Detailed information    

insolico Bioinformatically predicted

Overview

Name   hexB   Type   Machinery gene
Locus tag   J1N58_RS00365 Genome accession   NZ_CP071697
Coordinates   70651..72588 (+) Length   645 a.a.
NCBI ID   WP_207560404.1    Uniprot ID   -
Organism   Streptococcus suis strain 1112S     
Function   DNA mismatch repair (predicted from homology)   
Homologous recombination

Genomic Context

Location: 65651..77588
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J1N58_RS00345 (J1N58_00345) tnpA 65778..66272 (+) 495 Protein_50 IS200/IS605 family transposase -
  J1N58_RS00350 (J1N58_00350) comR 66482..67381 (+) 900 WP_024377696.1 helix-turn-helix domain-containing protein Regulator
  J1N58_RS00355 (J1N58_00355) - 67599..68819 (+) 1221 WP_207560402.1 folylpolyglutamate synthase/dihydrofolate synthase family protein -
  J1N58_RS00360 (J1N58_00360) - 69010..70533 (+) 1524 WP_207560403.1 quinol oxidase -
  J1N58_RS00365 (J1N58_00365) hexB 70651..72588 (+) 1938 WP_207560404.1 DNA mismatch repair endonuclease MutL Machinery gene
  J1N58_RS00370 (J1N58_00370) ruvA 72627..73217 (+) 591 WP_024406764.1 Holliday junction branch migration protein RuvA Machinery gene
  J1N58_RS00375 (J1N58_00375) - 73470..74039 (+) 570 WP_012774893.1 DNA-3-methyladenine glycosylase I -
  J1N58_RS00380 (J1N58_00380) cinA 74076..75257 (+) 1182 WP_207560405.1 competence/damage-inducible protein A Machinery gene
  J1N58_RS00385 (J1N58_00385) recA 75309..76460 (+) 1152 WP_172063701.1 recombinase RecA Machinery gene
  J1N58_RS00390 (J1N58_00390) spx 76620..77018 (+) 399 WP_004195475.1 transcriptional regulator Spx -
  J1N58_RS00395 (J1N58_00395) - 77125..77391 (+) 267 WP_004195477.1 IreB family regulatory phosphoprotein -

Sequence

Protein


Download         Length: 645 a.a.        Molecular weight: 72919.10 Da        Isoelectric Point: 5.1152

>NTDB_id=478330 J1N58_RS00365 WP_207560404.1 70651..72588(+) (hexB) [Streptococcus suis strain 1112S]
MSHIIELPEILANQIAAGEVIERPASVVKELVENSIDAGASQIEISVEEAGLKIIQITDNGEGIAPDEVALALRRHATSK
IKNQSDLFRIRTLGFRGEALPSIASVSHMIIETATADSAHGLHLEAKGGVIEKEEPVSRPVGTQITVSDLFYNTPARLKY
VRSQQAELSHIVDIVNRLSLAHPEIAFALVNEGRELIRTAGTGKLRQAISGIYGIASAKKMVEIEAEDLDFQISGYVSLP
ELTRANRNYISIFINGRYIKNFLLNRAILEGYGSKLMVGRFPLAVISIEIDPYLADVNVHPTKQEVRISKEKELMTLIRE
AISQALKEQDLIPDALENLAQSSTRPKVKAEQGTLPLREPKIYYDTIKQDFFLKPDVVAEDVKPLEEDRQEIVESPVENK
PTSVQFAERQSVESEDQEHPNLSAKELAKLADKLDREETSTFPELEYFGQMHGTYLFAQGKTGLYIIDQHAAQERVKYEY
YREKIGQVDNSAQQLLVPYIFEFPQNDALDLVHKMDALRQVGVNLEEYGANQFILREHPIWMKEEEIESGIYEMCDMLLL
TDQVSIKQYRAELAIMMSCKRSIKANHALDDYSARDLLRQLSYCQNPYNCPHGRPVLVHFSKSDMEKMFRRIQENHTSLR
ELGKY

Nucleotide


Download         Length: 1938 bp        

>NTDB_id=478330 J1N58_RS00365 WP_207560404.1 70651..72588(+) (hexB) [Streptococcus suis strain 1112S]
ATGTCACATATTATTGAACTACCAGAAATACTAGCCAACCAGATTGCTGCTGGTGAGGTCATTGAGCGACCAGCCAGTGT
GGTTAAGGAGTTGGTGGAAAATTCCATTGACGCAGGGGCTAGTCAGATTGAAATTAGTGTTGAAGAGGCTGGCCTTAAAA
TAATTCAAATTACGGATAACGGTGAGGGAATTGCCCCTGATGAAGTAGCGCTTGCCCTCCGCCGTCACGCTACCAGTAAG
ATAAAAAATCAATCGGATTTGTTTCGTATTCGCACCCTCGGTTTTCGTGGAGAAGCTCTGCCTTCCATTGCTTCTGTCAG
TCATATGATCATTGAGACAGCTACGGCAGACTCTGCACACGGACTTCATTTGGAGGCCAAAGGTGGTGTCATCGAGAAAG
AGGAGCCAGTTAGTCGTCCAGTTGGTACGCAGATTACTGTTTCGGATTTATTTTACAATACCCCTGCTCGTCTCAAATAC
GTTCGCAGTCAACAGGCTGAATTATCACATATTGTTGATATTGTAAATCGATTGAGTCTAGCTCATCCGGAAATAGCCTT
TGCCTTAGTAAACGAAGGACGAGAATTAATTAGAACTGCAGGGACAGGGAAACTTCGTCAGGCAATTTCAGGGATTTATG
GGATTGCTTCTGCCAAAAAAATGGTTGAAATTGAGGCAGAAGATCTGGATTTTCAGATTTCAGGTTACGTCTCCTTGCCA
GAGTTGACTCGCGCCAACCGCAACTACATTTCCATTTTCATCAACGGTCGCTATATCAAGAATTTTTTGCTGAATCGAGC
GATTTTGGAAGGTTACGGCAGTAAGTTGATGGTTGGACGCTTTCCATTGGCAGTCATTTCTATAGAAATTGATCCCTATC
TTGCTGATGTCAATGTGCATCCGACCAAGCAGGAAGTTCGCATCTCCAAGGAAAAAGAACTCATGACCTTGATTCGAGAG
GCGATTAGTCAAGCGCTTAAAGAGCAGGACTTGATACCAGATGCTCTTGAGAATTTAGCTCAGTCAAGTACTCGACCAAA
AGTAAAAGCAGAGCAAGGCACCTTACCACTCAGAGAGCCAAAAATCTATTATGATACGATTAAGCAAGACTTCTTCTTAA
AACCAGACGTGGTCGCTGAGGATGTCAAACCTCTCGAAGAGGATAGGCAAGAGATTGTTGAGTCGCCTGTCGAAAATAAA
CCTACATCTGTTCAATTTGCAGAACGTCAATCGGTGGAATCAGAAGATCAGGAGCATCCTAATCTAAGCGCAAAAGAATT
GGCAAAACTGGCAGATAAATTAGACCGGGAGGAAACATCGACATTTCCAGAGTTAGAATATTTTGGTCAAATGCATGGGA
CGTATTTATTTGCGCAAGGCAAGACAGGACTTTATATCATTGACCAGCATGCCGCACAAGAGAGGGTCAAATACGAATAC
TACCGTGAGAAAATTGGACAGGTTGACAATTCGGCTCAACAGTTATTGGTGCCGTATATTTTTGAATTTCCGCAGAATGA
TGCCCTTGACCTCGTCCACAAAATGGATGCCCTTCGTCAAGTAGGTGTCAACTTAGAAGAATATGGAGCTAATCAATTTA
TTCTGCGTGAACATCCTATTTGGATGAAGGAAGAGGAGATTGAGTCTGGCATTTATGAGATGTGCGATATGTTGCTCTTG
ACGGATCAGGTGTCAATCAAGCAGTATCGGGCAGAACTGGCTATCATGATGTCTTGTAAACGGTCAATCAAGGCCAACCA
TGCTTTGGATGATTATTCGGCGCGTGATTTATTGAGACAATTGTCTTACTGCCAAAATCCCTATAACTGCCCGCACGGTC
GTCCAGTCTTAGTACATTTTAGCAAATCGGATATGGAAAAAATGTTCCGTCGCATTCAAGAAAATCACACGAGTTTGCGA
GAGTTGGGCAAGTATTAA

Domains

Predicted by InterProScan.

DNA mismatch repair protein, C-terminal domain (DNA_mis_repair)

(210-326)

MutL C terminal dimerisation domain (MutL_C)

(447-589)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c_3)

(25-124)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  hexB Streptococcus pneumoniae R6

72.769

100

0.733