Detailed information    

insolico Bioinformatically predicted

Overview

Name   eeP   Type   Regulator
Locus tag   H7789_RS08240 Genome accession   NZ_CP060646
Coordinates   1670585..1671844 (-) Length   419 a.a.
NCBI ID   WP_002993670.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain TSPY1026     
Function   processing of ComS (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1615912..1685158 1670585..1671844 within 0


Gene organization within MGE regions


Location: 1615912..1685158
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7789_RS07960 (H7789_07950) - 1615934..1616707 (+) 774 WP_002982738.1 DeoR/GlpR family DNA-binding transcription regulator -
  H7789_RS07965 (H7789_07955) - 1617368..1617655 (+) 288 WP_002988079.1 DNA-damage-inducible protein J -
  H7789_RS07970 (H7789_07960) - 1617645..1617980 (+) 336 WP_002982731.1 type II toxin-antitoxin system RelE/ParE family toxin -
  H7789_RS07975 - 1618078..1619065 (+) 988 Protein_1521 tyrosine-type recombinase/integrase -
  H7789_RS07980 - 1619433..1619519 (-) 87 WP_227874724.1 type II toxin-antitoxin system RelE/ParE family toxin -
  H7789_RS07985 (H7789_07975) - 1619519..1619743 (-) 225 WP_227874722.1 hypothetical protein -
  H7789_RS07990 (H7789_07980) - 1620118..1623012 (+) 2895 WP_136096249.1 DNA methyltransferase -
  H7789_RS07995 (H7789_07985) - 1623027..1625411 (-) 2385 WP_115230700.1 restriction endonuclease -
  H7789_RS08000 (H7789_07990) - 1625395..1625889 (-) 495 WP_115230701.1 hypothetical protein -
  H7789_RS08005 (H7789_07995) - 1626086..1626763 (-) 678 Protein_1527 helix-turn-helix domain-containing protein -
  H7789_RS08010 (H7789_08000) - 1626766..1627629 (-) 864 WP_115230702.1 ImmA/IrrE family metallo-endopeptidase -
  H7789_RS08015 (H7789_08005) - 1627857..1628990 (-) 1134 WP_136271291.1 ISAs1-like element IS1548 family transposase -
  H7789_RS08020 (H7789_08010) - 1629442..1629690 (+) 249 WP_085634384.1 hypothetical protein -
  H7789_RS08025 (H7789_08015) - 1629728..1630024 (+) 297 WP_085634385.1 cytoplasmic protein -
  H7789_RS08030 (H7789_08020) - 1630043..1630498 (+) 456 WP_228628132.1 conjugal transfer protein -
  H7789_RS08035 (H7789_08025) - 1630514..1632193 (+) 1680 WP_228628134.1 FtsK/SpoIIIE domain-containing protein -
  H7789_RS08040 (H7789_08030) - 1632414..1633667 (+) 1254 Protein_1534 replication initiation factor domain-containing protein -
  H7789_RS08045 (H7789_08035) mazE 1633724..1634005 (+) 282 WP_017649870.1 type II toxin-antitoxin system PemI/MazE family antitoxin -
  H7789_RS08050 (H7789_08040) - 1633998..1634333 (+) 336 WP_227874721.1 type II toxin-antitoxin system RelE/ParE family toxin -
  H7789_RS08055 (H7789_08045) - 1634397..1634627 (+) 231 WP_085634389.1 hypothetical protein -
  H7789_RS08060 (H7789_08050) - 1634648..1635199 (+) 552 WP_115230708.1 conjugal transfer protein -
  H7789_RS08065 (H7789_08055) - 1635212..1636192 (+) 981 WP_136261201.1 conjugal transfer protein -
  H7789_RS08070 (H7789_08060) - 1636198..1636422 (+) 225 WP_115230710.1 hypothetical protein -
  H7789_RS08075 (H7789_08065) - 1636424..1636846 (+) 423 WP_085634393.1 conjugal transfer protein -
  H7789_RS08080 (H7789_08070) - 1636859..1639363 (+) 2505 Protein_1542 ATP-binding protein -
  H7789_RS08085 (H7789_08075) - 1639378..1641288 (+) 1911 WP_136273126.1 PT domain-containing protein -
  H7789_RS08090 (H7789_08080) - 1641275..1641502 (+) 228 WP_115230712.1 hypothetical protein -
  H7789_RS08095 (H7789_08085) - 1641521..1642633 (+) 1113 WP_136074294.1 phage tail tip lysozyme -
  H7789_RS08100 (H7789_08090) - 1642817..1643062 (+) 246 WP_115230714.1 helix-turn-helix domain-containing protein -
  H7789_RS08105 (H7789_08095) - 1643102..1644319 (+) 1218 WP_115230715.1 tyrosine-type recombinase/integrase -
  H7789_RS08110 (H7789_08100) rpsI 1644429..1644821 (-) 393 WP_002982716.1 30S ribosomal protein S9 -
  H7789_RS08115 (H7789_08105) rplM 1644842..1645288 (-) 447 WP_002982710.1 50S ribosomal protein L13 -
  H7789_RS08120 (H7789_08110) - 1645506..1645712 (-) 207 WP_136026367.1 helix-turn-helix transcriptional regulator -
  H7789_RS08125 (H7789_08115) - 1645709..1646407 (-) 699 WP_228628136.1 hypothetical protein -
  H7789_RS08130 (H7789_08120) - 1646543..1647403 (-) 861 WP_011529009.1 DegV family protein -
  H7789_RS08135 (H7789_08125) - 1647500..1648018 (-) 519 WP_011285178.1 NYN domain-containing protein -
  H7789_RS08140 (H7789_08130) rlmB 1648022..1648768 (-) 747 WP_010922667.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  H7789_RS08145 (H7789_08135) - 1648815..1649612 (-) 798 WP_136104975.1 hypothetical protein -
  H7789_RS08150 (H7789_08140) - 1649808..1650221 (-) 414 WP_002982672.1 Mini-ribonuclease 3 -
  H7789_RS08155 (H7789_08145) cysS 1650214..1651557 (-) 1344 WP_228628138.1 cysteine--tRNA ligase -
  H7789_RS08160 (H7789_08150) - 1651585..1651815 (-) 231 WP_023078901.1 hypothetical protein -
  H7789_RS08165 (H7789_08155) cysE 1652294..1652875 (-) 582 WP_002982658.1 serine O-acetyltransferase -
  H7789_RS08170 (H7789_08160) - 1652884..1653636 (-) 753 WP_136096589.1 SseB family protein -
  H7789_RS08175 (H7789_08165) pnp 1653629..1655761 (-) 2133 WP_228628140.1 polyribonucleotide nucleotidyltransferase -
  H7789_RS08180 (H7789_08170) - 1656042..1656773 (-) 732 WP_020905499.1 transaldolase -
  H7789_RS08185 (H7789_08175) - 1656783..1658162 (-) 1380 WP_002994557.1 PTS ascorbate transporter subunit IIC -
  H7789_RS08190 (H7789_08180) - 1658189..1658473 (-) 285 WP_002982644.1 PTS sugar transporter subunit IIB -
  H7789_RS08195 (H7789_08185) - 1658466..1660526 (-) 2061 WP_228628142.1 BglG family transcription antiterminator -
  H7789_RS08200 (H7789_08190) rpsO 1660879..1661148 (-) 270 WP_002982634.1 30S ribosomal protein S15 -
  H7789_RS08205 (H7789_08195) - 1661324..1661524 (-) 201 WP_002982630.1 hypothetical protein -
  H7789_RS08210 (H7789_08200) - 1661650..1661919 (+) 270 WP_002994564.1 transcriptional regulator -
  H7789_RS08215 (H7789_08205) def 1662021..1662635 (+) 615 WP_002982624.1 peptide deformylase -
  H7789_RS08220 (H7789_08210) - 1662669..1663211 (-) 543 WP_014407860.1 NADPH-dependent FMN reductase -
  H7789_RS08225 (H7789_08215) - 1663342..1663770 (-) 429 WP_002982615.1 MarR family winged helix-turn-helix transcriptional regulator -
  H7789_RS08230 (H7789_08220) - 1663880..1668277 (-) 4398 WP_228628144.1 PolC-type DNA polymerase III -
  H7789_RS08235 (H7789_08225) - 1668531..1670387 (-) 1857 WP_136099301.1 proline--tRNA ligase -
  H7789_RS08240 (H7789_08230) eeP 1670585..1671844 (-) 1260 WP_002993670.1 RIP metalloprotease RseP Regulator
  H7789_RS08245 (H7789_08235) - 1671917..1672711 (-) 795 WP_228628145.1 phosphatidate cytidylyltransferase -
  H7789_RS08250 (H7789_08240) - 1672724..1673473 (-) 750 WP_228628147.1 isoprenyl transferase -
  H7789_RS08255 (H7789_08245) yajC 1673692..1674051 (-) 360 WP_002982594.1 preprotein translocase subunit YajC -
  H7789_RS08260 (H7789_08250) - 1674167..1674541 (-) 375 WP_010922685.1 thioredoxin domain-containing protein -
  H7789_RS08265 (H7789_08255) - 1674657..1678154 (-) 3498 WP_228628149.1 pullulanase -
  H7789_RS08270 (H7789_08260) dexB 1678352..1679965 (-) 1614 WP_228628151.1 glucan 1,6-alpha-glucosidase DexB -
  H7789_RS08275 (H7789_08265) - 1680094..1681227 (-) 1134 WP_002993686.1 ABC transporter ATP-binding protein -
  H7789_RS08280 (H7789_08270) - 1681525..1682373 (-) 849 WP_323743820.1 PucR family transcriptional regulator -
  H7789_RS08285 (H7789_08275) ska 1682713..1684011 (+) 1299 WP_136261188.1 streptokinase -
  H7789_RS08290 (H7789_08280) dtd 1684109..1684552 (-) 444 WP_115225252.1 D-aminoacyl-tRNA deacylase -

Sequence

Protein


Download         Length: 419 a.a.        Molecular weight: 45718.48 Da        Isoelectric Point: 9.4314

>NTDB_id=477382 H7789_RS08240 WP_002993670.1 1670585..1671844(-) (eeP) [Streptococcus pyogenes strain TSPY1026]
MLGIITFIIIFGILVIVHEFGHFYFAKKSGILVREFAIGMGPKIFSHVDQGGTLYTLRMLPLGGYVRMAGWGDDKTEIKT
GTPASLTLNEQGFVKRINLSQSKLDPTSLPMHVTGYDLEDQLSITGLVLEETKTYKVAHDATIVEEDGTEIRIAPLDVQY
QNASIGGRLITNFAGPMNNFILGIVVFILLVFLQGGMPDFSSNHVRVQENGAAAKAGLRDNDQIVAINGYKVTSWNDLTE
AVNLATRDLGPSQTIKVTYKSHQRLKTVAVKPQKHAKTYTIGVKASLKTGFKDKLLGGLELAWSGAFTILNALKGLITGF
SLNKLGGPVAMYDMSNQAAQNGLESVLSLMAMLSINLGIFNLIPIPALDGGKILMNIIEAIRRKPIKQETEAYITLAGVA
IMVVLMIAVTWNDIMRVFF

Nucleotide


Download         Length: 1260 bp        

>NTDB_id=477382 H7789_RS08240 WP_002993670.1 1670585..1671844(-) (eeP) [Streptococcus pyogenes strain TSPY1026]
ATGTTAGGAATAATAACCTTTATTATTATTTTTGGTATTTTAGTGATTGTCCATGAATTTGGACATTTCTATTTTGCTAA
AAAATCAGGCATTCTAGTAAGAGAATTTGCCATTGGAATGGGCCCTAAAATTTTTTCTCATGTTGACCAAGGAGGAACTC
TTTATACCTTGAGGATGTTACCCTTGGGCGGTTATGTGCGAATGGCTGGTTGGGGTGATGACAAAACTGAGATCAAAACA
GGTACTCCAGCAAGTTTAACCCTTAATGAGCAAGGTTTTGTTAAGCGCATCAACTTGTCTCAAAGTAAGTTAGACCCAAC
GAGTCTCCCAATGCATGTTACAGGCTATGACTTAGAAGATCAGCTGAGTATTACTGGCTTGGTTTTAGAAGAAACCAAGA
CATATAAGGTCGCTCACGATGCTACTATTGTTGAAGAAGACGGTACTGAGATAAGAATTGCTCCGCTTGATGTTCAATAT
CAAAATGCTAGTATTGGCGGACGTTTAATCACCAATTTTGCAGGTCCCATGAATAATTTTATTTTAGGGATTGTGGTTTT
TATCCTCTTGGTCTTTTTACAAGGTGGGATGCCAGATTTTAGTAGCAATCATGTTCGTGTTCAAGAAAATGGAGCAGCAG
CTAAGGCTGGTCTTCGAGATAATGACCAAATTGTCGCAATTAATGGTTATAAGGTGACTAGCTGGAATGATCTCACTGAG
GCTGTAAACCTTGCAACACGGGATCTAGGCCCGTCACAGACCATTAAGGTCACCTACAAGTCACATCAGCGCTTAAAAAC
GGTGGCTGTGAAACCACAAAAGCATGCAAAGACATACACGATAGGAGTTAAGGCGAGTCTGAAAACAGGATTTAAGGATA
AGCTCTTAGGCGGTCTAGAATTAGCTTGGAGTGGGGCGTTTACTATTTTGAATGCTTTGAAAGGATTGATCACTGGCTTT
AGTCTCAATAAATTAGGTGGACCTGTTGCCATGTATGACATGTCCAATCAGGCTGCTCAAAACGGCTTAGAGTCAGTCTT
ATCTCTTATGGCAATGCTTTCGATCAATTTAGGGATCTTTAACCTGATTCCGATTCCTGCACTTGATGGGGGAAAAATCT
TGATGAATATCATTGAAGCCATTCGTCGCAAGCCTATCAAGCAAGAAACAGAGGCCTATATCACCCTAGCTGGGGTTGCT
ATCATGGTCGTATTGATGATTGCTGTGACATGGAATGATATCATGCGCGTCTTTTTCTAA

Domains

Predicted by InterproScan.

PDZ domain (PDZ_2)

(206-271)

Peptidase family M50 (Peptidase_M50)

(6-405)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  eeP Streptococcus thermophilus LMG 18311

68.571

100

0.687
  eeP Streptococcus thermophilus LMD-9

68.333

100

0.685