Detailed information    

insolico Bioinformatically predicted

Overview

Name   pilH   Type   Machinery gene
Locus tag   NMBB_RS04765 Genome accession   NC_017505
Coordinates   904509..905177 (+) Length   222 a.a.
NCBI ID   WP_014575282.1    Uniprot ID   -
Organism   Neisseria meningitidis alpha710     
Function   type IV pilus (predicted from homology)   
DNA binding and uptake

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Genomic island 905818..920435 904509..905177 flank 641


Gene organization within MGE regions


Location: 904509..920435
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  NMBB_RS04765 (NMBB_0992) pilH 904509..905177 (+) 669 WP_014575282.1 Tfp pilus assembly protein FimT/FimU Machinery gene
  NMBB_RS04770 (NMBB_0993) pilV 905207..905821 (+) 615 WP_002222656.1 type IV pilus modification protein PilV Machinery gene
  NMBB_RS04775 (NMBB_0994) pilJ 905818..906756 (+) 939 WP_002222655.1 PilW family protein Machinery gene
  NMBB_RS04780 (NMBB_0995) pilK 906735..907331 (+) 597 WP_002222654.1 pilus assembly protein Machinery gene
  NMBB_RS04785 (NMBB_0996) pilX 907336..907809 (+) 474 WP_021438285.1 PilX family type IV pilin Machinery gene
  NMBB_RS04790 (NMBB_0998) - 908412..908837 (-) 426 Protein_894 AzlC family ABC transporter permease -
  NMBB_RS04795 (NMBB_0999) dut 908982..909434 (+) 453 WP_002222651.1 dUTP diphosphatase -
  NMBB_RS04800 (NMBB_1000) dapC 909510..910697 (+) 1188 WP_002222650.1 succinyldiaminopimelate transaminase -
  NMBB_RS04805 (NMBB_1001) yaaA 910959..911738 (+) 780 WP_002222649.1 peroxide stress protein YaaA -
  NMBB_RS04820 (NMBB_1003A) - 912270..913468 (+) 1199 Protein_898 integrase arm-type DNA-binding domain-containing protein -
  NMBB_RS04825 (NMBB_1004) - 913623..914003 (+) 381 WP_002220683.1 type II toxin-antitoxin system PemK/MazF family toxin -
  NMBB_RS04835 (NMBB_1007A) - 914551..914907 (+) 357 WP_002223441.1 DUF4760 domain-containing protein -
  NMBB_RS04840 (NMBB_1010) - 915776..916693 (+) 918 WP_002219437.1 KilA-N domain-containing protein -
  NMBB_RS04845 (NMBB_1011) - 916751..916960 (-) 210 WP_002220687.1 hypothetical protein -
  NMBB_RS12480 - 916957..917097 (-) 141 WP_002223442.1 hypothetical protein -
  NMBB_RS04850 (NMBB_1011A) - 917097..917288 (-) 192 WP_002219435.1 type ISP restriction/modification enzyme -
  NMBB_RS04855 (NMBB_1012) - 917291..917584 (-) 294 WP_002220689.1 hypothetical protein -
  NMBB_RS04860 (NMBB_1013) - 917581..917841 (-) 261 WP_002223443.1 hypothetical protein -
  NMBB_RS04865 (NMBB_1014) - 917876..918091 (-) 216 WP_002219434.1 hypothetical protein -
  NMBB_RS04870 (NMBB_1015) - 918161..919015 (-) 855 WP_002219433.1 YfdQ family protein -
  NMBB_RS04875 (NMBB_1016) - 919040..919399 (-) 360 WP_002219432.1 hypothetical protein -
  NMBB_RS04880 (NMBB_1017) - 919467..919667 (-) 201 WP_002219431.1 hypothetical protein -
  NMBB_RS04885 (NMBB_1018) - 919911..920336 (-) 426 WP_002219430.1 hypothetical protein -

Sequence

Protein


Download         Length: 222 a.a.        Molecular weight: 24795.30 Da        Isoelectric Point: 9.5822

>NTDB_id=47788 NMBB_RS04765 WP_014575282.1 904509..905177(+) (pilH) [Neisseria meningitidis alpha710]
MCTRKQQGFTLTELLIVMVIAAIMAMIALPNMSQWIASRRIASHAERIANLLRFSRGEAVRLNLPVYICPVQVKKDGTPN
NKCDSGKKGQGMLAFGDKNGNKGYDNDTADVLLRSVVLNDDINDKRINYAFNHIAFGQTQPTADRVVWTFNQNGTFGYST
NQDLTNTSKFVYSDGYIQIVLTDARAVSDADKKFRSAVVLIDSSGRVEVCPRNDRRTVCQYK

Nucleotide


Download         Length: 669 bp        

>NTDB_id=47788 NMBB_RS04765 WP_014575282.1 904509..905177(+) (pilH) [Neisseria meningitidis alpha710]
ATGTGTACACGAAAACAACAAGGTTTCACGCTAACAGAGCTGCTCATCGTGATGGTCATTGCAGCCATTATGGCGATGAT
AGCCCTCCCCAATATGAGCCAATGGATTGCATCCCGCCGCATTGCCAGTCACGCGGAGCGGATTGCCAACCTTTTGCGTT
TCTCCAGGGGCGAAGCCGTCCGGCTCAATCTCCCTGTCTATATCTGTCCTGTTCAAGTTAAAAAAGACGGTACGCCCAAC
AATAAATGTGACTCCGGCAAGAAGGGGCAGGGAATGTTGGCTTTCGGCGACAAAAACGGCAATAAGGGATATGACAATGA
TACGGCGGATGTTCTTCTCCGCAGTGTGGTATTGAATGATGATATCAATGATAAGCGGATTAATTATGCCTTCAACCATA
TCGCTTTCGGTCAGACTCAGCCGACCGCTGACCGTGTAGTTTGGACATTCAATCAAAACGGGACGTTCGGTTATTCTACC
AATCAGGATCTCACGAATACTTCCAAATTTGTTTACTCCGACGGTTATATCCAAATCGTGCTGACAGATGCGAGAGCAGT
TTCAGATGCCGATAAGAAATTCCGTTCGGCGGTGGTTTTGATTGACAGCAGCGGCAGGGTTGAGGTTTGTCCTAGAAACG
ATAGGCGTACCGTATGCCAATATAAATGA

Domains

Predicted by InterproScan.

Prokaryotic N-terminal methylation motif (N_methyl)

(4-29)

Type II transport protein GspH (GspH)

(44-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  pilH Neisseria gonorrhoeae MS11

85.068

99.55

0.847

Multiple sequence alignment