Detailed information    

insolico Bioinformatically predicted

Overview

Name   covS   Type   Regulator
Locus tag   LLH_RS04425 Genome accession   NC_017492
Coordinates   866876..868348 (+) Length   490 a.a.
NCBI ID   WP_041168194.1    Uniprot ID   -
Organism   Lactococcus cremoris subsp. cremoris A76     
Function   repress the expression of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 861876..873348
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  LLH_RS04395 (llh_4530) - 862342..863178 (+) 837 WP_041168193.1 metallophosphoesterase -
  LLH_RS04400 - 863271..864183 (+) 913 Protein_848 CHAP domain-containing protein -
  LLH_RS04405 - 864420..864782 (+) 363 WP_011834859.1 TIGR02328 family protein -
  LLH_RS04410 (llh_4545) - 865106..865351 (+) 246 WP_011676633.1 type B 50S ribosomal protein L31 -
  LLH_RS04415 (llh_4550) - 865484..866014 (+) 531 WP_014572328.1 DUF177 domain-containing protein -
  LLH_RS04420 (llh_4555) covR 866171..866863 (+) 693 WP_011676631.1 response regulator transcription factor Regulator
  LLH_RS04425 (llh_4560) covS 866876..868348 (+) 1473 WP_041168194.1 HAMP domain-containing histidine kinase Regulator
  LLH_RS04430 (llh_4565) - 868535..869776 (+) 1242 WP_014572330.1 ammonium transporter -
  LLH_RS04435 (llh_4570) - 869858..870199 (+) 342 WP_011676628.1 P-II family nitrogen regulator -
  LLH_RS04440 (llh_4575) murD 870368..871717 (+) 1350 WP_011834864.1 UDP-N-acetylmuramoyl-L-alanine--D-glutamate ligase -
  LLH_RS04445 (llh_4580) murG 871960..873033 (+) 1074 WP_011676626.1 undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase -

Sequence

Protein


Download         Length: 490 a.a.        Molecular weight: 55906.74 Da        Isoelectric Point: 4.7011

>NTDB_id=47693 LLH_RS04425 WP_041168194.1 866876..868348(+) (covS) [Lactococcus cremoris subsp. cremoris A76]
MKKLFTFNKKKETVEESSAKRSIMLRWAFANTVFCFITFTLFATLTYQLTISSFIKEEQRLLTGSMDSVEEVLEQADAPL
NSTNLNTYIEATSKIQNGESEGMSLGSIIGTRKAFYIYDLNHKLLYSTNRHDFGFQKQGNNEMKEIQGENPGYLVQRKIV
SKGTGQVVGYLQAFYDTTTYHRISNLLLVVLLILEIVALIVAQMIGYFMANYFMKPLEKLYQGMQEMASDPTNDFKPIEI
ESGDEIEELAHVYNDMMLKMKAYLEQQNRFVSDVSHELRTPLAVLDGHINLLNRWGKNDPEVLDESLQASLDEVDRMKKM
LEEMLALSRLENVDLSSEELDCDVGKVSNHALKNFQLLHEDFEIVLDNQLIYPVHARISENHFEQGLRILLDNAVKYSPD
DRKEIVITVSEDEQFVITSVSDKGIGIAEEDINHLFERFFRADKARNREIGGTGLGLPILARLAENYQGEIEVSSELGIG
STFTLKFPKM

Nucleotide


Download         Length: 1473 bp        

>NTDB_id=47693 LLH_RS04425 WP_041168194.1 866876..868348(+) (covS) [Lactococcus cremoris subsp. cremoris A76]
ATGAAAAAATTATTCACTTTCAACAAGAAAAAGGAAACGGTAGAAGAAAGTTCGGCTAAGCGGTCTATTATGCTTAGGTG
GGCTTTTGCTAACACCGTTTTTTGTTTTATTACTTTTACTCTTTTTGCAACATTAACTTATCAACTGACCATAAGTTCTT
TCATCAAGGAGGAACAAAGGTTATTGACAGGTTCAATGGACAGCGTTGAAGAGGTATTAGAACAAGCGGATGCTCCTTTA
AATTCAACTAATTTGAATACTTATATTGAAGCGACATCAAAGATTCAAAATGGGGAATCGGAAGGAATGAGTCTGGGAAG
TATCATCGGGACTCGGAAAGCATTTTATATTTATGATTTAAATCATAAATTACTATATTCAACTAATCGACATGATTTTG
GATTTCAAAAGCAAGGCAATAATGAGATGAAAGAAATTCAAGGTGAGAATCCAGGTTATTTAGTCCAAAGGAAGATTGTT
TCTAAAGGGACGGGACAGGTTGTAGGCTATTTACAGGCATTTTATGACACGACAACTTATCATCGGATTTCCAATCTCCT
TTTAGTCGTCTTGTTAATTTTAGAAATTGTCGCTTTAATCGTTGCGCAAATGATTGGTTATTTTATGGCGAATTATTTTA
TGAAGCCTTTAGAAAAACTTTATCAGGGAATGCAGGAAATGGCGAGCGACCCCACGAATGATTTCAAACCTATCGAAATT
GAAAGTGGTGATGAAATTGAAGAATTAGCTCATGTTTATAATGATATGATGCTGAAAATGAAAGCATACCTTGAACAGCA
AAATCGGTTTGTCTCTGATGTTTCACATGAATTAAGGACTCCGTTAGCAGTTTTGGACGGTCATATTAATCTCTTAAATC
GTTGGGGAAAAAATGATCCAGAAGTTTTGGATGAATCTTTGCAGGCGAGTTTGGATGAAGTAGACCGAATGAAGAAAATG
CTTGAAGAAATGCTTGCTTTATCTAGGCTTGAAAATGTAGATTTGTCCAGTGAAGAATTGGATTGTGACGTTGGGAAAGT
ATCTAATCATGCGCTTAAAAACTTCCAACTTCTACATGAGGATTTTGAGATTGTGCTTGATAATCAGCTTATCTACCCTG
TCCATGCCCGGATATCTGAAAATCATTTTGAACAAGGATTACGCATTTTGTTAGATAATGCTGTTAAGTATTCTCCGGAT
GATCGAAAGGAGATTGTGATTACTGTTTCAGAAGATGAACAGTTTGTCATTACTAGTGTTTCTGATAAAGGAATCGGAAT
TGCCGAAGAAGATATTAATCATCTTTTTGAGCGATTCTTTCGAGCGGATAAGGCACGTAACCGTGAGATTGGCGGAACTG
GTTTAGGTTTACCAATTCTTGCTCGTTTAGCCGAAAATTATCAAGGGGAGATTGAAGTTAGTTCTGAGCTTGGGATTGGT
TCAACTTTTACCTTAAAATTTCCAAAAATGTGA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(267-332)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(380-488)

HAMP domain (HAMP)

(208-258)

ArlS sensor domain (ArlS_N)

(54-185)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  covS Lactococcus lactis subsp. lactis strain DGCC12653

94.49

100

0.945

Multiple sequence alignment