Detailed information    

insolico Bioinformatically predicted

Overview

Name   sigH   Type   Regulator
Locus tag   H8N04_RS11950 Genome accession   NZ_CP060491
Coordinates   2363973..2364542 (-) Length   189 a.a.
NCBI ID   WP_000872873.1    Uniprot ID   -
Organism   Staphylococcus aureus strain WH39     
Function   promote expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2358973..2369542
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  H8N04_RS11910 (H8N04_11915) - 2359447..2360055 (-) 609 WP_000020304.1 class I SAM-dependent methyltransferase -
  H8N04_RS11915 (H8N04_11920) rplL 2360230..2360598 (-) 369 WP_001273586.1 50S ribosomal protein L7/L12 -
  H8N04_RS11920 (H8N04_11925) rplJ 2360641..2361141 (-) 501 WP_001273085.1 50S ribosomal protein L10 -
  H8N04_RS11925 (H8N04_11930) rplA 2361413..2362105 (-) 693 WP_001074619.1 50S ribosomal protein L1 -
  H8N04_RS11930 (H8N04_11935) rplK 2362313..2362735 (-) 423 WP_001085792.1 50S ribosomal protein L11 -
  H8N04_RS11935 (H8N04_11940) nusG 2362916..2363464 (-) 549 WP_001288302.1 transcription termination/antitermination protein NusG -
  H8N04_RS11940 (H8N04_11945) secE 2363477..2363659 (-) 183 WP_001074474.1 preprotein translocase subunit SecE -
  H8N04_RS11945 (H8N04_11950) rpmG 2363715..2363858 (-) 144 WP_001788193.1 50S ribosomal protein L33 -
  H8N04_RS11950 (H8N04_11955) sigH 2363973..2364542 (-) 570 WP_000872873.1 sigma-70 family RNA polymerase sigma factor Regulator
  H8N04_RS11955 (H8N04_11960) - 2364623..2365147 (-) 525 WP_000664738.1 NYN domain-containing protein -
  H8N04_RS11960 (H8N04_11965) rlmB 2365147..2365893 (-) 747 WP_048665442.1 23S rRNA (guanosine(2251)-2'-O)-methyltransferase RlmB -
  H8N04_RS11965 (H8N04_11970) - 2365901..2366305 (-) 405 WP_000370182.1 Mini-ribonuclease 3 -
  H8N04_RS11970 (H8N04_11975) cysS 2366298..2367698 (-) 1401 WP_000631963.1 cysteine--tRNA ligase -
  H8N04_RS11975 (H8N04_11980) cysE 2367682..2368329 (-) 648 WP_078104161.1 serine O-acetyltransferase -

Sequence

Protein


Download         Length: 189 a.a.        Molecular weight: 23028.91 Da        Isoelectric Point: 9.4170

>NTDB_id=476329 H8N04_RS11950 WP_000872873.1 2363973..2364542(-) (sigH) [Staphylococcus aureus strain WH39]
MKYDLTTQDSTIKRNNAINDKDFEKLVMDLQPLIIRRIKTFGFNHYDLEDLYQEILIRMYRSVQTFDFSGEQPFTNYVQC
LITSVKYDYLRKYLATNKRMDNLINEYRVTYPCAIKRFDVENNYLNKLAIKELICQFKYLSAFEKDVMYLMCEQYKPREI
AQLMHVKEKVIYNAIQRCKNKIKRYFKMI

Nucleotide


Download         Length: 570 bp        

>NTDB_id=476329 H8N04_RS11950 WP_000872873.1 2363973..2364542(-) (sigH) [Staphylococcus aureus strain WH39]
TTGAAATACGATTTGACAACTCAAGACAGTACAATCAAACGTAACAATGCAATAAATGATAAAGACTTCGAAAAGTTAGT
AATGGATCTACAACCATTAATTATTCGACGCATCAAAACATTTGGATTTAATCATTATGATTTAGAAGACTTATATCAAG
AAATACTTATACGGATGTATAGGTCGGTCCAAACATTTGATTTTAGTGGAGAGCAGCCTTTCACAAATTATGTTCAATGT
TTAATTACGTCTGTAAAGTATGATTATTTGAGAAAATATTTAGCTACAAATAAAAGAATGGATAATTTGATTAATGAATA
TAGAGTTACGTATCCATGTGCAATAAAGCGTTTTGATGTTGAAAACAATTATTTGAATAAATTAGCAATTAAAGAGTTGA
TTTGTCAGTTTAAGTATTTGAGTGCATTTGAAAAAGATGTCATGTATTTAATGTGTGAACAATATAAGCCGAGAGAAATT
GCTCAATTGATGCATGTAAAAGAGAAAGTGATTTATAATGCCATACAACGATGTAAAAATAAAATAAAACGTTATTTCAA
AATGATTTGA

Domains

Predicted by InterproScan.

Sigma-70 region 2 (Sigma70_r2)

(26-92)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  sigH Staphylococcus aureus N315

99.471

100

0.995
  sigH Staphylococcus aureus MW2

98.413

100

0.984