Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilC   Type   Machinery gene
Locus tag   IAE60_RS18375 Genome accession   NZ_CP060731
Coordinates   3915087..3916343 (+) Length   418 a.a.
NCBI ID   WP_187573333.1    Uniprot ID   A0A7G9TCJ8
Organism   Pseudoxanthomonas mexicana strain GTZY2     
Function   assembly of type IV pilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 3910087..3921343
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  IAE60_RS18365 (IAE60_18365) - 3911027..3912976 (+) 1950 WP_187573331.1 hypothetical protein -
  IAE60_RS18370 (IAE60_18370) pilB 3913127..3914863 (+) 1737 WP_187573332.1 type IV-A pilus assembly ATPase PilB Machinery gene
  IAE60_RS18375 (IAE60_18375) pilC 3915087..3916343 (+) 1257 WP_187573333.1 type II secretion system F family protein Machinery gene
  IAE60_RS18380 (IAE60_18380) pilD 3916353..3917216 (+) 864 WP_187573334.1 A24 family peptidase Machinery gene
  IAE60_RS18385 (IAE60_18385) coaE 3917250..3917867 (+) 618 WP_187573335.1 dephospho-CoA kinase -
  IAE60_RS18390 (IAE60_18390) - 3918014..3918439 (-) 426 WP_244966612.1 transposase -
  IAE60_RS18395 (IAE60_18395) - 3918818..3919768 (-) 951 WP_187573337.1 Nudix family hydrolase -

Sequence

Protein


Download         Length: 418 a.a.        Molecular weight: 45874.18 Da        Isoelectric Point: 10.2197

>NTDB_id=478155 IAE60_RS18375 WP_187573333.1 3915087..3916343(+) (pilC) [Pseudoxanthomonas mexicana strain GTZY2]
MAVTRSAVKKAPAPVRENPLNLFVWEGTDKRGVKMKGEQSSKNANFLRAELRKQGITPTVVKVKPKPLFGSAGKPVTPKE
IAFFSRQLATMMKSGVPIVSALEIIEGGQKNVRMKKLVENIRYDIESGSSLSEAISKYPVQFDELYRNLVRAGESAGVLE
TVLDTIASYKENIEALKGKIKKALFYPAVVIAVALLVSAILLIFVVPQFEAVFKQFGADLPAFTKIIVGASRFMVSNWYI
VFGAVFAAIFGFIFFKKRSLAFQHFLDRVILKVPVIGQIMHNSAIARFSRTLAVTFKAGVPLVEALDTVAGATGNTVYEK
AVHRVRDDVSVGYPLNMSMKQVNLFPHMVIQMTSIGEEAGALDAMLFKVAEYYEQEVNNAVDALSSLIEPFIMIFIGGVI
GAMVVGMYLPIFKLAATM

Nucleotide


Download         Length: 1257 bp        

>NTDB_id=478155 IAE60_RS18375 WP_187573333.1 3915087..3916343(+) (pilC) [Pseudoxanthomonas mexicana strain GTZY2]
ATGGCCGTCACTCGTTCCGCCGTCAAGAAAGCGCCCGCGCCCGTCCGCGAGAACCCGCTGAACCTGTTCGTCTGGGAAGG
CACCGACAAGCGCGGCGTCAAGATGAAGGGCGAGCAGTCGTCCAAGAACGCCAACTTCCTGCGCGCGGAGCTGCGCAAGC
AGGGCATCACCCCGACCGTGGTGAAGGTGAAGCCCAAGCCGCTGTTCGGCTCGGCGGGCAAGCCGGTGACGCCAAAGGAG
ATCGCGTTCTTCAGTCGCCAGCTGGCGACGATGATGAAGTCCGGCGTGCCGATCGTCAGCGCGCTGGAGATCATCGAGGG
CGGGCAGAAGAACGTCCGCATGAAAAAGCTGGTCGAGAACATCCGCTACGACATCGAAAGCGGCTCCTCTCTGTCCGAAG
CCATCAGCAAGTACCCGGTGCAGTTCGACGAGCTGTACCGCAACCTAGTCCGCGCCGGTGAAAGCGCGGGCGTGCTGGAA
ACCGTGCTGGACACCATCGCCAGCTACAAGGAAAACATCGAGGCCCTCAAGGGCAAGATCAAGAAGGCGCTGTTCTATCC
GGCCGTGGTGATCGCGGTCGCCCTTCTGGTCAGCGCCATCCTGCTCATCTTCGTGGTGCCGCAGTTCGAGGCGGTGTTCA
AGCAGTTCGGCGCCGACCTGCCGGCATTCACCAAGATCATCGTGGGTGCCTCGCGCTTCATGGTGTCGAACTGGTACATC
GTGTTCGGCGCCGTCTTCGCCGCCATCTTCGGCTTCATCTTCTTCAAGAAGCGCTCGCTGGCGTTCCAGCACTTCCTCGA
CCGCGTGATCCTGAAAGTCCCGGTGATCGGGCAGATCATGCACAACTCGGCCATCGCGCGTTTCTCGCGGACGCTGGCGG
TGACCTTCAAGGCCGGCGTGCCGCTGGTGGAGGCACTGGACACCGTCGCCGGTGCGACCGGCAACACGGTGTACGAAAAA
GCCGTGCATCGCGTGCGCGATGACGTGTCGGTGGGCTATCCGCTGAACATGTCCATGAAGCAGGTCAACCTGTTCCCGCA
CATGGTCATCCAGATGACCTCCATCGGCGAAGAGGCGGGCGCGCTGGACGCCATGCTGTTCAAGGTCGCGGAGTACTACG
AGCAGGAGGTGAACAACGCGGTGGATGCGCTGTCCAGCCTGATCGAGCCCTTCATCATGATCTTCATCGGCGGCGTGATC
GGCGCGATGGTGGTCGGCATGTACCTGCCCATCTTCAAGCTTGCCGCGACGATGTAA

Domains

Predicted by InterproScan.

Type II secretion system (T2SS), protein F (T2SSF)

(84-207)

Type II secretion system (T2SS), protein F (T2SSF)

(288-410)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A7G9TCJ8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilC Legionella pneumophila strain ERS1305867

54.02

95.215

0.514
  pilC Pseudomonas stutzeri DSM 10701

50.758

94.737

0.481
  pilC Acinetobacter baumannii D1279779

50.127

94.498

0.474
  pilC Acinetobacter baylyi ADP1

50

94.737

0.474
  pilG Neisseria gonorrhoeae MS11

44.051

94.498

0.416
  pilG Neisseria meningitidis 44/76-A

43.797

94.498

0.414
  pilC Vibrio cholerae strain A1552

40.25

95.694

0.385
  pilC Vibrio campbellii strain DS40M4

38.929

98.325

0.383