Detailed information    

insolico Bioinformatically predicted

Overview

Name   braR   Type   Regulator
Locus tag   SPN994039_RS07680 Genome accession   NC_021005
Coordinates   1442813..1443490 (-) Length   225 a.a.
NCBI ID   WP_000548991.1    Uniprot ID   A0A501PEF7
Organism   Streptococcus pneumoniae SPN994039     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 1437813..1448490
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  SPN994039_RS07655 (SPN994039_14170) - 1437974..1438603 (-) 630 WP_000762092.1 NAD(P)-dependent oxidoreductase -
  SPN994039_RS07660 (SPN994039_14180) - 1438842..1439216 (+) 375 WP_001252470.1 hypothetical protein -
  SPN994039_RS07665 (SPN994039_14190) - 1439473..1439796 (+) 324 WP_000422779.1 MazG-like protein -
  SPN994039_RS07670 (SPN994039_14200) thrS 1439854..1441797 (+) 1944 WP_000608354.1 threonine--tRNA ligase -
  SPN994039_RS07675 (SPN994039_14210) - 1441846..1442820 (-) 975 WP_000887971.1 sensor histidine kinase -
  SPN994039_RS07680 (SPN994039_14220) braR 1442813..1443490 (-) 678 WP_000548991.1 response regulator transcription factor Regulator
  SPN994039_RS07685 (SPN994039_14230) - 1443646..1444719 (+) 1074 WP_001273823.1 DUF2974 domain-containing protein -
  SPN994039_RS07690 - 1444810..1445112 (-) 303 WP_000281609.1 hypothetical protein -
  SPN994039_RS07695 (SPN994039_14240) - 1445180..1445617 (-) 438 WP_001166786.1 Rrf2 family transcriptional regulator -
  SPN994039_RS07700 (SPN994039_14250) - 1445693..1446534 (-) 842 Protein_1489 metallophosphoesterase family protein -
  SPN994039_RS07705 (SPN994039_14260) - 1446646..1447296 (+) 651 WP_000188505.1 metal-dependent transcriptional regulator -
  SPN994039_RS07715 (SPN994039_14270) - 1447475..1448152 (+) 678 WP_000260189.1 nicotinamide mononucleotide transporter -

Sequence

Protein


Download         Length: 225 a.a.        Molecular weight: 25936.11 Da        Isoelectric Point: 5.1362

>NTDB_id=47831 SPN994039_RS07680 WP_000548991.1 1442813..1443490(-) (braR) [Streptococcus pneumoniae SPN994039]
MHKILLVEDDQVIRQQVGKMLSEWGFEVVLVEDFMEVLSLFVQSEPHLVLMDIGLPLFNGYHWCQEIRKISKVPIMFLSS
RDQAMDIVMAINMGADDFVTKPFDQQVLLAKVQGLLRRSYEFGRDESLLEYAGVILNTKSMDLHYQGQVLNLTKNEFQIL
RVLFEHAGNIVARDDLMRELWNSDFFIDDNTLSVNVARLRKKLEEQGLVGFIETKKGIGYGLKHA

Nucleotide


Download         Length: 678 bp        

>NTDB_id=47831 SPN994039_RS07680 WP_000548991.1 1442813..1443490(-) (braR) [Streptococcus pneumoniae SPN994039]
ATGCACAAGATTTTATTAGTGGAAGATGATCAGGTCATTCGTCAACAGGTTGGGAAAATGCTCTCTGAATGGGGATTTGA
AGTGGTCCTGGTAGAAGACTTTATGGAAGTTTTGAGTCTATTTGTTCAGTCGGAACCTCATCTGGTCCTCATGGATATTG
GTTTGCCCTTGTTTAATGGTTATCACTGGTGTCAGGAAATCCGCAAGATTTCCAAGGTACCTATCATGTTTCTTTCTTCG
AGAGACCAGGCTATGGATATTGTCATGGCAATCAATATGGGAGCGGATGACTTTGTGACCAAGCCTTTTGACCAGCAGGT
TCTTTTAGCCAAGGTTCAGGGCTTGTTGCGTCGTTCCTATGAGTTTGGGCGTGATGAGAGTTTGCTGGAATATGCTGGTG
TTATCCTCAATACCAAATCCATGGATTTACATTATCAAGGGCAAGTCTTGAATTTGACCAAGAATGAATTCCAGATTTTA
CGCGTGTTGTTTGAGCATGCAGGCAACATCGTAGCACGTGACGACCTGATGCGAGAACTTTGGAACAGTGACTTTTTCAT
TGATGATAATACCCTCTCTGTCAATGTGGCTCGTTTGCGTAAAAAGTTGGAGGAGCAGGGATTGGTAGGATTTATCGAGA
CCAAGAAAGGAATAGGGTACGGATTGAAGCATGCTTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-112)

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(147-221)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A501PEF7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  braR Staphylococcus aureus N315

49.083

96.889

0.476
  vicR Streptococcus mutans UA159

35.319

100

0.369

Multiple sequence alignment