Detailed information NTG0475998

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: H8P15_RS16635
• Genome accession: NZ_CP060420
• Coordinates: 3395148..3396311 (-)
• Length: 387 a.a.
• NCBI ID: WP_007407484.1
• Uniprot ID: A3KLC1
• Organism: Bacillus velezensis strain J17-4
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3390148..3401311

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
H8P15_RS16605 (H8P15_16605)	-	3390412..3390831 (-)	420	WP_012118571.1	TIGR03826 family flagellar region protein	-
H8P15_RS16610 (H8P15_16610)	comFC	3390905..3391594 (-)	690	WP_196770545.1	phosphoribosyltransferase family protein	Machinery gene
H8P15_RS16615 (H8P15_16615)	-	3391600..3391884 (-)	285	WP_003151389.1	competence protein ComFB	-
H8P15_RS16620 (H8P15_16620)	comFA	3391942..3393327 (-)	1386	WP_032876163.1	DEAD/DEAH box helicase	Machinery gene
H8P15_RS16625 (H8P15_16625)	-	3393436..3394284 (-)	849	WP_032876160.1	DegV family protein	-
H8P15_RS16630 (H8P15_16630)	degU	3394382..3395071 (-)	690	WP_003219701.1	two-component system response regulator DegU	Regulator
H8P15_RS16635 (H8P15_16635)	degS	3395148..3396311 (-)	1164	WP_007407484.1	two-component sensor histidine kinase DegS	Regulator
H8P15_RS16640 (H8P15_16640)	-	3396534..3397181 (+)	648	WP_007614107.1	YigZ family protein	-
H8P15_RS16645 (H8P15_16645)	-	3397186..3398367 (+)	1182	WP_032876157.1	LCP family protein	-
H8P15_RS16650 (H8P15_16650)	-	3398466..3399542 (-)	1077	WP_003151382.1	MraY family glycosyltransferase	-
H8P15_RS16655 (H8P15_16655)	-	3399675..3400871 (-)	1197	WP_032876154.1	glycosyltransferase	-

Sequence

Protein

• Length: 387 a.a.
• Molecular weight: 45014.78 Da
• Isoelectric Point: 6.8616

>NTDB_id=475998 H8P15_RS16635 WP_007407484.1 3395148..3396311(-) (degS) [Bacillus velezensis strain J17-4]
MNKSKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVHTRHARNRLSEVSR
NFHKFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLRQVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGTEDGFQEIRNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGDTENQRLAPQFEVALFRLAQEAVTNALKHSESEEITVKVEV
TADFVVLIIKDNGKGFDIKDAKQKKNKSFGLLGMKERVDLLEGTITIDSKIGLGTFIMIKVPLSLGL

Nucleotide

• Length: 1164 bp

>NTDB_id=475998 H8P15_RS16635 WP_007407484.1 3395148..3396311(-) (degS) [Bacillus velezensis strain J17-4]
ATGAATAAATCGAAGATGGACTCCAAAGTTTTGGATTCTATACTTATGAAAATGCTGAAAACCGTGGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGAGAGCAGTCGCGCCAGCAATATGAGCAGCTGGTTGAAGAACTCAAACAGATCAAACAGCAGG
TGTACGAAGTCATTGAGCTGGGCGACAAACTTGAAGTTCATACGCGGCACGCACGAAACCGCTTGTCTGAAGTAAGCAGA
AATTTCCATAAGTTCAGCGAAGAAGAAATTCGCAACGCCTATGAAAAGGCGCACAAACTTCAAGTGGAACTGACGATGAT
CCAGCAGCGTGAAAAGCAGCTGCGGGAGCGCAGAGATGATTTAGAACGCCGGCTTTTGGGGCTTCAGGAAATTATTGAAC
GGTCAGAATCATTGGTCAGCCAAATAACCGTCGTTCTGAATTACCTGAATCAAGACCTTCGCCAAGTAGGGCTTCTTCTT
GCCGATGCGCAGGCTAAACAAGATTTCGGTTTAAGAATCATTGAAGCCCAAGAGGAAGAAAGAAAAAGAGTTTCCAGAGA
AATTCATGACGGTCCCGCGCAAATGCTGGCAAATGTCATGATGAGATCGGAATTAATTGAACGGATCTTCCGCGACCGCG
GCACGGAGGACGGATTTCAGGAAATCAGAAATCTACGGCAGAATGTGCGGAATGCCCTTTACGAAGTCAGAAGGATTATA
TATGATTTAAGACCGATGGCATTGGACGATCTCGGGCTGATTCCGACACTGAGAAAATATCTTTATACAACTGAAGAATA
CAACGGAAAGGTGAAAATACATTTTCAGTGCATCGGAGACACAGAGAACCAAAGGCTTGCCCCGCAATTTGAAGTGGCGC
TTTTCCGTCTCGCTCAGGAAGCCGTCACAAATGCACTCAAGCATTCAGAATCAGAGGAAATTACAGTAAAAGTGGAAGTA
ACCGCTGATTTTGTCGTTCTCATCATTAAGGACAATGGAAAAGGCTTTGATATTAAGGATGCTAAACAAAAGAAAAACAA
GTCATTCGGCTTGCTGGGAATGAAAGAAAGAGTAGATCTGCTTGAAGGAACGATAACGATAGACTCTAAAATAGGTCTTG
GGACATTTATCATGATTAAGGTTCCGTTATCTCTCGGCCTATAA

Domains

Predicted by InterproScan.

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

• Histidine kinase (HisKA_3) (180-248)

3D structure

• AlphaFold DB: A3KLC1

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	95.584	99.483	0.951