Detailed information    

insolico Bioinformatically predicted

Overview

Name   eeP   Type   Regulator
Locus tag   H7790_RS08420 Genome accession   NZ_CP060645
Coordinates   1694014..1695273 (-) Length   419 a.a.
NCBI ID   WP_011529024.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain TSPY1349     
Function   processing of ComS (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
ICE 1639370..1708615 1694014..1695273 within 0


Gene organization within MGE regions


Location: 1639370..1708615
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H7790_RS08145 (H7790_08165) - 1639392..1640165 (+) 774 WP_011285171.1 DeoR/GlpR family DNA-binding transcription regulator -
  H7790_RS08150 (H7790_08170) - 1640815..1641102 (+) 288 WP_002988079.1 DNA-damage-inducible protein J -
  H7790_RS08155 (H7790_08175) - 1641092..1641427 (+) 336 WP_009880846.1 type II toxin-antitoxin system RelE/ParE family toxin -
  H7790_RS08160 - 1641525..1642513 (+) 989 Protein_1576 tyrosine-type recombinase/integrase -
  H7790_RS09430 - 1642881..1642967 (-) 87 WP_227874724.1 type II toxin-antitoxin system RelE/ParE family toxin -
  H7790_RS09435 - 1642967..1643176 (-) 210 WP_281727034.1 hypothetical protein -
  H7790_RS08170 (H7790_08195) - 1643551..1646445 (+) 2895 WP_115230699.1 DNA methyltransferase -
  H7790_RS08175 (H7790_08200) - 1646460..1648844 (-) 2385 WP_115230700.1 restriction endonuclease -
  H7790_RS08180 (H7790_08205) - 1648828..1649292 (-) 465 WP_227874723.1 hypothetical protein -
  H7790_RS08185 (H7790_08210) - 1649519..1650196 (-) 678 Protein_1582 helix-turn-helix domain-containing protein -
  H7790_RS08190 (H7790_08215) - 1650199..1651062 (-) 864 WP_136073850.1 ImmA/IrrE family metallo-endopeptidase -
  H7790_RS08195 (H7790_08220) - 1651290..1652423 (-) 1134 WP_014635671.1 ISAs1-like element IS1548 family transposase -
  H7790_RS08200 (H7790_08225) - 1652874..1653122 (+) 249 WP_085634384.1 hypothetical protein -
  H7790_RS08205 (H7790_08230) - 1653160..1653456 (+) 297 WP_085634385.1 cytoplasmic protein -
  H7790_RS08210 (H7790_08235) - 1653475..1653930 (+) 456 WP_065736536.1 conjugal transfer protein -
  H7790_RS08215 (H7790_08240) - 1653946..1655625 (+) 1680 WP_115230705.1 FtsK/SpoIIIE domain-containing protein -
  H7790_RS08220 (H7790_08245) - 1655846..1657099 (+) 1254 WP_115230706.1 replication initiation factor domain-containing protein -
  H7790_RS08225 (H7790_08250) mazE 1657156..1657437 (+) 282 WP_017649870.1 type II toxin-antitoxin system PemI/MazE family antitoxin -
  H7790_RS08230 (H7790_08255) - 1657430..1657765 (+) 336 WP_227874721.1 type II toxin-antitoxin system RelE/ParE family toxin -
  H7790_RS08235 (H7790_08260) - 1657829..1658059 (+) 231 WP_115230707.1 hypothetical protein -
  H7790_RS08240 (H7790_08265) - 1658080..1658631 (+) 552 WP_115230708.1 conjugal transfer protein -
  H7790_RS08245 (H7790_08270) - 1658644..1659624 (+) 981 WP_115230709.1 conjugal transfer protein -
  H7790_RS08250 (H7790_08275) - 1659630..1659854 (+) 225 WP_115230710.1 hypothetical protein -
  H7790_RS08255 (H7790_08280) - 1659856..1660278 (+) 423 WP_085634393.1 conjugal transfer protein -
  H7790_RS08260 (H7790_08285) - 1660291..1662795 (+) 2505 Protein_1597 ATP-binding protein -
  H7790_RS08265 (H7790_08290) - 1662810..1664720 (+) 1911 WP_115230711.1 PT domain-containing protein -
  H7790_RS08270 (H7790_08295) - 1664707..1664934 (+) 228 WP_115230712.1 hypothetical protein -
  H7790_RS08275 (H7790_08300) - 1664953..1666065 (+) 1113 WP_115230713.1 phage tail tip lysozyme -
  H7790_RS08280 (H7790_08305) - 1666249..1666494 (+) 246 WP_115230714.1 helix-turn-helix domain-containing protein -
  H7790_RS08285 (H7790_08310) - 1666534..1667751 (+) 1218 WP_115230715.1 tyrosine-type recombinase/integrase -
  H7790_RS08290 (H7790_08315) rpsI 1667861..1668253 (-) 393 WP_002982716.1 30S ribosomal protein S9 -
  H7790_RS08295 (H7790_08320) rplM 1668274..1668720 (-) 447 WP_002982710.1 50S ribosomal protein L13 -
  H7790_RS08300 (H7790_08325) - 1668938..1669144 (-) 207 WP_002982695.1 helix-turn-helix transcriptional regulator -
  H7790_RS08305 (H7790_08330) - 1669141..1669839 (-) 699 WP_063632128.1 hypothetical protein -
  H7790_RS08310 (H7790_08335) - 1669975..1670835 (-) 861 WP_011529009.1 DegV family protein -
  H7790_RS08315 (H7790_08340) - 1670932..1671450 (-) 519 WP_011055010.1 NYN domain-containing protein -
  H7790_RS08320 (H7790_08345) rlmB 1671454..1672200 (-) 747 WP_010922667.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  H7790_RS08325 (H7790_08350) - 1672247..1673044 (-) 798 WP_063632129.1 hypothetical protein -
  H7790_RS08330 (H7790_08355) - 1673240..1673653 (-) 414 WP_011285181.1 Mini-ribonuclease 3 -
  H7790_RS08335 (H7790_08360) cysS 1673646..1674989 (-) 1344 WP_115230716.1 cysteine--tRNA ligase -
  H7790_RS08340 (H7790_08365) - 1675017..1675247 (-) 231 WP_010922670.1 hypothetical protein -
  H7790_RS08345 (H7790_08370) cysE 1675726..1676307 (-) 582 WP_010922671.1 serine O-acetyltransferase -
  H7790_RS08350 (H7790_08375) - 1676316..1677068 (-) 753 WP_032465246.1 SseB family protein -
  H7790_RS08355 (H7790_08380) pnp 1677061..1679193 (-) 2133 WP_115230717.1 polyribonucleotide nucleotidyltransferase -
  H7790_RS08360 (H7790_08385) - 1679473..1680204 (-) 732 WP_115230718.1 transaldolase -
  H7790_RS08365 (H7790_08390) - 1680214..1681593 (-) 1380 WP_002994557.1 PTS ascorbate transporter subunit IIC -
  H7790_RS08370 (H7790_08395) - 1681620..1681904 (-) 285 WP_002982644.1 PTS sugar transporter subunit IIB -
  H7790_RS08375 (H7790_08400) - 1681897..1683957 (-) 2061 WP_115230813.1 BglG family transcription antiterminator -
  H7790_RS08380 (H7790_08405) rpsO 1684309..1684578 (-) 270 WP_002982634.1 30S ribosomal protein S15 -
  H7790_RS08385 (H7790_08410) - 1684754..1684954 (-) 201 WP_011055018.1 hypothetical protein -
  H7790_RS08390 (H7790_08415) - 1685080..1685349 (+) 270 WP_002994564.1 transcriptional regulator -
  H7790_RS08395 (H7790_08420) def 1685449..1686063 (+) 615 WP_063629192.1 peptide deformylase -
  H7790_RS08400 (H7790_08425) - 1686097..1686639 (-) 543 WP_115230719.1 NADPH-dependent FMN reductase -
  H7790_RS08405 (H7790_08430) - 1686770..1687198 (-) 429 WP_002982615.1 MarR family winged helix-turn-helix transcriptional regulator -
  H7790_RS08410 (H7790_08435) - 1687308..1691705 (-) 4398 WP_115230720.1 PolC-type DNA polymerase III -
  H7790_RS08415 (H7790_08440) - 1691960..1693816 (-) 1857 WP_009880419.1 proline--tRNA ligase -
  H7790_RS08420 (H7790_08445) eeP 1694014..1695273 (-) 1260 WP_011529024.1 RIP metalloprotease RseP Regulator
  H7790_RS08425 (H7790_08450) - 1695346..1696140 (-) 795 WP_002982606.1 phosphatidate cytidylyltransferase -
  H7790_RS08430 (H7790_08455) - 1696153..1696902 (-) 750 WP_115230722.1 isoprenyl transferase -
  H7790_RS08435 (H7790_08460) yajC 1697120..1697485 (-) 366 WP_002988027.1 preprotein translocase subunit YajC -
  H7790_RS08440 (H7790_08465) - 1697601..1697948 (-) 348 WP_011529027.1 thioredoxin domain-containing protein -
  H7790_RS08445 (H7790_08470) - 1698090..1701587 (-) 3498 WP_136073837.1 pullulanase -
  H7790_RS08450 (H7790_08475) - 1701785..1703398 (-) 1614 WP_115230724.1 alpha-glucosidase -
  H7790_RS08455 (H7790_08480) - 1703527..1704660 (-) 1134 WP_002993686.1 ABC transporter ATP-binding protein -
  H7790_RS08460 (H7790_08485) - 1704958..1705806 (-) 849 WP_115230725.1 helix-turn-helix domain-containing protein -
  H7790_RS08465 (H7790_08490) ska 1706146..1707468 (+) 1323 WP_115230726.1 streptokinase -
  H7790_RS08470 (H7790_08495) dtd 1707566..1708009 (-) 444 WP_115230727.1 D-aminoacyl-tRNA deacylase -

Sequence

Protein


Download         Length: 419 a.a.        Molecular weight: 45749.49 Da        Isoelectric Point: 9.2387

>NTDB_id=477329 H7790_RS08420 WP_011529024.1 1694014..1695273(-) (eeP) [Streptococcus pyogenes strain TSPY1349]
MLGIITFIIIFGILVIVHEFGHFYFAKKSGILVREFAIGMGPKIFSHVDQGGTLYTLRMLPLGGYVRMAGWGDDKTEIKT
GTPASLTLNEQGFVKRINLSQSKLDPTSLPMHVTGYDLEDQLSITGLVLEETKTYKVAHDATIVEEDGTEIRIAPLDVQY
QNASIGGRLITNFAGPMNNFILGIVVFILLVFLQGGMPDFSSNHVRVQENGAAAKAGLRDNDQIVAINGYKVTSWNDLTE
AVDLATRDLGPSQTIKVTYKSHQRLKTVAVKPQKHAKTYTIGVKASLKTGFKDKLLGGLELAWSGAFTILNTLKGLITGF
SLNKLGGPVAMYDMSNQAAQNGLESVLSLMAMLSINLGIFNLIPIPALDGGKILMNIIEAIRRKPIKQETEAYITLAGVA
IMVVLMIAVTWNDIMRVFF

Nucleotide


Download         Length: 1260 bp        

>NTDB_id=477329 H7790_RS08420 WP_011529024.1 1694014..1695273(-) (eeP) [Streptococcus pyogenes strain TSPY1349]
ATGTTAGGAATAATAACCTTTATTATTATTTTTGGTATTTTAGTGATTGTCCATGAATTTGGACATTTCTATTTTGCTAA
AAAATCAGGCATTCTAGTAAGAGAATTTGCCATTGGAATGGGCCCTAAAATTTTTTCTCATGTTGACCAAGGAGGAACTC
TTTATACCTTGAGGATGTTACCCTTGGGCGGTTATGTGCGAATGGCTGGTTGGGGTGATGACAAAACTGAGATCAAAACA
GGTACTCCAGCAAGTTTAACCCTTAATGAGCAAGGTTTTGTTAAGCGCATCAACTTGTCTCAAAGTAAGTTAGACCCAAC
GAGTCTCCCAATGCATGTTACAGGCTATGACTTAGAAGATCAGCTGAGTATTACTGGCTTGGTTTTAGAAGAAACCAAGA
CATATAAGGTCGCTCACGATGCTACTATTGTTGAAGAAGACGGTACTGAGATAAGAATTGCTCCGCTTGATGTTCAATAT
CAAAATGCTAGTATTGGCGGACGTTTAATCACCAATTTTGCAGGTCCCATGAATAATTTTATTTTAGGGATTGTGGTTTT
TATCCTCTTGGTCTTTTTACAAGGTGGGATGCCAGATTTTAGTAGCAATCATGTCCGTGTTCAAGAAAATGGAGCAGCAG
CTAAGGCTGGTCTTCGAGATAATGACCAAATTGTCGCAATTAATGGTTACAAGGTGACTAGCTGGAATGATCTCACTGAG
GCTGTAGACCTTGCAACACGGGATCTAGGCCCGTCACAGACCATTAAGGTCACCTACAAGTCACATCAGCGCTTAAAAAC
GGTGGCTGTGAAACCACAAAAGCATGCAAAGACATACACGATAGGAGTTAAGGCGAGTCTGAAAACAGGATTTAAGGATA
AGCTCTTAGGCGGTCTAGAATTAGCTTGGAGTGGGGCGTTTACTATTTTGAATACTTTGAAAGGATTGATCACTGGCTTT
AGTCTCAATAAATTAGGTGGACCTGTTGCCATGTATGACATGTCCAATCAGGCTGCTCAAAACGGCTTAGAGTCAGTCTT
ATCTCTTATGGCAATGCTTTCGATCAATTTAGGGATCTTTAACCTGATTCCGATTCCTGCACTTGATGGGGGAAAAATCT
TGATGAATATCATTGAAGCCATTCGTCGCAAGCCTATCAAGCAAGAAACAGAGGCCTATATCACCCTAGCTGGGGTTGCT
ATCATGGTCGTATTGATGATTGCTGTGACATGGAATGATATCATGCGCGTCTTTTTCTAA

Domains

Predicted by InterproScan.

Peptidase family M50 (Peptidase_M50)

(6-405)

PDZ domain (PDZ_2)

(206-271)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  eeP Streptococcus thermophilus LMG 18311

68.81

100

0.69
  eeP Streptococcus thermophilus LMD-9

68.571

100

0.687