Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   JY392_RS14090 Genome accession   NZ_CP071073
Coordinates   2863380..2864036 (-) Length   218 a.a.
NCBI ID   WP_000611328.1    Uniprot ID   P66797
Organism   Escherichia coli strain 3347558     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 2858380..2869036
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JY392_RS14060 (JY392_14055) yecA 2859631..2860296 (-) 666 WP_000847882.1 UPF0149 family protein YecA -
  JY392_RS14080 (JY392_14075) pgsA 2860946..2861494 (-) 549 WP_001160187.1 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase -
  JY392_RS14085 (JY392_14080) uvrC 2861551..2863383 (-) 1833 WP_001283421.1 excinuclease ABC subunit UvrC Machinery gene
  JY392_RS14090 (JY392_14085) letA 2863380..2864036 (-) 657 WP_000611328.1 UvrY/SirA/GacA family response regulator transcription factor Regulator
  JY392_RS14095 (JY392_14090) yecU 2864332..2864508 (+) 177 WP_000590347.1 protein YecU -
  JY392_RS14100 (JY392_14095) yecF 2864495..2864719 (+) 225 WP_000106474.1 DUF2594 family protein YecF -
  JY392_RS14105 (JY392_14100) sdiA 2864787..2865509 (-) 723 WP_001154273.1 transcriptional regulator SdiA -
  JY392_RS14110 (JY392_14105) tcyN 2865739..2866491 (-) 753 WP_001272982.1 L-cystine ABC transporter ATP-binding protein TcyN -
  JY392_RS14115 (JY392_14110) tcyL 2866488..2867156 (-) 669 WP_001158220.1 cystine ABC transporter permease -
  JY392_RS14120 (JY392_14115) dcyD 2867171..2868157 (-) 987 WP_001128228.1 D-cysteine desulfhydrase -

Sequence

Protein


Download         Length: 218 a.a.        Molecular weight: 23862.63 Da        Isoelectric Point: 6.9614

>NTDB_id=476013 JY392_RS14090 WP_000611328.1 2863380..2864036(-) (letA) [Escherichia coli strain 3347558]
MINVLLVDDHELVRAGIRRILEDIKGIKVVGEASCGEDAVKWCRANAVDVVLMDMSMPGIGGLEATRKIARSTADVKIIM
LTVHTENPLPAKVMQAGAAGYLSKGAAPQEVVSAIRSVYSGQRYIASDIAQQMALSQIEPEKTESPFASLSERELQIMLM
ITKGQKVNEISEQLNLSPKTVNSYRYRMFSKLNIHGDVELTHLAIRHGLCNAETLSSQ

Nucleotide


Download         Length: 657 bp        

>NTDB_id=476013 JY392_RS14090 WP_000611328.1 2863380..2864036(-) (letA) [Escherichia coli strain 3347558]
TTGATCAACGTTCTACTTGTTGATGACCACGAACTGGTGCGCGCAGGGATACGACGCATTCTGGAAGATATAAAGGGTAT
AAAAGTCGTCGGTGAGGCATCGTGCGGTGAAGACGCCGTTAAGTGGTGCCGGGCAAATGCCGTTGACGTGGTGCTAATGG
ACATGAGTATGCCGGGCATTGGCGGTCTTGAGGCGACGCGTAAAATCGCGCGTTCCACAGCTGATGTCAAAATCATCATG
CTTACGGTCCATACAGAAAACCCTTTACCAGCGAAAGTCATGCAGGCCGGTGCTGCGGGCTACCTCAGCAAAGGCGCGGC
TCCGCAGGAAGTAGTGAGTGCGATCCGTTCTGTCTATTCAGGGCAGCGTTACATTGCTTCTGACATCGCTCAACAAATGG
CGTTAAGCCAGATCGAACCAGAAAAAACAGAAAGCCCATTTGCCAGTTTGTCTGAACGTGAATTGCAGATTATGCTGATG
ATCACCAAGGGCCAGAAGGTCAATGAGATCTCAGAACAGCTCAATCTCAGTCCGAAAACGGTGAACAGCTACCGCTATCG
TATGTTCAGTAAACTAAACATTCATGGCGATGTTGAGCTGACTCACCTGGCAATTCGCCATGGTCTGTGTAATGCGGAGA
CATTATCAAGTCAGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(149-204)

Response regulator receiver domain (Response_reg)

(4-115)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P66797

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

50.725

94.954

0.482
  letA Legionella pneumophila strain ERS1305867

50.725

94.954

0.482