Detailed information    

insolico Bioinformatically predicted

Overview

Name   vraR   Type   Regulator
Locus tag   JHY03_RS09395 Genome accession   NZ_CP071044
Coordinates   2132579..2133268 (+) Length   229 a.a.
NCBI ID   WP_015608290.1    Uniprot ID   A0A6N9VHQ1
Organism   Streptomyces sp. CA-256286     
Function   repress expression of competence genes (predicted from homology)   
Competence regulation

Genomic Context

Location: 2127579..2138268
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  JHY03_RS09375 (JHY03_18820) - 2128064..2128735 (+) 672 WP_031122322.1 TetR family transcriptional regulator -
  JHY03_RS09380 (JHY03_18830) - 2128832..2130040 (+) 1209 WP_031122323.1 alpha/beta hydrolase -
  JHY03_RS09385 (JHY03_18840) - 2130127..2131095 (+) 969 WP_055560326.1 DUF4429 domain-containing protein -
  JHY03_RS09390 (JHY03_18850) - 2131209..2132582 (+) 1374 WP_094212654.1 sensor histidine kinase -
  JHY03_RS09395 (JHY03_18860) vraR 2132579..2133268 (+) 690 WP_015608290.1 response regulator transcription factor Regulator
  JHY03_RS09400 (JHY03_18870) - 2133398..2134495 (+) 1098 WP_207564061.1 alpha/beta hydrolase -
  JHY03_RS09405 (JHY03_18880) - 2134492..2135757 (+) 1266 WP_207564062.1 acyltransferase -
  JHY03_RS09410 (JHY03_18890) - 2135845..2136864 (-) 1020 WP_202705029.1 aldo/keto reductase -
  JHY03_RS09415 (JHY03_18900) - 2136864..2137379 (-) 516 WP_031122329.1 MerR family transcriptional regulator -
  JHY03_RS09420 (JHY03_18910) - 2137462..2138001 (-) 540 WP_031122330.1 hypothetical protein -

Sequence

Protein


Download         Length: 229 a.a.        Molecular weight: 24348.02 Da        Isoelectric Point: 4.9303

>NTDB_id=475918 JHY03_RS09395 WP_015608290.1 2132579..2133268(+) (vraR) [Streptomyces sp. CA-256286]
MTIRVIIVDDQAMVRAGFAALLAAQSDIDVVGEAADGRQGVDVSRNQHPDVVLMDVRMPEMDGLAAARELLNPPIGVVHR
PKVLMLTTFDVDDYVYEALRAGASGFLLKDAPPADLIAAVRVVAAGDALLAPSVTRRLIADFAAQRPSGATRGGQALRLN
ALTPRESEVLELIARGLSNQEIAERLVLAEQTVKTHIGRVLAKLDLRDRAQAVIFAYESGLVTPGDAGA

Nucleotide


Download         Length: 690 bp        

>NTDB_id=475918 JHY03_RS09395 WP_015608290.1 2132579..2133268(+) (vraR) [Streptomyces sp. CA-256286]
GTGACCATCCGCGTGATCATCGTCGACGACCAGGCCATGGTGCGGGCGGGGTTCGCGGCGCTGCTGGCCGCGCAGAGCGA
CATCGACGTGGTGGGCGAGGCGGCGGACGGCCGGCAGGGCGTGGACGTCAGCCGCAACCAGCACCCGGATGTGGTCCTGA
TGGACGTGCGGATGCCGGAGATGGACGGACTGGCCGCCGCCCGCGAGCTGTTGAACCCGCCGATCGGGGTGGTGCACCGG
CCGAAGGTGCTGATGCTGACCACCTTCGACGTGGACGACTACGTGTACGAGGCGCTCCGCGCCGGGGCCTCCGGGTTCCT
GCTGAAGGACGCTCCCCCGGCCGATCTGATCGCGGCGGTACGGGTGGTGGCGGCGGGCGACGCGCTGCTGGCGCCCTCCG
TGACGCGGCGGCTGATCGCGGACTTCGCGGCGCAGCGGCCCTCGGGGGCGACGCGTGGCGGGCAGGCTCTGCGGCTGAAC
GCCCTGACCCCGCGCGAGAGCGAGGTGCTGGAGCTGATCGCCCGGGGGCTGTCGAACCAGGAGATCGCGGAGCGGCTGGT
GCTGGCCGAGCAGACGGTGAAGACGCACATCGGCCGGGTGCTGGCCAAGCTGGACCTGCGGGACCGGGCGCAGGCGGTGA
TCTTCGCGTACGAGTCGGGGCTGGTGACGCCGGGGGACGCGGGGGCCTGA

Domains

Predicted by InterProScan.

Response regulator receiver domain (Response_reg)

(5-121)

Bacterial regulatory proteins, luxR family (GerE)

(161-216)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A6N9VHQ1

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  vraR Staphylococcus aureus N315

41.071

97.817

0.402
  degU Bacillus subtilis subsp. subtilis str. 168

37.445

99.127

0.371