 SPN994039_RS09505 WP_000904867.1 1764446..1765345(-) (comR) [Streptococcus pneumoniae SPN994039]
MLIGQKIKEIRIEKGISRPDFCGDEQGLTVRQLSRIESGASQPSLPKLAYIARRLGVPVYSLMPDFSALPSAYLELKYQI
LREPIYGKEEEYDKKEACLEEIYKTYFDNLPKEEQLACEVLQACLDTSRTRRPEYAELILEEHMPQIIEKEAYSINDMLL
IRLFFYQMLIRKDLAKFINQIEKLMLFLLEQKKVTQIENYFIIRDTLISGMCCLEKVGVTDCFNDYLSCLQEIMDKTQDY
QKKPLVFMFLWKQALRVERDFSLAESFYQSSKTFAKLIGDGFLVKKLTEEWQEDVKKYL

Nucleotide

• Length: 900 bp

>NTDB_id=47853 SPN994039_RS09505 WP_000904867.1 1764446..1765345(-) (comR) [Streptococcus pneumoniae SPN994039]
ATGTTAATTGGTCAAAAAATTAAAGAGATTCGGATAGAAAAAGGAATTAGTCGTCCAGATTTTTGTGGAGATGAGCAAGG
ACTGACAGTTCGTCAACTGTCGCGAATTGAAAGTGGAGCTTCGCAACCGAGTTTGCCCAAGTTAGCCTATATTGCTCGCC
GGCTAGGAGTTCCAGTTTATAGCCTTATGCCGGATTTTTCAGCTCTTCCTTCTGCTTATTTAGAATTGAAATACCAGATT
TTACGTGAACCAATCTATGGTAAAGAAGAGGAGTACGATAAGAAGGAAGCGTGTTTGGAAGAGATTTATAAAACATACTT
TGATAATCTTCCTAAAGAAGAACAATTAGCATGTGAAGTATTGCAGGCGTGTTTGGATACTTCTAGAACTAGAAGGCCTG
AATATGCAGAGTTAATACTTGAGGAACATATGCCTCAGATTATAGAAAAAGAAGCTTATTCAATAAATGATATGTTGTTG
ATTCGTTTGTTTTTTTATCAAATGCTCATTAGAAAAGATCTTGCCAAATTTATAAATCAAATCGAAAAGCTAATGCTCTT
TCTTTTGGAACAGAAGAAGGTAACTCAAATAGAGAATTACTTTATAATTAGAGATACTCTTATTTCAGGAATGTGTTGTC
TTGAAAAGGTAGGAGTAACTGATTGTTTTAATGATTATCTATCTTGTTTACAAGAAATTATGGATAAAACTCAAGATTAT
CAAAAGAAACCTCTTGTATTTATGTTTTTGTGGAAGCAAGCATTAAGAGTAGAAAGAGATTTTAGTTTAGCTGAATCATT
TTATCAGTCTTCTAAAACATTTGCGAAGCTAATTGGAGATGGATTTCTAGTAAAGAAATTGACAGAGGAATGGCAAGAGG
ATGTCAAAAAATATTTATAA

Domains

Predicted by InterProScan.

• Helix-turn-helix (HTH_3) (7-59)

• ComR tetratricopeptide (ComR_TPR) (70-291)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR	Streptococcus mutans UA159	37.755	98.328	0.371
comR	Streptococcus suis P1/7	37.801	97.324	0.368
comR	Streptococcus suis 05ZYH33	37.801	97.324	0.368