Detailed information NTG0477314

Bioinformatically predicted

Overview

• Name: ciaH
• Type: Regulator
• Locus tag: H7790_RS05050
• Genome accession: NZ_CP060645
• Coordinates: 1005458..1006768 (-)
• Length: 436 a.a.
• NCBI ID: WP_011184551.1
• Uniprot ID: -
• Organism: Streptococcus pyogenes strain TSPY1349
• Function: Required for optimal comC expression (predicted from homology) Competence regulation

Genomic Context

Location: 1000458..1011768

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H7790_RS05025 (H7790_05055)	-	1001109..1002161 (-)	1053	WP_002989701.1	BMP family protein	-
H7790_RS05030 (H7790_05060)	-	1002255..1002644 (-)	390	WP_011285547.1	cytidine deaminase	-
H7790_RS05035 (H7790_05065)	-	1003249..1003842 (-)	594	WP_010922352.1	class I SAM-dependent methyltransferase	-
H7790_RS05040 (H7790_05070)	coaA	1004110..1005030 (+)	921	WP_010922353.1	type I pantothenate kinase	-
H7790_RS05045 (H7790_05075)	rpsT	1005084..1005332 (+)	249	WP_009881183.1	30S ribosomal protein S20	-
H7790_RS05050 (H7790_05080)	ciaH	1005458..1006768 (-)	1311	WP_011184551.1	sensor histidine kinase	Regulator
H7790_RS05055 (H7790_05085)	ciaR	1006761..1007435 (-)	675	WP_002984519.1	response regulator transcription factor	Regulator
H7790_RS05060 (H7790_05090)	-	1007782..1010319 (-)	2538	WP_115230507.1	M1 family metallopeptidase	-
H7790_RS05065 (H7790_05095)	phoU	1010524..1011177 (-)	654	WP_002984514.1	phosphate signaling complex protein PhoU	-

Sequence

Protein

• Length: 436 a.a.
• Molecular weight: 50093.61 Da
• Isoelectric Point: 9.0837

>NTDB_id=477314 H7790_RS05050 WP_011184551.1 1005458..1006768(-) (ciaH) [Streptococcus pyogenes strain TSPY1349]
MNKLKKEILSDNYNHFFHFFAVFTGIFVIMTIIILQIMRFGVYSSVDSSLVSVSNNASSYANRTMARISSFYFDTENNII
KALPDSDSSKLLGTPAANTDIILFSANGTILNAFDAFSNYQNFHLDKHRLGSIETTSLMNFYGQEEKYHTITVRVHIKNY
PAVAYMMAVVNVEQLDRANERYERIIIIVMSVFWLISILASIYLAKWSRKPILESYEKQKMFVENASHELRTPLAVLQNR
LESLFRKPNETILENSEHLASSLDEVRNMRILTTNLLNLARRDDGINPQWTHLDTDFFNAIFENYELVAKEYGKIFYFQN
QVNRSLRMDKALLKQLITILFDNAIKYTDKNGIIEIIVKTTDKNLLISVIDNGPGITDEEKKKIFDRFYRVDKARTRQTG
GFGLGLALAQQIVMSLKGNITVKDNDPKGSIFEVKL

Nucleotide

• Length: 1311 bp

>NTDB_id=477314 H7790_RS05050 WP_011184551.1 1005458..1006768(-) (ciaH) [Streptococcus pyogenes strain TSPY1349]
ATGAATAAATTAAAAAAAGAGATTTTATCAGATAACTATAACCACTTTTTTCATTTTTTTGCGGTTTTTACAGGTATTTT
TGTCATTATGACTATTATTATCTTACAGATTATGCGGTTTGGCGTTTATTCGTCAGTTGACAGTAGTTTAGTTTCTGTTA
GTAATAATGCAAGTAGCTATGCTAATCGTACGATGGCTAGAATATCTTCTTTTTACTTTGATACTGAAAATAACATTATT
AAGGCGCTGCCTGATTCAGATAGTTCTAAGTTATTAGGAACGCCTGCAGCTAATACAGATATCATTTTGTTTAGTGCTAA
TGGAACAATTTTAAATGCTTTTGATGCGTTTTCTAACTATCAAAATTTTCATTTAGATAAACACCGTTTGGGGAGTATTG
AAACCACCAGTTTAATGAATTTTTATGGACAAGAAGAAAAATACCATACGATAACCGTAAGGGTTCATATCAAAAATTAT
CCTGCAGTTGCCTATATGATGGCAGTAGTAAATGTGGAACAATTAGACCGCGCTAATGAGCGTTATGAGCGCATTATTAT
TATAGTTATGAGTGTTTTTTGGCTAATTTCTATTTTAGCAAGTATTTATTTAGCCAAGTGGAGCAGAAAACCTATTTTAG
AAAGCTATGAAAAACAAAAAATGTTTGTTGAAAATGCTAGTCATGAATTAAGGACCCCTTTGGCGGTCTTACAGAATCGT
CTGGAATCGCTTTTTCGTAAGCCCAACGAAACGATATTAGAAAATAGTGAGCATCTCGCTTCTAGTTTAGACGAGGTTCG
CAACATGCGCATCTTAACAACTAATTTATTAAATTTAGCAAGACGAGATGATGGCATTAATCCACAGTGGACTCATTTAG
ATACAGATTTTTTTAATGCTATTTTTGAGAATTATGAACTAGTTGCTAAAGAATATGGAAAAATATTTTATTTTCAGAAC
CAAGTCAATAGATCGTTAAGAATGGATAAGGCTTTACTAAAACAATTAATAACGATTTTATTTGACAATGCTATTAAATA
TACAGATAAAAATGGTATTATTGAAATTATAGTGAAAACAACGGACAAAAATTTATTAATTTCTGTTATTGATAATGGTC
CAGGGATAACAGATGAAGAAAAGAAAAAGATTTTTGATCGTTTTTATCGAGTTGACAAAGCTAGAACACGGCAAACAGGT
GGATTTGGCTTGGGGTTGGCTTTAGCTCAGCAAATCGTGATGTCTTTAAAAGGAAATATTACAGTAAAGGATAATGATCC
TAAAGGTAGTATTTTTGAAGTCAAACTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (329-436)

• His Kinase A (phospho-acceptor) domain (HisKA) (220-285)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
ciaH	Streptococcus mutans UA159	57.895	100	0.58
ciaH	Streptococcus pneumoniae Rx1	51.37	100	0.516
ciaH	Streptococcus pneumoniae D39	51.37	100	0.516
ciaH	Streptococcus pneumoniae R6	51.37	100	0.516
ciaH	Streptococcus pneumoniae TIGR4	51.37	100	0.516