Detailed information NTG0475930

Bioinformatically predicted

Overview

• Name: disA
• Type: Machinery gene
• Locus tag: JHY03_RS14755
• Genome accession: NZ_CP071044
• Coordinates: 3376206..3377330 (+)
• Length: 374 a.a.
• NCBI ID: WP_031124035.1
• Uniprot ID: A0A6N9VPB8
• Organism: Streptomyces sp. CA-256286
• Function: homologous recombination (predicted from homology) Homologous recombination

Genomic Context

Location: 3371206..3382330

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JHY03_RS14740 (JHY03_29660)	-	3371736..3372578 (+)	843	WP_207564324.1	hypothetical protein	-
JHY03_RS14745 (JHY03_29670)	-	3372668..3374545 (-)	1878	WP_207564325.1	hypothetical protein	-
JHY03_RS14750 (JHY03_29680)	radA/sms	3374703..3376124 (+)	1422	WP_055561464.1	DNA repair protein RadA	Machinery gene
JHY03_RS14755 (JHY03_29690)	disA	3376206..3377330 (+)	1125	WP_031124035.1	DNA integrity scanning diadenylate cyclase DisA	Machinery gene
JHY03_RS14760 (JHY03_29700)	-	3377509..3378342 (-)	834	WP_233842058.1	hypothetical protein	-
JHY03_RS14765 (JHY03_29710)	-	3378585..3379496 (+)	912	WP_031124033.1	A/G-specific adenine glycosylase	-
JHY03_RS14770 (JHY03_29720)	-	3379652..3380377 (+)	726	WP_202705375.1	SigE family RNA polymerase sigma factor	-
JHY03_RS14775 (JHY03_29730)	-	3380479..3381138 (+)	660	WP_032775725.1	hypothetical protein	-
JHY03_RS14780 (JHY03_29740)	cseB	3381157..3381870 (+)	714	WP_207564326.1	two-component system response regulator CseB	-

Sequence

Protein

• Length: 374 a.a.
• Molecular weight: 40376.32 Da
• Isoelectric Point: 5.0230

>NTDB_id=475930 JHY03_RS14755 WP_031124035.1 3376206..3377330(+) (disA) [Streptomyces sp. CA-256286]
MAANDRAAAPGKSGQGTGNEALMRASLSAVAPGMALRDGLERILRGNTGGLIVLGMDRTVESMCTGGFVLDVEFTATRLR
ELCKLDGALILDKDMTKILRAGVQLVPDASIHTEETGTRHRTADRVSKACGFPVVSVSQSMRLIALYVDGERRVLEESSA
ILSRANQALATLERYKLRLDEVAGTLSALEIEDLVTVRDVTAVAQRLEMVRRIATEIAEYVVELGTDGRLLSLQLDELIA
GVEPERELVVRDYVPEPTAKRSRTVAEALTELDALSHTELLELPVVARALGYSGSPETLDSAVSPRGFRLLAKVPRLPGA
IIERLVEHFGGLQKLLAASVDDLQTVDGVGEARARSVREGLSRLAESSILERYV

Nucleotide

• Length: 1125 bp

>NTDB_id=475930 JHY03_RS14755 WP_031124035.1 3376206..3377330(+) (disA) [Streptomyces sp. CA-256286]
GTGGCAGCCAACGACCGGGCGGCAGCGCCCGGAAAGTCCGGCCAAGGCACCGGCAACGAAGCGCTGATGCGCGCCTCGTT
GAGCGCGGTCGCACCCGGAATGGCCCTGCGGGACGGCCTGGAGCGCATTCTCCGGGGCAATACCGGCGGGCTGATCGTCC
TGGGCATGGACAGGACCGTCGAATCGATGTGTACCGGCGGGTTCGTGCTGGACGTGGAGTTCACCGCGACCCGACTGCGC
GAGCTGTGCAAGCTCGACGGGGCACTGATCCTCGACAAGGACATGACCAAGATCCTGCGGGCCGGTGTGCAGCTGGTCCC
GGACGCCTCGATCCACACGGAGGAGACGGGGACCCGTCACCGTACGGCGGACCGGGTCTCCAAGGCGTGCGGTTTCCCCG
TCGTCTCGGTCTCCCAGTCGATGCGGCTGATCGCGCTGTACGTGGACGGGGAGCGGCGGGTCCTGGAGGAGTCCTCCGCG
ATCCTCTCCCGGGCCAATCAGGCGCTCGCCACCCTGGAGCGGTACAAGCTGCGCCTGGACGAGGTGGCCGGGACGCTCTC
CGCGCTGGAGATCGAGGACCTGGTCACCGTCCGGGACGTGACGGCGGTGGCGCAGCGGCTGGAGATGGTGCGGCGGATCG
CGACCGAGATCGCGGAGTACGTGGTCGAGCTCGGCACCGACGGACGGCTCCTCTCGCTCCAGCTGGACGAGCTGATCGCG
GGCGTGGAGCCGGAGCGGGAGCTGGTCGTCCGGGACTACGTGCCCGAGCCGACGGCGAAACGGTCACGCACGGTGGCGGA
GGCGCTGACCGAGCTGGACGCGCTGAGCCACACGGAGCTGCTGGAGCTGCCGGTGGTGGCGCGGGCGCTGGGGTACAGCG
GCTCGCCCGAGACGCTGGACTCGGCGGTCTCCCCGCGGGGTTTCCGGCTGCTGGCGAAGGTGCCGAGGCTGCCGGGCGCG
ATCATCGAGCGGCTGGTGGAGCACTTCGGGGGCCTGCAGAAGCTGCTGGCGGCGAGTGTGGACGACCTCCAGACCGTGGA
CGGGGTCGGGGAGGCGCGGGCGCGGAGCGTGCGGGAGGGGCTCTCGCGGCTGGCGGAGTCGTCGATCCTGGAGCGGTACG
TCTGA

Domains

Predicted by InterProScan.

• DisA bacterial checkpoint controller nucleotide-binding (DAC) (38-151)

• Helix-hairpin-helix motif (HHH_2) (324-359)

• DisA bacterial checkpoint controller linker region (DisA-linker) (155-297)

3D structure

• AlphaFold DB: A0A6N9VPB8

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
disA	Bacillus subtilis subsp. subtilis str. 168	45.152	96.524	0.436