Detailed information NTG0475887

Bioinformatically predicted

Overview

• Name: degS
• Type: Regulator
• Locus tag: JS609_RS18215
• Genome accession: NZ_CP071043
• Coordinates: 3525256..3526413 (-)
• Length: 385 a.a.
• NCBI ID: WP_003227983.1
• Uniprot ID: Q3LHN6
• Organism: Bacillus subtilis isolate ELA2001105
• Function: phosphorylation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3520256..3531413

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
JS609_RS18185 (JS609_03583)	yvyF	3520510..3520929 (-)	420	WP_003227995.1	TIGR03826 family flagellar region protein	-
JS609_RS18190 (JS609_03584)	comFC	3521002..3521724 (-)	723	WP_128993465.1	comF operon protein ComFC	Machinery gene
JS609_RS18195 (JS609_03585)	comFB	3521688..3521984 (-)	297	WP_015483764.1	late competence protein ComFB	-
JS609_RS18200 (JS609_03586)	comFA	3522044..3523435 (-)	1392	WP_003243962.1	ATP-dependent helicase ComFA	Machinery gene
JS609_RS18205 (JS609_03587)	fakBA	3523541..3524386 (-)	846	WP_003244125.1	DegV family protein	-
JS609_RS18210 (JS609_03588)	degU	3524484..3525173 (-)	690	WP_003219701.1	two-component system response regulator DegU	-
JS609_RS18215 (JS609_03589)	degS	3525256..3526413 (-)	1158	WP_003227983.1	two-component sensor histidine kinase DegS	Regulator
JS609_RS18220 (JS609_03590)	yvyE	3526630..3527283 (+)	654	WP_003227979.1	YigZ family protein	-
JS609_RS18225 (JS609_03591)	tagV	3527283..3528458 (+)	1176	WP_213414818.1	LCP family protein	-
JS609_RS18230 (JS609_03592)	tagO	3528531..3529607 (-)	1077	WP_003227975.1	MraY family glycosyltransferase	-
JS609_RS18235 (JS609_03593)	tuaH	3529752..3530945 (-)	1194	WP_225722189.1	teichuronic acid biosynthesis protein TuaH	-

Sequence

Protein

• Length: 385 a.a.
• Molecular weight: 44957.76 Da
• Isoelectric Point: 6.2957

>NTDB_id=475887 JS609_RS18215 WP_003227983.1 3525256..3526413(-) (degS) [Bacillus subtilis isolate ELA2001105]
MNKTKMDSKVLDSILMKMLKTVDGSKDEVFQIGEQSRQQYEQLVEELKQIKQQVYEVIELGDKLEVQTRHARNRLSEVSR
NFHRFSEEEIRNAYEKAHKLQVELTMIQQREKQLRERRDDLERRLLGLQEIIERSESLVSQITVVLNYLNQDLREVGLLL
ADAQAKQDFGLRIIEAQEEERKRVSREIHDGPAQMLANVMMRSELIERIFRDRGAEDGFQEIKNLRQNVRNALYEVRRII
YDLRPMALDDLGLIPTLRKYLYTTEEYNGKVKIHFQCIGETEDQRLAPQFEVALFRLAQEAVSNALKHSESEEITVKVEI
TKDFVILMIKDNGKGFDLKEAKEKKNKSFGLLGMKERVDLLEGTMTIDSKIGLGTFIMIKVPLSL

Nucleotide

• Length: 1158 bp

>NTDB_id=475887 JS609_RS18215 WP_003227983.1 3525256..3526413(-) (degS) [Bacillus subtilis isolate ELA2001105]
ATGAATAAAACAAAGATGGATTCCAAAGTGCTGGATTCTATTTTGATGAAGATGCTGAAAACCGTTGACGGGAGCAAGGA
CGAGGTTTTTCAAATCGGGGAGCAGTCACGCCAGCAGTATGAACAGCTGGTCGAAGAACTGAAACAAATTAAACAGCAGG
TGTATGAAGTGATTGAGCTTGGCGATAAACTTGAAGTGCAAACCCGCCATGCGAGAAACCGTTTATCCGAGGTCAGCCGT
AATTTTCATAGATTCAGTGAAGAGGAAATCCGCAATGCTTATGAAAAAGCCCATAAGCTGCAGGTAGAATTGACGATGAT
CCAGCAGCGTGAGAAGCAATTGCGCGAACGGCGGGACGATTTGGAGCGCAGATTGCTAGGGCTTCAGGAAATCATTGAGC
GGTCAGAATCATTAGTAAGCCAAATTACAGTTGTGCTCAACTACTTGAATCAGGATTTGCGCGAAGTTGGACTGCTTCTT
GCTGATGCTCAGGCAAAACAGGATTTCGGCTTAAGAATTATTGAGGCGCAGGAAGAAGAGCGAAAAAGAGTCTCAAGAGA
AATCCATGACGGACCCGCTCAAATGCTGGCGAATGTTATGATGAGATCGGAATTAATCGAGCGGATTTTCCGTGACCGGG
GCGCAGAGGACGGATTCCAAGAAATTAAAAATCTCCGCCAAAATGTTCGGAATGCCCTTTACGAAGTGAGAAGGATTATA
TATGATTTAAGACCGATGGCCCTTGATGACCTAGGCCTGATTCCAACTTTAAGAAAATATCTATATACAACCGAGGAATA
TAACGGGAAGGTCAAAATACATTTTCAGTGCATTGGAGAAACAGAGGATCAGAGGCTAGCGCCTCAGTTTGAGGTTGCGC
TCTTCAGGCTCGCACAGGAAGCTGTGTCTAATGCGCTAAAGCATTCTGAATCTGAAGAAATTACAGTCAAAGTTGAGATC
ACAAAGGATTTTGTGATTTTAATGATAAAAGATAACGGTAAAGGGTTCGACCTGAAGGAAGCGAAAGAGAAGAAAAACAA
ATCATTCGGCTTGCTGGGCATGAAAGAAAGAGTAGATTTATTGGAAGGAACGATGACAATAGATTCGAAAATAGGTCTTG
GGACATTTATTATGATTAAGGTTCCGTTATCTCTTTGA

Domains

Predicted by InterProScan.

• Histidine kinase (HisKA_3) (180-248)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (291-384)

• Sensor protein DegS (DegS) (12-170)

3D structure

• AlphaFold DB: Q3LHN6

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
degS	Bacillus subtilis subsp. subtilis str. 168	100	100	1