Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   JZY07_RS02195 Genome accession   NZ_CP071305
Coordinates   418661..419302 (+) Length   213 a.a.
NCBI ID   WP_002937025.1    Uniprot ID   A0A0H3MTV8
Organism   Streptococcus suis strain SC183     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 413661..424302
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JZY07_RS02175 (JZY07_02175) - 413961..414698 (+) 738 WP_004194145.1 Stp1/IreP family PP2C-type Ser/Thr phosphatase -
  JZY07_RS02180 (JZY07_02180) stkP 414698..416692 (+) 1995 WP_024412392.1 Stk1 family PASTA domain-containing Ser/Thr kinase Regulator
  JZY07_RS02185 (JZY07_02185) liaF 417017..417676 (+) 660 WP_226317727.1 cell wall-active antibiotics response protein LiaF -
  JZY07_RS02190 (JZY07_02190) - 417673..418689 (+) 1017 WP_024384078.1 sensor histidine kinase -
  JZY07_RS02195 (JZY07_02195) vraR 418661..419302 (+) 642 WP_002937025.1 response regulator transcription factor Regulator
  JZY07_RS02200 (JZY07_02200) - 419352..420752 (+) 1401 WP_024412391.1 Cof-type HAD-IIB family hydrolase -
  JZY07_RS02205 (JZY07_02205) - 420754..421125 (+) 372 WP_002937017.1 S1 RNA-binding domain-containing protein -
  JZY07_RS02210 (JZY07_02210) cysK 421151..422077 (-) 927 WP_206974775.1 cysteine synthase A -
  JZY07_RS02215 (JZY07_02215) - 422167..422799 (-) 633 WP_024400101.1 YigZ family protein -
  JZY07_RS02220 (JZY07_02220) comFA/cflA 422856..424148 (+) 1293 WP_024400100.1 DEAD/DEAH box helicase Machinery gene

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23790.36 Da        Isoelectric Point: 4.8970

>NTDB_id=476667 JZY07_RS02195 WP_002937025.1 418661..419302(+) (vraR) [Streptococcus suis strain SC183]
MNTIRVMLVDDHEMVRLGLKSYLNLQPDVEVVAEASDGEEGLAKALEVKPDVVVMDLVMPKMTGVEATLALLKEWPQAQI
VILTSYLDNEKIYPVLEAGARGYMLKTSSADEILAAIRKVALGEYAIETEVEKKVEHHKRHPDLHDDLTAREREILTLLA
KGYDNQRIADESFISLKTVKTHVSNILSKLAVSDRTQAVVYAFQHGLVAQEDQ

Nucleotide


Download         Length: 642 bp        

>NTDB_id=476667 JZY07_RS02195 WP_002937025.1 418661..419302(+) (vraR) [Streptococcus suis strain SC183]
ATGAATACGATTCGAGTGATGCTAGTTGACGACCATGAGATGGTTCGTCTAGGATTGAAAAGTTACTTAAATTTACAGCC
AGATGTTGAAGTAGTTGCAGAAGCTAGTGATGGCGAGGAAGGTTTGGCTAAAGCATTAGAAGTTAAACCCGATGTTGTAG
TGATGGACTTGGTTATGCCCAAGATGACTGGCGTAGAAGCAACTCTGGCCTTGCTGAAGGAATGGCCGCAAGCGCAGATT
GTCATCCTGACCTCCTACCTAGATAATGAAAAAATCTATCCTGTGCTGGAAGCAGGAGCTCGTGGCTATATGTTGAAAAC
GTCAAGTGCTGACGAAATCTTAGCAGCCATCCGCAAGGTAGCTCTTGGAGAATATGCTATTGAGACAGAAGTAGAGAAAA
AAGTAGAGCACCATAAACGCCACCCAGATTTACATGATGACTTAACAGCCCGTGAACGCGAAATCTTGACGCTGTTAGCC
AAGGGATATGATAATCAACGAATTGCAGATGAGTCCTTCATTTCCCTAAAAACTGTTAAGACCCATGTTTCCAATATCTT
ATCCAAACTAGCTGTGAGCGATCGTACTCAAGCAGTTGTTTATGCTTTCCAGCATGGTTTGGTAGCGCAAGAGGACCAAT
AG

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(148-202)

Response regulator receiver domain (Response_reg)

(6-118)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0H3MTV8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

54.589

97.183

0.531
  degU Bacillus subtilis subsp. subtilis str. 168

38.938

100

0.413