Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   J0G24_RS10055 Genome accession   NZ_CP071259
Coordinates   2082292..2082948 (+) Length   218 a.a.
NCBI ID   WP_000611335.1    Uniprot ID   Q3Z2T8
Organism   Escherichia coli strain MEI005     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2077292..2087948
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  J0G24_RS10025 (J0G24_09915) dcyD 2078172..2079158 (+) 987 WP_001128219.1 D-cysteine desulfhydrase -
  J0G24_RS10030 (J0G24_09920) tcyL 2079173..2079841 (+) 669 WP_001158220.1 cystine ABC transporter permease -
  J0G24_RS10035 (J0G24_09925) tcyN 2079838..2080590 (+) 753 WP_001272994.1 L-cystine ABC transporter ATP-binding protein TcyN -
  J0G24_RS10040 (J0G24_09930) sdiA 2080820..2081542 (+) 723 WP_001154271.1 transcriptional regulator SdiA -
  J0G24_RS10045 (J0G24_09935) yecF 2081609..2081833 (-) 225 WP_000106474.1 DUF2594 family protein YecF -
  J0G24_RS10050 (J0G24_09940) yecU 2081820..2081996 (-) 177 WP_000590347.1 protein YecU -
  J0G24_RS25415 - 2082079..2082150 (-) 72 Protein_1972 transcriptional regulator -
  J0G24_RS10055 (J0G24_09945) letA 2082292..2082948 (+) 657 WP_000611335.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  J0G24_RS10060 (J0G24_09950) uvrC 2082945..2084777 (+) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  J0G24_RS10065 (J0G24_09955) pgsA 2084834..2085382 (+) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  J0G24_RS10085 (J0G24_09975) yecA 2086032..2086697 (+) 666 WP_000847902.1 UPF0149 family protein YecA -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23892.65 Da        Isoelectric Point: 6.9614

>NTDB_id=476359 J0G24_RS10055 WP_000611335.1 2082292..2082948(+) (letA) [Escherichia coli strain MEI005]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRTNAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=476359 J0G24_RS10055 WP_000611335.1 2082292..2082948(+) (letA) [Escherichia coli strain MEI005]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGACAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACCGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTCGTGAGTGCGATTCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(4-115)

Bacterial regulatory proteins, luxR family (GerE)

(149-204)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q3Z2T8

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

51.208

94.954

0.486
  letA Legionella pneumophila strain ERS1305867

51.208

94.954

0.486